HARRINGTONINE

Product Name: HARRINGTONINE
CAS No.: 26833-85-2
Chemical Name: HARRINGTONINE
Synonyms: HT;nsc124147;(3(r))-ter;HARRINGTONIN;HARRINGTONINE;2'R-HARRINGTONINE;HARRINGTONINE98%,99%;Harringtonine 26833-85-2;alkaloidcfromcephalotaxus;HARRINGTONINE(P) USP/EP/BP
CBNumber: CB2702955
Molecular Formula: C28H37NO9
Formula Weight: 531.6
MOL File: 26833-85-2.mol

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HARRINGTONINE Property

Melting point:: 73～75℃
Boiling point:: 679.4±55.0 °C(Predicted)
Density: 1.35±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form: A crystalline solid
pka: 11.62±0.29(Predicted)
color: White to light yellow

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Safety

RIDADR: 1544
HazardClass: 6.1(a)
PackingGroup: II

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H310Fatal in contact with skin

H330Fatal if inhaled

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P350IF ON SKIN: Gently wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P310Immediately call a POISON CENTER or doctor/physician.

P320Specific treatment is urgent (see … on this label).

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 15361
Product name: Harringtonine
Purity: ≥95%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 15361
Product name: Harringtonine
Purity: ≥95%
Packaging: 5mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 15361
Product name: Harringtonine
Purity: ≥95%
Packaging: 10mg
Price: $172
Updated: 2024/03/01

Usbiological

Product number: 300401
Product name: Harringtonine
Packaging: 20mg
Price: $335
Updated: 2021/12/16

TRC

Product number: H105285
Product name: Harringtonin
Packaging: 10mg
Price: $150
Updated: 2021/12/16

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HARRINGTONINE Chemical Properties,Usage,Production

Description

The full structure of harringtonine has now been established from a study of the hydrolysis products of this base.

Description

Harringtonine is a natural alkaloid that inhibits protein synthesis at low micromolar concentrations. It immobilizes ribosomes immediately after the initiation of translation. While harringtonine has drawn some interest in mitigating cancer, its homolog homoharrington is more effective, particularly for chronic myelogenous leukemia. The ability of harringtonine to immobilize initiating ribosomes can be used to capture ribosome-protected mRNA fragments for evaluating translation.

Chemical Properties

White Solid

Uses

A natural product with significant antitumor activities.

Uses

specific anti-leukemia drug

Definition

ChEBI: Harringtonine is an alkaloid.

References

Mikolajczak, Powell, Smith, Tetrahedron, 28, 1995 (1972)
Kelly, McKenna, Christenson, Tetrahedron Lett., 35m (1973)

HARRINGTONINE Preparation Products And Raw materials

Raw materials

Preparation Products

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HARRINGTONINE Suppliers

Canada 1 China 121 Germany 2 India 2 Japan 1 United Kingdom 9 United States 29 Global 165

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View Lastest Price from HARRINGTONINE manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.

Product: HARRINGTONINE 26833-85-2
Price: US $0.00-0.00/mg
Min. Order: 20mg
Purity: 98% HPLC
Supply Ability: 100kg
Release date: 2022-10-21

Shanghai Standard Technology Co., Ltd.

Product: Harringtonine 26833-85-2
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥95%(HPLC)
Supply Ability: 10 g
Release date: 2019-11-26

NanJing Spring & Autumn Biological Engineering CO., LTD.

Product: Harringtonine 26833-85-2 26833-85-2
Price: US $80.00/mg
Min. Order: 20mg
Purity: ≥98%
Supply Ability: 1000.00 kgs
Release date: 2019-07-03

26833-85-2, HARRINGTONINERelated Search:

PHENTERMINE N-Methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine LACTIC ACID ISOAMYL ESTER Dimethyl malate AMYL-2-METHYLBUTYRATE HARRINGTONINE FEMA 3505 propyl 2-methylpentanoate 1-(3,4-Methylenedioxyphenyl)-2-butanamine (R)-(-)-1-OCTEN-3-OL, 99 HT-2,Toxin HT 2,Mycotoxin HT 2 arquad2h unistoncr-ht20 Araldite HT 907 Araldite HT 901,Ht 901 b-ht92 Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)-, hydrolysis products with silica HARRINGTONINE(P)

(3(r))-ter

4-methyl-cephalotaxin2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioate(es

alkaloidcfromcephalotaxus

cephalotaxine,4-methyl(2r)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioat

nsc124147

HARRINGTONIN

HARRINGTONINE

HT

2'R-HARRINGTONINE

Cephalotaxine, 4-methyl (2R)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioate (ester)

HARRINGTONINE98%,99%

2’R-Harringtonine,Harringtonin

Harringtonine, 98%, from Taxus chinensis (Pilg.) Rehder

3-[4-Methyl (2R)-2-hydroxy-2-(3-hydroxy-3-Methylbutyl)butanedioate]cephalotaxine

3-methylbutyl)butanedioate (ester), [3(R)]-

Cephalotaxine, 4-methyl 2-hydroxy-2-(3-hydroxy-

2-Hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioic acid 1-[(3R)-3-deoxycephalotaxin-3-yl]4-methyl ester

Harringtonine 26833-85-2

Cephalotaxine, 3-[4-methyl (2R)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioate]

HARRINGTONINE(P) USP/EP/BP

(R)-1-((11bS,12S,14aR)-13-Methoxy-2,3,5,6,11b,12-hexahydro-1H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]cyclopenta[b]pyrrolo[1,2-a]azepin-12-yl) 4-methyl 2-hydroxy-2-(3-hydroxy-3-methylbutyl)succinate

26833-85-2

C28H37NO9

Intermediates & Fine Chemicals

Pharmaceuticals

Alkaloids