ChemicalBook > CAS DataBase List > 1,2-Distearoyl-sn-glycero-3-phosphocholine

1,2-Distearoyl-sn-glycero-3-phosphocholine

Product Name
1,2-Distearoyl-sn-glycero-3-phosphocholine
CAS No.
816-94-4
Chemical Name
1,2-Distearoyl-sn-glycero-3-phosphocholine
Synonyms
DSPC;1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE;1,2-Distearoyl-sn-glycero-3-PC;(R)-2,3-Bis(stearoyloxy)propyl (2-(triMethylaMMonio)ethyl) phosphate;1,2-Dioctadecanoyl-sn-glycero-3-phophocholine;1,2-DIOCTADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;18:0 PC;1,2-DSPC;DSPC(18:0);DSPC L-1118
CBNumber
CB2724667
Molecular Formula
C44H88NO8P
Formula Weight
790.15
MOL File
816-94-4.mol
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1,2-Distearoyl-sn-glycero-3-phosphocholine Property

Melting point:
236°C(lit.)
storage temp. 
-20°C
solubility 
slightly sol. in Chloroform
form 
powder to crystal
color 
White to Almost white
biological source
semisynthetic
BRN 
3923978
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
NRJAVPSFFCBXDT-HUESYALOSA-N
SMILES
[C@H](OC(=O)CCCCCCCCCCCCCCCCC)(COP([O-])(=O)OCC[N+](C)(C)C)COC(=O)CCCCCCCCCCCCCCCCC |&1:0,r|
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
10-21
HS Code 
29232000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H336May cause drowsiness or dizziness

H351Suspected of causing cancer

H372Causes damage to organs through prolonged or repeated exposure

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P1138
Product name
1,2-Distearoyl-sn-glycero-3-phosphocholine
Purity
≥99%
Packaging
1g
Price
$532
Updated
2025/07/31
Sigma-Aldrich
Product number
P1138
Product name
1,2-Distearoyl-sn-glycero-3-phosphocholine
Purity
≥99%
Packaging
5g
Price
$2440
Updated
2025/07/31
Sigma-Aldrich
Product number
W2660
Product name
1,2-Distearoyl-sn-glycero-3-phosphocholine
Purity
DSPC, GMP, powder
Packaging
1G
Price
$253
Updated
2022/05/15
Sigma-Aldrich
Product number
W2660
Product name
1,2-Distearoyl-sn-glycero-3-phosphocholine
Purity
DSPC, GMP, powder
Packaging
10G
Price
$956
Updated
2022/05/15
Sigma-Aldrich
Product number
W2660
Product name
1,2-Distearoyl-sn-glycero-3-phosphocholine
Purity
DSPC, GMP, powder
Packaging
100G
Price
$2396
Updated
2022/05/15
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1,2-Distearoyl-sn-glycero-3-phosphocholine Chemical Properties,Usage,Production

Description

1,2-Distearoyl-sn-glycero-3-PC (DSPC) is a phospholipid containing the saturated long-chain (18:0) stearic acid inserted at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.

Chemical Properties

solid

Uses

18:0 PC (DSPC) has been used:

  • in the microbubble monolayer preparation for biomolecule delivery studies into protoplasts
  • in the preparation of liposomes for immobilization studies
  • in the generation of porphyrin-phospholipid (PoP) liposomes for irinotecan (IRT) and doxorubicin delivery

Definition

ChEBI: A phosphatidylcholine 36:0 in which both phosphatidyl acyl groups are specified as stearoyl (octadecanoyl).

General Description

1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) is a phospholtidylcholine with alkyl chain comprising 18 carbons. It has phophatidylcholine head group and its structure is similar to 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC).

Biochem/physiol Actions

1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) is used in combination with other members of phosphatidylcholine for the generation of mixed bilayer system. It is majorly used in conventional and stealth liposome preparation for drug delivery studies.

References

[1] PERNILLE H?YRUP  Kent J  Ole G Mouritsen. Phospholipase A2 activity towards vesicles of DPPC and DMPC–DSPC containing small amounts of SMPC[J]. Biochimica et biophysica acta. Biomembranes, 2001, 1515 2: Pages 133-143. DOI: 10.1016/s0005-2736(01)00407-2
[2] FREDERICK A HEBERLE  Gerald W F. Phase separation in lipid membranes.[J]. Cold Spring Harbor perspectives in biology, 2011, 3 4. DOI: 10.1101/cshperspect.a004630
[3] S MABREY  J M S. Investigation of phase transitions of lipids and lipid mixtures by sensitivity differential scanning calorimetry.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1976, 73 11: 3862-3866. DOI: 10.1073/pnas.73.11.3862

1,2-Distearoyl-sn-glycero-3-phosphocholine Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2-Distearoyl-sn-glycero-3-phosphocholine Suppliers

Suzhou Highfine Biotech Co., Ltd
Tel
0512-69209928 18796809688
Fax
0512-68417696
Email
zhouyingxiang@highfine.com
Country
China
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475
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75
Suzhou Xingbei Pharmaceutical Technology Co., Ltd
Tel
0512-0512-68437753 13861119411
Email
331723639@qq.com
Country
China
ProdList
207
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58
Beijing Minruida Technology Co., Ltd.
Tel
010-82387566 18001021521;
Fax
82387566-801
Email
sales@mreda.com.cn
Country
China
ProdList
10083
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Xiamen Sinopeg Biotech Co., Ltd.
Tel
400-9189898 17359873007
Email
sales@sinopeg.com
Country
China
ProdList
530
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Suzhou Zehou Biotechnology Co. , Ltd.
Tel
0512-68716880 19984816880
Fax
18075373931
Email
sales@growingchem.com
Country
China
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Chongqing Botao Biotechnology Co., LTD
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15223382610
Email
danny@chemdad.com
Country
China
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2032
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Shenyang Gold Jyouki Chemical Industry Co., Ltd
Tel
021-58388811 15840200466
Fax
+86-24-31694249
Email
sunqr@jyouki.com
Country
China
ProdList
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Shanghai Jindi Pharmaceutical Technology Co., Ltd
Tel
13564401937
Email
wangtao@jindipharma.com.cn
Country
China
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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View Lastest Price from 1,2-Distearoyl-sn-glycero-3-phosphocholine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
1,2-Distearoyl-sn-glycero-3-phosphocholine 816-94-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
10000KGS
Release date
2025-05-26
Henan Fengda Chemical Co., Ltd
Product
1,2-Distearoyl-sn-glycero-3-phosphocholine 816-94-4
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-31
Jiangsu Nata Opto-electronic Material Co.,Ltd.
Product
1,2-distearoyl-sn-glycero-3-phosphocholine 816-94-4
Price
US $0.00-0.00/KG
Min. Order
0.1KG
Purity
98%
Supply Ability
250KG
Release date
2023-05-22

816-94-4, 1,2-Distearoyl-sn-glycero-3-phosphocholineRelated Search:


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  • [O-(1-O,2-O-Distearoyl-L-glycero-3-phospho)choline]anion
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  • L-α-Phosphatidylcholine, distearoyl
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  • propyl (2-(trimethylammonio)
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  • 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium,4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxooctadecyl)oxy]-, inner salt,4-oxide, (7R)-
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  • 816-94-4
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