ChemicalBook > CAS DataBase List > 2-BROMO-1-BENZOFURAN

2-BROMO-1-BENZOFURAN

Product Name
2-BROMO-1-BENZOFURAN
CAS No.
54008-77-4
Chemical Name
2-BROMO-1-BENZOFURAN
Synonyms
2-BROMOBENZOFURAN;Benzofuran, 2-broMo-;2-Bromobenzo[b]furan;2-BROMO-1-BENZOFURAN;2-bromobenzofuran-D5;2-Bromo-1-benzofurane;2-Bromobenzo[b]furan 90%;2-Bromo-1-benzofuran, 90+%;2-Bromo-1-benzofuran:2-bromobenzofuran
CBNumber
CB2721954
Molecular Formula
C8H5BrO
Formula Weight
197.03
MOL File
54008-77-4.mol
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2-BROMO-1-BENZOFURAN Property

Melting point:
247-247.5 °C
Boiling point:
234℃
Density 
1.608
Flash point:
95℃
storage temp. 
Sealed in dry,Store in freezer, under -20°C
Appearance
Colorless to light yellow Liquid
InChI
InChI=1S/C8H5BrO/c9-8-5-6-3-1-2-4-7(6)10-8/h1-5H
InChIKey
RNEOFIVNTNLSEH-UHFFFAOYSA-N
SMILES
O1C2=CC=CC=C2C=C1Br
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Safety

HS Code 
2932990090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B678388
Product name
2-Bromo-1-benzofuran
Packaging
500mg
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB42238
Product name
2-Bromobenzofuran
Packaging
250mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB42238
Product name
2-Bromobenzofuran
Packaging
500mg
Price
$90
Updated
2021/12/16
AK Scientific
Product number
W6833
Product name
2-Bromobenzofuran
Packaging
250mg
Price
$101
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB42238
Product name
2-Bromobenzofuran
Packaging
1g
Price
$128
Updated
2021/12/16
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2-BROMO-1-BENZOFURAN Chemical Properties,Usage,Production

Synthesis

91703-34-3

54008-77-4

2-(2,2-dibromovinyl)phenol (2.8 g, 10 mmol) was dissolved in tetrahydrofuran (30 mL) under nitrogen protection. Subsequently, cuprous iodide (I) (0.1 g, 0.5 mmol) and potassium phosphate (4.2 g, 20 mmol) were added. The reaction mixture was stirred at 80°C for 12 hours. After completion of the reaction, the mixture was poured into water (200 mL) and extracted with ethyl acetate (200 mL). The organic phases were combined, dried over anhydrous sodium sulfate and filtered. The filtrate was concentrated and purified by column chromatography (silica gel, eluent ethyl acetate/petroleum ether=1:20) to afford the target product 2-bromobenzofuran (1.8 g, 92% yield).

References

[1] Tetrahedron, 2011, vol. 67, # 33, p. 5913 - 5919
[2] Chemical Communications, 2011, vol. 47, # 37, p. 10476 - 10478
[3] Organic and Biomolecular Chemistry, 2013, vol. 11, # 24, p. 4095 - 4101
[4] Organic and Biomolecular Chemistry, 2012, vol. 10, # 21, p. 4172 - 4178
[5] Chemistry - A European Journal, 2015, vol. 21, # 4, p. 1482 - 1487

2-BROMO-1-BENZOFURAN Preparation Products And Raw materials

Raw materials

Preparation Products

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2-BROMO-1-BENZOFURAN Suppliers

Zhejiang Zetian Fine Chemical Co., Ltd.
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0571-87682782 18957127338
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sales@zetchem.com
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J & K SCIENTIFIC LTD.
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Bide Pharmatech Ltd.
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View Lastest Price from 2-BROMO-1-BENZOFURAN manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
2-BROMO-1-BENZOFURAN 54008-77-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-27
Career Henan Chemical Co
Product
2-BROMO-1-BENZOFURAN 54008-77-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-07