ChemicalBook > CAS DataBase List > Pregnenolone

Pregnenolone

Product Name
Pregnenolone
CAS No.
145-13-1
Chemical Name
Pregnenolone
Synonyms
5-Preg;ZK-5553;-20-one;prenolon;pregnolon;nen-3β-oL;Pregnelone;Progeserone;prenenolone;Arthenolone
CBNumber
CB1684326
Molecular Formula
C21H32O2
Formula Weight
316.48
MOL File
145-13-1.mol
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Pregnenolone Property

Melting point:
188-190 °C
alpha 
28.5 º (c=1, EtOH)
Boiling point:
395.89°C (rough estimate)
Density 
1.0382 (rough estimate)
refractive index 
1.5344 (estimate)
Flash point:
9℃
storage temp. 
Refrigerator
solubility 
ethanol: soluble10mg/mL, clear, colorless to faintly yellow
pka
15.00±0.70(Predicted)
form 
Powder
color 
White to off-white
Water Solubility 
41mg/L(room temperature)
Merck 
7733
BRN 
2059026
InChIKey
ORNBQBCIOKFOEO-QGVNFLHTSA-N
CAS DataBase Reference
145-13-1(CAS DataBase Reference)
NIST Chemistry Reference
Pregnenolone(145-13-1)
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Safety

Safety Statements 
22-24/25
RIDADR 
UN 1648 3 / PGII
WGK Germany 
3
RTECS 
TU5560700
HS Code 
29372900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P9129
Product name
5-Pregnen-3β-ol-20-one
Purity
≥98%
Packaging
1g
Price
$42.6
Updated
2021/03/22
Sigma-Aldrich
Product number
P-104
Product name
5-Pregnen-3β-ol-20-one
Purity
100 μg/mL in acetonitrile, certified reference material
Packaging
104-1ml
Price
$53.5
Updated
2020/08/18
Sigma-Aldrich
Product number
P-104
Product name
Pregnenolone solution
Purity
100?μg/mL in acetonitrile, certified reference material, Cerilliant?
Packaging
1 mL
Price
$55.2
Updated
2021/03/22
Cayman Chemical
Product number
19864
Product name
Pregnenolone
Purity
≥98%
Packaging
500mg
Price
$25
Updated
2021/03/22
Cayman Chemical
Product number
19864
Product name
Pregnenolone
Purity
≥98%
Packaging
1g
Price
$32
Updated
2021/03/22
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Pregnenolone Chemical Properties,Usage,Production

Description

Pregnenolone serves as the common precursor in the formation of the adrenocorticoids and other steroid hormones. This C21 steroid is converted via enzymatic oxidations and isomerization of the double bond to a number of physiologically active C21 steroids, including the female sex hormone progesterone and the adrenocorticoids hydrocortisone (cortisol), corticosterone, and aldosterone. Oxidative cleavage of the two-carbon side chain of pregnenolone and subsequent enzymatic oxidations and isomerization lead to C19 steroids, including the androgens testosterone and dihydrotestosterone. The final group of steroids, the C18 female sex hormones, are derived from oxidative aromatization of the A ring of androgens to produce estrogens.

Chemical Properties

white to off-white powder

Uses

glucocortcoid, antiinflammatory

Uses

Pregnenolone is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA an tagonist and increases neurogenesis in the hippocampus. It is a modulator of cytochrome P 450-3A

Definition

ChEBI: A 20-oxo steroid that is pregn-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 20.

Pregnenolone Preparation Products And Raw materials

Raw materials

Preparation Products

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Pregnenolone Suppliers

-Jiangsu Yuanda Xinyi Pharmaceutical Co. LTD
Tel
0515-84383317-
Fax
0515-84383393
Email
17723952475@163.com
Country
China
ProdList
1
Advantage
58
ChemCell Biomedicine Co.,Ltd.
Fax
0086-0757-85406358
Email
chemcell@hotmail.com;chemcell@hotmail.com
Country
China
ProdList
209
Advantage
52
Shaanxi billion Kang Long biological technology co., LTD
Tel
Fax
4009024560
Email
997832940@qq.com
Country
China
ProdList
315
Advantage
58
Hubei Nordina Biotechnology Co., Ltd.
Tel
135-54667548-
Fax
QQ:2729801554
Email
nuodina@163.com
Country
China
ProdList
2006
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Fax
86-21-61259102
Email
sh@meryer.com
Country
China
ProdList
40264
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15877
Advantage
69
Chembest Research Laboratories Limited
Tel
021-20908456-
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
5948
Advantage
61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
Beijing dtftchem Technology Co., Ltd.
Tel
13651141086; 86(10)60275028、60275820
Fax
86 (10) 60270825
Email
dtftchem@sina.com
Country
China
ProdList
3392
Advantage
62
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View Lastest Price from Pregnenolone manufacturers

WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
Product
Pregnenolone 145-13-1
Price
US $0.00/KG
Min. Order
100g
Purity
98%+
Supply Ability
100kg
Release date
2020-10-24
Hebei Crovell Biotech Co Ltd
Product
Pregnenolone 145-13-1
Price
US $10.50/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 ton
Release date
2021-06-29
Baoji Guokang Bio-Technology Co., Ltd.
Product
Pregnenolone 145-13-1
Price
US $412.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1T
Release date
2021-06-03

145-13-1, PregnenoloneRelated Search:


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