ChemicalBook > CAS DataBase List > (+)-Cloprostenol

(+)-Cloprostenol

Product Name
(+)-Cloprostenol
CAS No.
54276-21-0
Chemical Name
(+)-Cloprostenol
Synonyms
Superphan;cGMP Superphan;(+)-Cloprostenol;Cloprostenol Impurity 2;Cloprostenol in Acetonitrile;(+)-16-M-CHLOROPHENOXY TETRANOR PROSTAGLANDIN F2ALPHA;(+)-9ALPHA,11ALPHA,15-TRIHYDROXY-16-(3-CHLOROPHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;(Z)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-Chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoic acid;(5Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, (5Z)-
CBNumber
CB8467074
Molecular Formula
C22H29ClO6
Formula Weight
424.92
MOL File
54276-21-0.mol
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(+)-Cloprostenol Property

Boiling point:
628.0±55.0 °C(Predicted)
Density 
1.321
storage temp. 
Store at -20°C
solubility 
DMF: >100 mg/ml (from Fluprostenol); DMSO: >100 mg/ml (from Fluprostenol; Ethanol: >100 mg/ml (from Fluprostenol); PBS pH 7.2: >16 mg/ml (from Fluprostenol)
pka
4.76±0.10(Predicted)
form 
Oil
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16765
Product name
(+)-Cloprostenol
Purity
≥97%
Packaging
1mg
Price
$72
Updated
2024/03/01
Cayman Chemical
Product number
16765
Product name
(+)-Cloprostenol
Purity
≥97%
Packaging
5mg
Price
$319
Updated
2024/03/01
Cayman Chemical
Product number
16765
Product name
(+)-Cloprostenol
Purity
≥97%
Packaging
10mg
Price
$565
Updated
2024/03/01
ChemScene
Product number
CS-7779
Product name
(+)-Cloprostenol
Purity
98.05%
Packaging
25mg
Price
$936
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0006248
Product name
(+)-CLOPROSTENOL
Purity
95.00%
Packaging
10MG
Price
$972.63
Updated
2021/12/16
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(+)-Cloprostenol Chemical Properties,Usage,Production

Uses

(+)-Cloprostenol is a prostaglandin F2α (PGF2α) analogue, and shows selective agonistic activity at the prostaglandin receptor.

Definition

ChEBI: Cloprostenol is a prostanoid.

in vivo

D-cloprostenol (15 g per head) is the lowest dose that consistently achieves abortion; D-cloprostenol causes mild adverse effects including salivation, defecation and hyperventilation in bitches weighing less than 10 kg. Intra-vesicle administration of a single low dose of d-cloprostenol is a safe and successful technique to induce abortion in the bitch[1].

IC 50

PGF2α

References

[1] Manca R, et al. Intra-vesicle administration of D-cloprostenol for induction of abortion in mid-gestation bitches. Anim Reprod Sci. 2008 Jun;106(1-2):133-42. Epub 2007 Apr 21. DOI:10.1016/j.anireprosci.2007.04.011
[2] Re G, et al. Specific binding of dl-cloprostenol and d-cloprostenol to PGF2 alpha receptors in bovine corpus luteum and myometrial cell membranes. J Vet Pharmacol Ther. 1994 Dec;17(6):455-8. DOI:10.1111/j.1365-2885.1994.tb00277.x

(+)-Cloprostenol Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-Cloprostenol Suppliers

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View Lastest Price from (+)-Cloprostenol manufacturers

Career Henan Chemical Co
Product
(+)-Cloprostenol 54276-21-0
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
100kg
Release date
2018-12-22

54276-21-0, (+)-CloprostenolRelated Search:

(+)-Cloprostenol sodium 3-Methyl-2-buten-1-ol Maleic acid 3-SULFOLENE ENOLASE 2,2-Bis(hydroxymethyl)propionic acid Phosphoenolpyruvate carboxylase Polybutene Dihydromyrcenol Pregnenolone Fumaric acid CHLOROPHOSPHONAZO III CIS-BUTENEDIOIC ANHYDRIDE 1-BUTENE (±)-Cloprostenol sodium salt (+)-CLOPROSTENOL,CLOPROSTENOL,(+)-CLOPROSTENOL,CLOPROSTENOL 3-HEPTENOIC ACID (+)-Cloprostenol

  • (+)-9ALPHA,11ALPHA,15-TRIHYDROXY-16-(3-CHLOROPHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
  • (+)-16-M-CHLOROPHENOXY TETRANOR PROSTAGLANDIN F2ALPHA
  • Superphan
  • (+)-Cloprostenol
  • cGMP Superphan
  • (5Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid
  • (Z)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-Chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoic acid
  • 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, (5Z)-
  • Cloprostenol Impurity 2
  • Cloprostenol in Acetonitrile
  • 54276-21-0