4-BENZYLOXYPHENYLACETIC ACID METHYL ESTER
- Product Name
- 4-BENZYLOXYPHENYLACETIC ACID METHYL ESTER
- CAS No.
- 68641-16-7
- Chemical Name
- 4-BENZYLOXYPHENYLACETIC ACID METHYL ESTER
- Synonyms
- METHYL 4-BENZYLOXYPHENYLACETATE;methyl 2-(4-(benzyloxy)phenyl)acetate;methyl 2-(4-phenylmethoxyphenyl)acetate;4-BENZYLOXYPHENYLACETIC ACID METHYL ESTER;4-Benzyloxyphenylacetic Acid Methyl Ester,>97%;Benzeneacetic acid, 4-(phenylmethoxy)-, methyl ester
- CBNumber
- CB2698384
- Molecular Formula
- C16H16O3
- Formula Weight
- 256.3
- MOL File
- 68641-16-7.mol
4-BENZYLOXYPHENYLACETIC ACID METHYL ESTER Property
- Melting point:
- 53 °C
- Boiling point:
- 375.0±22.0 °C(Predicted)
- Density
- 1.129±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to light yellow Solid
- CAS DataBase Reference
- 68641-16-7(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- B130018
- Product name
- 4-BenzyloxyphenylaceticAcidMethylEster
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FB70559
- Product name
- 4-(Benzyloxyphenyl)acetic acid methyl ester
- Packaging
- 10g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FB70559
- Product name
- 4-(Benzyloxyphenyl)acetic acid methyl ester
- Packaging
- 25g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- 2639AL
- Product name
- 4-Benzyloxyphenylaceticacidmethylester
- Packaging
- 5g
- Price
- $145
- Updated
- 2021/12/16
- Product number
- FB70559
- Product name
- 4-(Benzyloxyphenyl)acetic acid methyl ester
- Packaging
- 100g
- Price
- $300
- Updated
- 2021/12/16
4-BENZYLOXYPHENYLACETIC ACID METHYL ESTER Chemical Properties,Usage,Production
Synthesis
14199-15-6
100-44-7
68641-16-7
To a suspension of acetone (50 mL) containing potassium carbonate (K2CO3, 20.7 g, 150 mmol) was sequentially added methyl 4-hydroxyphenylacetate (5.0 g, 30 mmol) and benzyl chloride (10.4 mL, 90 mmol). The reaction mixture was heated to reflux for 24 hours. Upon completion of the reaction, the mixture was cooled to room temperature, filtered to remove insoluble solids and the filtrate was concentrated. The residue was purified by silica gel column chromatography with 10% ethyl acetate/hexane as eluent to afford methyl 4-benzyloxyphenylacetate (7.7 g, 100% yield) as a white solid. Its 1H NMR (300 MHz, CDCl3) data were as follows: δ 7.40 (m, 5H), 7.21 (d, J = 6.6 Hz, 2H), 6.95 (d, J = 6.6 Hz, 2H), 5.05 (s, 2H), 3.70 (s, 3H), 3.59 (s, 2H).
References
[1] Patent: EP1218005, 2004, B1. Location in patent: Page 26
[2] Patent: WO2014/69963, 2014, A1. Location in patent: Paragraph 464-466
[3] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 4, p. 1209 - 1213
[4] Journal of Organic Chemistry, 1982, vol. 47, # 15, p. 2846 - 2851
[5] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 4, p. 525 - 528
4-BENZYLOXYPHENYLACETIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-BENZYLOXYPHENYLACETIC ACID METHYL ESTER manufacturers
- Product
- methyl2-(4-phenylmethoxyphenyl)acetate 68641-16-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99.2%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14
- Product
- 4-BENZYLOXYPHENYLACETIC ACID METHYL ESTER 68641-16-7
- Price
- US $8.00/KG
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- kg--tons
- Release date
- 2020-03-05