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5-Nitrofurfural

Product Name
5-Nitrofurfural
CAS No.
698-63-5
Chemical Name
5-Nitrofurfural
Synonyms
5-NITRO-2-FURALDEHYDE;AKOS B004244;Nitrofurfural;5-Nitrofurural;5-nitro-furfura;5-NITROFURFURAL;Furfural, 5-nitro-;5-NITROFURALDEHYDE;Niftyer Impurity 7;Nitrofuraldehyde,97%
CBNumber
CB2711562
Molecular Formula
C5H3NO4
Formula Weight
141.08
MOL File
698-63-5.mol
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5-Nitrofurfural Property

Melting point:
37-39 °C(lit.)
Boiling point:
121 °C10 mm Hg(lit.)
Density 
1.349 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.59(lit.)
Flash point:
92 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
form 
Crystalline Low Melting Solid
color 
Yellow to brown
Water Solubility 
sparingly soluble
Sensitive 
Air & Light Sensitive
BRN 
120539
InChIKey
SXINBFXPADXIEY-UHFFFAOYSA-N
CAS DataBase Reference
698-63-5(CAS DataBase Reference)
NIST Chemistry Reference
2-Furancarboxaldehyde, 5-nitro-(698-63-5)
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Safety

Hazard Codes 
F,Xi,Xn
Risk Statements 
11-68-10
Safety Statements 
16-36/37
RIDADR 
UN 1325 4.1/PG 2
WGK Germany 
3
RTECS 
LT7200000
Hazard Note 
Irritant
HazardClass 
3.2
PackingGroup 
III
HS Code 
29321900
Hazardous Substances Data
698-63-5(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H228Flammable solid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
170968
Product name
5-Nitro-2-furaldehyde
Purity
99%
Packaging
5g
Price
$85
Updated
2024/03/01
Sigma-Aldrich
Product number
170968
Product name
5-Nitro-2-furaldehyde
Purity
99%
Packaging
25g
Price
$163
Updated
2024/03/01
TCI Chemical
Product number
N0387
Product name
5-Nitro-2-furaldehyde
Purity
>98.0%(GC)
Packaging
5g
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
N0387
Product name
5-Nitro-2-furaldehyde
Purity
>98.0%(GC)
Packaging
25g
Price
$105
Updated
2024/03/01
Alfa Aesar
Product number
A10618
Product name
5-Nitro-2-furaldehyde, 99%
Packaging
25g
Price
$133
Updated
2024/03/01
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5-Nitrofurfural Chemical Properties,Usage,Production

Description

Nitrofuran carboxaldehyde (NFC) is used to synthesize many drugs and chemicals such as nifuraldezone, puraguanidine, nifuratrone, furmethoxadone, etc. Furfural the main structure of NFC was determined many years ago to be a byproduct of formic acid synthesis. Furfural is produced from agricultural byproducts such as sugarcane bagasse and corncobs.

Chemical Properties

Yellow to brown crystalline low melting solid

Uses

NFC and its derivatives have antibacterial and antifungal activities. They destroy both gram-positive and gram-negative organisms such as Staphylococcus aureus, Salmonella schotmuelleri, Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli, and Streptococcus pyogenes. They may be used as antibacterial agents in a prophylactic manner, for example, in cleaning and disinfecting products. This compound also has antitrichomonal and antifungal activities.

Uses

5-Nitro-2-furaldehyde was used in the synthesis of a series of 4-(5-nitrofuran-2-yl)prop-2-en-1-one derivatives. . It was also used in the synthesis of modified mesoporous silica (MCM-41). 5-Nitrofurfural can be commonly used as pharmaceutical intermediates.

Definition

ChEBI: 5-Nitrofurfural is a C-nitro compound and a member of furans.

Production Methods

Furfural is nitrated in acetic anhydride solution at 25 – 40 ℃ to give the diacetate [92-55-7], which is purified by recrystallization from isopropanol and then used directly for the production of derived drugs.

Toxicity evaluation

NFC inhibits the uptake of oxygen and disrupts cellular respiration within mitochondria. NFC and other nitrofurans are relatively potent inhibitors of monoamine oxidase enzyme in mammalian and avian species.

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5-Nitrofurfural Suppliers

Nantong Zandery Biotechnology Co., Ltd.
Tel
0513-87582998 13912206938
Fax
+86 (513) 87581996
Email
xiaofeizhu@vip.163.com
Country
China
ProdList
306
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
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View Lastest Price from 5-Nitrofurfural manufacturers

Career Henan Chemical Co
Product
5-Nitrofurfural 698-63-5
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 605
Release date
2019-09-01
Career Henan Chemical Co
Product
5-Nitrofurfural 698-63-5
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 621
Release date
2019-09-01

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