ChemicalBook > CAS DataBase List > Rhodamine 123

Rhodamine 123

Product Name
Rhodamine 123
CAS No.
62669-70-9
Chemical Name
Rhodamine 123
Synonyms
rh123;R 302;R 22420;RHODAMINE 123;-Cellstain-Rh123;Rhodamine 123 ,98%;Rhodamine 123, 99+%;Rhodamine 123, pure;Rhodamine 123 (RH-123;Rhodamine 123 (Green)
CBNumber
CB2702364
Molecular Formula
C21H17ClN2O3
Formula Weight
380.83
MOL File
62669-70-9.mol
More
Less

Rhodamine 123 Property

Melting point:
235 °C
Density 
1.2224 (rough estimate)
refractive index 
1.6500 (estimate)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
ethanol: 20 mg/mL, clear, red
form 
Powder
color 
Red-brown to brown or dark green
Appearance
brown crystals
Water Solubility 
Partially soluble
λmax
501 nm, 507 nm
BRN 
6030951
Stability:
Hygroscopic
Major Application
Colored bubbles; color filters; liquid crystal displays; light-emitting diodes; luminescent materials;nanophotonic composites; paints; semiconductor electrodes;solar cells
Biological Applications
Measuring membrane potential; detecting cancer cells,spores,prostate cancer,stress biomarkers; treating disc degenerative disease,epilepsy,erectile dysfunction; apoptosis assays; tumor cell multidrug resistance assay; implantable
InChIKey
MYFATKRONKHHQL-UHFFFAOYSA-N
CAS DataBase Reference
62669-70-9(CAS DataBase Reference)
EPA Substance Registry System
Xanthylium, 3,6-diamino-9-[2-(methoxycarbonyl)phenyl]-, chloride (62669-70-9)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
ZE0883000
HS Code 
32049010
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R8004
Product name
Rhodamine 123
Purity
mitochondrial specific fluorescent dye
Packaging
5mg
Price
$40.9
Updated
2025/07/31
Sigma-Aldrich
Product number
R8004
Product name
Rhodamine 123
Purity
mitochondrial specific fluorescent dye
Packaging
25mg
Price
$159
Updated
2025/07/31
Cayman Chemical
Product number
16672
Product name
Rhodamine 123 (chloride)
Purity
≥95%
Packaging
5mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
16672
Product name
Rhodamine 123 (chloride)
Purity
≥95%
Packaging
10mg
Price
$57
Updated
2024/03/01
Sigma-Aldrich
Product number
R8004
Product name
Rhodamine 123
Purity
mitochondrial specific fluorescent dye
Packaging
100mg
Price
$444
Updated
2025/07/31
More
Less

Rhodamine 123 Chemical Properties,Usage,Production

Description

Rhodamine 123 is a membrane-permeable cationic dye that is readily accumulated within living cells. It is a substrate for the efflux pump P-glycoprotein (P-gp; also known as multidrug resistance protein 1 and ABCB1) and is rapidly exported from cells with functional P-gp. As P-gp is expressed on a population of stem cells known as the side population, rhodamine 123 is used to detect this group of stem cells. Rhodamine 123 also accumulates within mitochondria due to its positive charge and can inhibit oxidative phosphorylation. Rhodamine 123 has excitation/emission maxima of 507/529 nm.

Chemical Properties

red-brown to brown or dark green powder

Uses

Rhodamine derivative, a fluoresent dye-labeled compound.

Uses

Fluorescent dye most commonly used as functional reporter in flow cytometry.

Uses

Useful as a laser dye and to have selective cell growth effects. Mitochondrial specific fluorescent dye and substrate for P-glycoprotein.

Uses

Rhodamine-123 is a fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Rhodamine 123 (R123), as a typical of P-glycoprotein substrate, was widely used to quantify P-glycoprotein (P-gp) functional efflux activity in vivo. Rhodamine-123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid).

Uses

Rhodamine-123 lycoprotein (P-gp) functional efflux activity in vivo. Rhodamine-123 PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid).

in vitro

rhodamine 123, which was identified as a member of the rhodamine family of flurone dyes, was used to examine membrane transport by the abcb1 gene product, mdr1. previous study determined the λmax for excitation and emission for rhodamine 123 in commonly used solvents and extraction buffers, indicating that the fluorescence of rhodamine 123 was highly dependent on the chemical environment. the optimal parameters are 1% methanol in hbss. in addition, the uptake of rhodamine 123 into cells was via both passive and active processes, and this occurred mainly by oatp1a2-mediated transport. furthermore, this previous study quantified the intracellular sequestration and metabolism of rhodamine 123, showing that these were both cell line-dependent factors that might influence the interpretation of transport assays [1].

References

[1] samantha forster et al. characterization of rhodamine-123 as a tracer dye for use in in vitro drug transport assays. plos one. 2012; 7(3): e33253.

Abs/Em Maxima

511/531 nm

Excitation / Emission Maximum

507 nm/529 nm

Fluoresene quantum yield

0.98

Extinction Coefficient

86000

Rhodamine 123 Preparation Products And Raw materials

Raw materials

FUMING SULFURIC ACID Sodium chloride Acetyl chloride Trimellitic Anhydride Ethyl acetate Phthalic anhydride Hydrochloric acid Dichloromethane Methanol 3-Aminophenol Sulfuric acid Ammonia

Preparation Products

More
Less

Rhodamine 123 Suppliers

Belgium 1 Canada 1 China 289 Europe 2 Germany 3 India 3 Japan 4 Switzerland 4 Ukraine 1 United Kingdom 3 United States 27 Global 338
Guangzhou City Haizhu District Zhenghong Co.Ltd.
Tel
020-82550624 13016020539
Fax
020-82571650
Email
2336504938@qq.com
Country
China
ProdList
409
Advantage
58
Okeanos Tech Co,. Ltd.
Tel
010-62651721 18610486005
Fax
01062651521-808
Email
minghui.yu@okeanos.com.cn
Country
China
ProdList
495
Advantage
60
Beijing Institute of Coollight Fine Chemicals
Tel
010-86-10-69293631 13910082894
Fax
86-10-69242496
Email
1918474247@qq.com
Country
China
ProdList
191
Advantage
58
Changsha Hanchen Biotechnology Co., LTD
Tel
18175992585
Email
luohuichao@hanchbio.cn
Country
China
ProdList
294
Advantage
58
Nanjing UltraPure Biotech Co., Ltd.
Tel
025-82263158 13851993283
Fax
025-82263168
Email
2842979086@qq.com
Country
China
ProdList
241
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Beijing HwrkChemical Technology Co., Ltd
Tel
18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9400
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Beijing VSciChem Technology Co., Ltd.
Tel
13811761079
Email
vscichem@163.com
Country
China
ProdList
263
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16077
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
7247
Advantage
62
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4747
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4999
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Shanghai Ruji Biology Technology Co., Ltd.
Tel
+86-21-65211385-8001 36031160
Fax
+86-21-65211385-8004
Email
sales@shruji.com
Country
China
ProdList
3224
Advantage
55
Shanghai Run-Biotech Co., Ltd.
Tel
021-57171705 13817537615
Fax
QQ3095748324
Email
sales@run-biotech.com
Country
China
ProdList
2332
Advantage
58
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3921
Advantage
50
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15873
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
6687
Advantage
55
Nanjing XiLang Chemical Products Co., Ltd.
Tel
18936048580
Email
chemxilang@163.com
Country
China
ProdList
3909
Advantage
58
Shanghai Changyan Chem & Tech Co., Ltd.
Tel
021-20242659 18930833303
Fax
+86 (21) 2024-2659
Email
Sales@changyanchem.cn
Country
China
ProdList
5001
Advantage
55
Raw material medicin reagent co.,Ltd
Tel
Email
sales@njromanme.com
Country
China
ProdList
4529
Advantage
58
Beijing Hechemist Technology CO.,LTD
Tel
18511709189
Fax
010-58043593
Email
sales@hechemist.com
Country
China
ProdList
2835
Advantage
58
Shanghai Rechem science Co., Ltd.
Tel
021-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2991
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9125
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 18101056239
Email
3193328036@qq.com
Country
China
ProdList
29759
Advantage
68
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886750 13927877953
Fax
0751-2886750
Email
3005811397@qq.com
Country
China
ProdList
13305
Advantage
58
Shanghai Civic Chemical Technology Co., Ltd.
Tel
021-34053660
Fax
QQ:2881074831
Email
sale2@labgogo.com
Country
China
ProdList
2018
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Shanghai Yihe Biological Technology Co., Ltd.
Tel
021-68882955 17721395025
Fax
021-68882955
Email
2423903095@qq.com
Country
China
ProdList
4992
Advantage
58
Medi-tech Bioscientific Co., Ltd.
Tel
0519-83246372 13585352506
Fax
0519-83246372
Country
China
ProdList
1844
Advantage
58
Zhengzhou Huiju Chemical Co., Ltd.
Tel
0371-55900031 18137872243
Fax
QQ：2853979815
Email
2853979815@qq.com
Country
China
ProdList
9996
Advantage
55
Changzhou Jiezhan Chemical Technology Co., Ltd
Tel
15861130028; 15861130028
Email
956912955@qq.com
Country
China
ProdList
296
Advantage
58
Heze Development Zone chuangli Chemical Co., Ltd.
Tel
0530-+86-530-529 6766，+86-15666160102 15666160102
Fax
0530-529 6766
Email
info@chuangli-chem.com
Country
China
ProdList
836
Advantage
55
JinJin Le Chemical Co., Ltd
Tel
18001959627(微信同号) 18001959627
Email
jjlchem2@163.com
Country
China
ProdList
9981
Advantage
58
More
Less

View Lastest Price from Rhodamine 123 manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Rhodamine 123 62669-70-9
Price
US $0.10/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10
Release date
2024-08-04
Career Henan Chemical Co
Product
Rhodamine 123 62669-70-9
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
1000kg
Release date
2018-12-25

62669-70-9, Rhodamine 123Related Search:

Ammonium chloride Sulforhodamine B RHODAMINE 110 Rhodamine B Rhodamine 6G PHENYL VALERATE Sodium chloride Choline chloride Calcium chloride Polyvinyl chloride Rhodamine 101 chloride Potassium chloride Rhodamine 700 Rhodamine 101 inner salt, pure, 99% 9-Cyano-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium perchlorate 9-(2-carboxyphenyl)-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium perchlorate RHODAMINE 19 PERCHLORATE RHODAMINE 19

  • Rhodamine methyl ester hydrochloride
  • Rhodamin 123 Chloride, laser grade
  • 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester monohydrochloride
  • Benzoic acid, 2-(6-amino-3-imino-3H-xanthen-9-yl)-, methyl ester, monohydrochloride
  • Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-, chloride
  • Rhodamine 123 ,98%
  • RHODAMINE 123, 99+%, PURE
  • Rhodamine 123, pure
  • Rhodamine 123,2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester
  • RhodaMine 123 Chloride, Laser Grade
  • Rhodamine 123, 99+%
  • 2-[6-AMINO-3-IMINO-3H-XANTHEN-9-YL]BENZOIC ACID METHYL ESTER
  • 2-(6-AMINO-3-IMINO-3H-XANTHEN-9-YL)BENZOIC ACID METHYL ESTER CHLORIDE
  • RHODAMINE METHYL ESTER CHLORIDE
  • R 22420
  • R 302
  • Rhodamine 123 *CAS 62669-70-9*
  • Rhodamine 123 Chloride
  • RHODAMINE 123, FOR FLUORESCENCE
  • -Cellstain-Rh123
  • Rhodamine 123, pure, 99+%
  • RHODAMINE 123
  • RHODAMINE 123 HYDROCHLORIDE
  • 2-(6-amino-3-imino-3h-xanthen-9-yl)benzoicacidmethylestermonohydrochlorid
  • 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-xanthyliuchloride
  • 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)xanthyliumchloride
  • benzoicacid,2-(6-amino-3-imino-3h-xanthen-9-yl)-,methylester,monohydroch
  • rh123
  • Rhodamine 123 (RH-123
  • 3,6-DIAMINO-9-[2-(METHOXYCARBONYL)PHENYL]-10???XANTHEN-10-YLIUM CHLORIDE
  • Rhodamine 123 (Green)
  • 62669-70-9
  • C21H17N2O3Cl
  • C28H24N4O10S
  • C21H16N2O3HCl
  • C21H17ClN2O3
  • Fluorescent Probes, Labels, Particles and Stains
  • Fluorescent Indicators and Probes
  • Alphabetical
  • Lipophilic and Membrane Probes
  • Biochemicals and Reagents
  • BioChemical
  • Xanthene
  • Amines
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Fluorescent Labels & Indicators
  • ROX