Camostat

Product Name: Camostat
CAS No.: 59721-28-7
Chemical Name: Camostat
Synonyms: FOY 305;CAMOSTAT;Camostatum;Ccris 7219;FOY-305：Foipan;Unii-0fd207wkdu;Camostat free base;Camostat formate salt;Camostatum [inn-latin];Camostat Monomethanesulfonate
CBNumber: CB4462187
Molecular Formula: C20H22N4O5
Formula Weight: 398.41
MOL File: 59721-28-7.mol

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Camostat Property

Boiling point:: 590.5±60.0 °C(Predicted)
Density: 1.28±0.1 g/cm3(Predicted)
pka: 10.17±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0010925
Product name: CAMOSTAT
Purity: 95.00%
Packaging: 5MG
Price: $502.48
Updated: 2021/12/16

AHH

Product number: MT-48918
Product name: Camostat
Purity: 98%
Packaging: 0.5g
Price: $910
Updated: 2021/12/16

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Camostat Chemical Properties,Usage,Production

Uses

Camostat is an orally active trypsin inhibitor. Camostat can reduce pancreatic fibrosis induced by repeated administration of superoxide dismutase inhibitors in rats, and decrease the proliferation and activation of pancreatic stellate cells (PSCs)[1].

Definition

ChEBI: Camostat is a benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients. It has a role as an anticoronaviral agent, a serine protease inhibitor, an antifibrinolytic drug, an anti-inflammatory agent, an antiviral agent, an antihypertensive agent and an antineoplastic agent. It is a tertiary carboxamide, a carboxylic ester, a diester, a member of guanidines and a benzoate ester. It is functionally related to a 4-guanidinobenzoic acid. It is a conjugate base of a camostat(1+).

References

[1] Emori Y, et al. Camostat, an oral trypsin inhibitor, reduces pancreatic fibrosis induced by repeated administration of a superoxide dismutase inhibitor in rats. J Gastroenterol Hepatol. 2005 Jun;20(6):895-9. DOI:10.1111/j.1440-1746.2005.03826.x

Camostat Preparation Products And Raw materials

Raw materials

Formyl chloride Triethylamine 4-Hydroxyphenylacetic acid 2-BROMOACETAMIDE Methyl bromide

Preparation Products

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Camostat Suppliers

China 37 Europe 1 India 3 Italy 1 United Kingdom 3 United States 7 Global 52

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
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Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19189
Advantage: 64

Shanghai SynFarm Pharmaceutical Technology Co., Ltd.

Tel: 021-50793966 18917198199
Fax: +86-21-50793967
Email: info@synfarm.com
Country: China
ProdList: 280
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Nanjing JinruiJiuAn Biotechnology Co., Ltd.

Tel: 025-58196018 800028039
Fax: 025-83453306
Email: sales@fartop.net
Country: China
ProdList: 2229
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China Nobel Chem Co., Limited

Tel: +86(0)21 60484900
Fax: +86(0)21 60484900
Country: China
ProdList: 764
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Linyi Shengxin Pharmaceutical R&D Co., Ltd

Tel: +86-18653953873
Fax: +86-539-2236091
Email: lysxyy@126.com
Country: China
ProdList: 26
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Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9650
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Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-+86-571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 11849
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Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
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Chizhou Kailong Import and Export Trade Co., Ltd.

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Email: xg01_gj@163.com
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59721-28-7, CamostatRelated Search:

CAMOSTAT MESYLATE,CAMOSTAT MESILATE 4-Methoxyphenylacetic acid 4-Hydroxyphenylacetic acid Carmofur 3-Dimethylaminopropylamine 2-Hydroxyphenylacetic acid Diethoxydimethylsilane Dimethyldimethoxysilane Carmustine Testosterone phenylacetate Phenylacetic acid 4-ETHOXYPHENYLACETIC ACID ETHYL 4-ETHOXYPHENYLACETATE 4-BENZYLOXYPHENYLACETIC ACID 2-(4-BENZYLOXYPHENYL)ETHANOL ETHYL 4-METHOXYPHENYLACETATE 4-BENZYLOXYPHENYLACETIC ACID METHYL ESTER Camostat

CAMOSTAT

4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneaxetic acid 2-(dimethylamino)-oxoethyl ester

Camostat (base and/or unspecified salts)

2-(Dimethylamino)-2-oxoethyl 4-(4-guanidinobenzoyloxy)phenylacetate

Camostat Monomethanesulfonate

FOY-305：Foipan

N，N-Dimethylcarbamoylmethyl-p(p-guanidinobenzoyloxy)phenylacetate

4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester

4-Guanidinobenzoic acid 4-[[[(dimethylcarbamoyl)methoxy]carbonyl]methyl]phenyl ester

4-Guanidinobenzoic acid-4-(dimethylcarbamoylmethoxycarbonylmethyl)phenyl ester

p-(p-Guanidinobenzoyloxy)phenylacetic acid=dimethylcarbamoylmethyl ester

59721-29-8 (Monomethanesulfonate)

Camostatum

Camostatum [inn-latin]

Ccris 7219

Dimethylcarbamoylmethyl 4-(4-guqnidinobenzoyloxy)phenylacetat

Unii-0fd207wkdu

2-{4-[(4-carbaMiMidaMidophenyl)carbonyloxy]phenyl}-3-(diMethylcarbaMoyl)propanoate

Benzeneacetic acid, 4-[[4-[(aMinoiMinoMethyl)aMino]benzoyl]oxy]-, 2-(diMethylaMino)-2-oxoethyl ester

FOY 305

4-[[4-[(aMinoiMinoMethyl)aMino]benzoyl]oxy]-, 2-(diMethylaMino)- 2-oxoethyl ester, MonoMethanesulfonate

4-(2-(2-(Dimethylamino)-2-oxoethoxy)-2-oxoethyl)phenyl 4-guanidinobenzoate

4-[2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl]phenyl]4-(diaminomethylideneamino)benzoate

Camostat formate salt

Camostat free base

59721-28-7

API