FMOC-ASP-ODMAB

Product Name: FMOC-ASP-ODMAB
CAS No.: 172611-77-7
Chemical Name: FMOC-ASP-ODMAB
Synonyms: FMOC-ASP-ODMAB;Fmoc-L-Asp-ODmab;FMOC-ASP-ODMAB 5 G;(9H-Fluoren-9-yl)MethOxy]Carbonyl Asp-ODmab;Fmoc-L-aspartic acid α-4-[N-{1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl}amino]benzyl ester;Fmoc-L-aspartic acid alpha-4-[N-{1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl}amino]benzyl ester;FMOC-L-ASPARTIC ACID ALPHA-4-[N-[1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEXYLIDENE)-3-METHYLBUTYL]AMINO]BENZYL ESTER;N-ALPHA-FMOC-L-ASPARTIC ACID ALPHA-4-[N-[1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEXYLIDENE)-3-METHYLBUTYL]-AMINO] BENZYL ESTER;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-aspartic acid 1-[[4-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]phenyl]methyl] ester;L-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 1-[[4-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]phenyl]methyl] ester
CBNumber: CB2713809
Molecular Formula: C39H42N2O8
Formula Weight: 666.76
MOL File: Mol file

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FMOC-ASP-ODMAB Property

Boiling point:: 838.4±65.0 °C(Predicted)
Density: 1.264±0.06 g/cm3(Predicted)
storage temp.: Store at -15°C to -25°C.
pka: 4.01±0.19(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.52079
Product name: Fmoc-Asp-ODmab
Purity: Novabiochem?
Packaging: 1G
Price: $264
Updated: 2023/06/20

Sigma-Aldrich

Product number: 8.52079
Product name: Fmoc-Asp-ODmab
Purity: Novabiochem?
Packaging: 5G
Price: $1050
Updated: 2023/06/20

Chem-Impex

Product number: 03693
Product name: Fmoc-L-asparticacidα-4-[N-{1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl}amino]benzylester,98%(HPLC)
Purity: 98%(HPLC)
Packaging: 25G
Price: $2144.8
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0006777
Product name: FMOC-ASP-ODMAB
Purity: 95.00%
Packaging: 5MG
Price: $503.1
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0006777
Product name: FMOC-ASP-ODMAB
Purity: 95.00%
Packaging: 250MG
Price: $594
Updated: 2021/12/16

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FMOC-ASP-ODMAB Chemical Properties,Usage,Production

Chemical Properties

FMOC-ASP-ODMAB is Yellow powder

Uses

The Dmab group can be cleaved selectively in the presence of tBu-based protected groups by treatment with 2% hydrazine in DMF, making this derivative an extremely useful tool for the preparation of cyclic peptides by FMOC SPPS

General Description

Quasi-orthogonally-protected Asp derivative.

The Dmab group can be removed selectively in the presence of tBu-based protecting groups by treatment with 2% hydrazine in DMF [1], making this derivative an extremely useful tool for the preparation of cyclic peptides by Fmoc SPPS or for library synthesis.

Occasionally sluggish cleavage of the aminobenzyl moiety is observed [2, 3]. In these instances, washing the support with 20% DIPEA in DMF/water (9:1) [2] or HCl in dioxane [4] has been found to be efficacious.

For the on-resin synthesis of side-chain to side-chain lactam bridged peptides, the combination of Lys(ivDde) and Asp(ODmab) is particularly advantageous since both side-chains can be simultaneously unmasked in a single step.

To avoid aspartimide formation, it is advisable to employ an Hmb- or Dmb-protected derivative for introduction of the preceding residue.

For applications of this derivative in the synthesis of cyclic peptides, see references [5 - 7].

The product number for this product was previously 04-12-1176.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

FMOC-ASP-ODMAB Preparation Products And Raw materials

Raw materials

Preparation Products

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FMOC-ASP-ODMAB Suppliers

China 38 Japan 1 United Kingdom 1 United States 6 Global 46

Alabiochem Tech.Co., Ltd.

Tel: 0512-58900862 400-0707518
Fax: 0086-512-56765862
Email: sales@alabiochem.com
Country: China
ProdList: 995
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GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Shenzhen Chim Biotech Co., Ltd.

Tel: 0755-36320761 13692196024
Fax: 0755-28364769
Email: sales@chimchem.com
Country: China
ProdList: 501
Advantage: 55

Shanghai GL Peptide Ltd.

Tel: +86-21-61263310; 13764994101 13764994101
Fax: 021-61263399
Email: fisherwang@glschina.com
Country: China
ProdList: 8462
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Alabiotech Inc.

Tel: 001-619-354-5251
Fax: 001-855-855-6087
Email: sales@alabiotech-e.com
Country: United States
ProdList: 972
Advantage: 60

Wuxi Asia Peptide Biotechnology Limited Company

Tel: 0510-83583050 13771062561
Fax: 0510-83583039
Email: willsun@peptide-search.com
Country: China
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Nanjing Peptide Biotech Ltd.

Tel: 025-025-58361106-805-805 13082558573
Fax: 025-58361106-806
Email: liugang@njpeptide.com
Country: China
ProdList: 9962
Advantage: 55

Alpha Biopharmaceuticals Co., Ltd

Tel: +86-411-39042497 +8613921981412
Fax: 0086-411-39042693
Email: sales@alphabiopharm.com
Country: China
ProdList: 886
Advantage: 58

Alpha Biopharmaceuticals Co., Ltd

Tel: 0411-39042497
Fax: 0411-39042693
Email: sales@alphabiopharm.com
Country: China
ProdList: 1951
Advantage: 58

172611-77-7, FMOC-ASP-ODMABRelated Search:

L-Cysteine Fmoc-L-aspartic acid

(3S)-4-[(4-{[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino}phenyl)methoxy]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-oxobutanoic acid

(S)-3-(((9H-fluoren-9-yl)methyl9H-fluoren-9-yl)methoxy)carbonylamino)-4-(4-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutylamino)benzyloxy)-4-oxobutanoic acid

Fmoc-L-aspartic acid alpha-4-[N-{1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl}amino]benzyl ester

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-aspartic acid 1-[[4-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]phenyl]methyl] ester

Fmoc-L-Asp-ODmab

N-ALPHA-FMOC-L-ASPARTIC ACID ALPHA-4-[N-[1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEXYLIDENE)-3-METHYLBUTYL]-AMINO] BENZYL ESTER

FMOC-L-ASPARTIC ACID ALPHA-4-[N-[1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEXYLIDENE)-3-METHYLBUTYL]AMINO]BENZYL ESTER

FMOC-ASP-ODMAB

(9H-Fluoren-9-yl)MethOxy]Carbonyl Asp-ODmab

FMOC-ASP-ODMAB 5 G

Fmoc-L-aspartic acid α-4-[N-{1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl}amino]benzyl ester

(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-((4-((1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl)amino)benzyl)oxy)-4-oxobutanoic acid

L-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 1-[[4-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]phenyl]methyl] ester

172611-77-7