(+)-Cloprostenol
- Product Name
- (+)-Cloprostenol
- CAS No.
- 54276-21-0
- Chemical Name
- (+)-Cloprostenol
- Synonyms
- Superphan;cGMP Superphan;(+)-Cloprostenol;Cloprostenol Impurity 2;Cloprostenol in Acetonitrile;(+)-16-M-CHLOROPHENOXY TETRANOR PROSTAGLANDIN F2ALPHA;(+)-9ALPHA,11ALPHA,15-TRIHYDROXY-16-(3-CHLOROPHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;(Z)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-Chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoic acid;(5Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, (5Z)-
- CBNumber
- CB8467074
- Molecular Formula
- C22H29ClO6
- Formula Weight
- 424.92
- MOL File
- 54276-21-0.mol
(+)-Cloprostenol Property
- Boiling point:
- 628.0±55.0 °C(Predicted)
- Density
- 1.321
- storage temp.
- Store at -20°C
- solubility
- DMF: >100 mg/ml (from Fluprostenol); DMSO: >100 mg/ml (from Fluprostenol; Ethanol: >100 mg/ml (from Fluprostenol); PBS pH 7.2: >16 mg/ml (from Fluprostenol)
- pka
- 4.76±0.10(Predicted)
- form
- Oil
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 16765
- Product name
- (+)-Cloprostenol
- Purity
- ≥97%
- Packaging
- 1mg
- Price
- $72
- Updated
- 2024/03/01
- Product number
- 16765
- Product name
- (+)-Cloprostenol
- Purity
- ≥97%
- Packaging
- 5mg
- Price
- $319
- Updated
- 2024/03/01
- Product number
- 16765
- Product name
- (+)-Cloprostenol
- Purity
- ≥97%
- Packaging
- 10mg
- Price
- $565
- Updated
- 2024/03/01
- Product number
- CS-7779
- Product name
- (+)-Cloprostenol
- Purity
- 98.05%
- Packaging
- 25mg
- Price
- $936
- Updated
- 2021/12/16
- Product number
- API0006248
- Product name
- (+)-CLOPROSTENOL
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $972.63
- Updated
- 2021/12/16
(+)-Cloprostenol Chemical Properties,Usage,Production
Uses
(+)-Cloprostenol is a prostaglandin F2α (PGF2α) analogue, and shows selective agonistic activity at the prostaglandin receptor.
Definition
ChEBI: Cloprostenol is a prostanoid.
in vivo
D-cloprostenol (15 g per head) is the lowest dose that consistently achieves abortion; D-cloprostenol causes mild adverse effects including salivation, defecation and hyperventilation in bitches weighing less than 10 kg. Intra-vesicle administration of a single low dose of d-cloprostenol is a safe and successful technique to induce abortion in the bitch[1].
IC 50
PGF2α
References
[1] Manca R, et al. Intra-vesicle administration of D-cloprostenol for induction of abortion in mid-gestation bitches. Anim Reprod Sci. 2008 Jun;106(1-2):133-42. Epub 2007 Apr 21. DOI:10.1016/j.anireprosci.2007.04.011
[2] Re G, et al. Specific binding of dl-cloprostenol and d-cloprostenol to PGF2 alpha receptors in bovine corpus luteum and myometrial cell membranes. J Vet Pharmacol Ther. 1994 Dec;17(6):455-8. DOI:10.1111/j.1365-2885.1994.tb00277.x
(+)-Cloprostenol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (+)-Cloprostenol manufacturers
- Product
- (+)-Cloprostenol 54276-21-0
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 100kg
- Release date
- 2018-12-22