1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Product Name: 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
CAS No.: 63-89-8
Chemical Name: 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Synonyms: DPPC;COLFOSCERIL PALMITATE;1,2-DIHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;16:0 PC;DIPALMITOYL LECITHIN;L-A-LECITHIN DIPALMITOYL;DIPALMITOYL-L-ALPHA-LECITHIN;B,G-DIPALMITOYL-L-A-LECITHIN;L-ALPHA-LECITHIN, DIPALMITOYL;1,2-dipalmitoyl-sn-glycero-3-PC
CBNumber: CB6164209
Molecular Formula: C40H80NO8P
Formula Weight: 734.04
MOL File: 63-89-8.mol

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1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Property

Melting point:: 229-229.5 °C
alpha: D23 +6.6° (c = 4.2 in 1:1 chloroform-methanol)
storage temp.: -20°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White
Merck: 14,2477
Stability:: Stable. Incompatible with strong oxidizing agents.
InChIKey: KILNVBDSWZSGLL-KXQOOQHDSA-N
CAS DataBase Reference: 63-89-8(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
F: 10-21
HS Code: 29232000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H336May cause drowsiness or dizziness

H351Suspected of causing cancer

H372Causes damage to organs through prolonged or repeated exposure

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P0763
Product name: 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
Purity: semisynthetic, ≥99%
Packaging: 1g
Price: $595
Updated: 2024/03/01

Sigma-Aldrich

Product number: P0763
Product name: 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
Purity: semisynthetic, ≥99%
Packaging: 5g
Price: $2520
Updated: 2024/03/01

TCI Chemical

Product number: D3925
Product name: 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
Purity: >98.0%(HPLC)
Packaging: 200mg
Price: $104
Updated: 2024/03/01

TCI Chemical

Product number: D3925
Product name: 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $334
Updated: 2024/03/01

Cayman Chemical

Product number: 10009473
Product name: 1,2-Dipalmitoyl-sn-glycero-3-PC
Purity: ≥98%
Packaging: 25mg
Price: $32
Updated: 2024/03/01

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1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties,Usage,Production

Description

DPPC, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine, is a phospholipid containing the 16 carbon fatty acid/palmitic acid (16:0) at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. Due to the medium size of fatty acid chain, DLPC is used to form thinner membranes or lipid bilayers.

Chemical Properties

white powder

Uses

16:0 PC (DPPC) is suitable for use:

in vesicle preparation
as the main phospholipid component for all ultrasound contrast agents (UCA) formulations
as a component for microbubble preparation
in the preparation of lipid bilayers

Uses

16:0 PC (DPPC) has been used in the generation of thymoquinone (TQ) liposomes, gold nanorods and calcium chloride encapsulated liposomes and bilayers for biophysical studies.

Uses

1,2-dipalmitoyl-sn-glycero-3-phosphocholine is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).

Definition

ChEBI: A phosphatidylcholine 32:0 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl). A synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of pulmonary surfactants.

General Description

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.

Biochem/physiol Actions

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Purification Methods

It has three crystalline forms 1, 2 and ' which change at 60-70o and at 229o, respectively. In order to obtain a fine powder, ~2 g are dissolved in CHCl3 (15mL) and pet ether (b 35-60o) is added; the solution is evaporated to dryness in vacuo at <20o and then dried at 0.1mm over CaCl2. [Baer & Maurukas J Am Chem Soc 74 158 1952, Baer & Kates J Biol Chem 185 615 1950, Beilstein 4 IV 1463.]

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials

Raw materials

TYLOXAPOL

Preparation Products

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1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Suppliers

Americas 1 Belgium 2 Canada 2 China 203 Europe 3 Germany 2 India 7 Italy 1 Japan 6 Sweden 1 Switzerland 8 The Netherlands 1 Ukraine 1 United Kingdom 7 United States 37 Global 282

Suzhou Highfine Biotech Co., Ltd

Tel: 0512-69209928 18306209922
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AVT(Shanghai) Pharmaceutical Tech Co., Ltd.

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Shochem(Shanghai)Co.,Ltd

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Suzhou Zehou Biotechnology Co. , Ltd.

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Suzhou Xingbei Pharmaceutical Technology Co., Ltd

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Tianjin Yixing Biotechnology Co. , Ltd.

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J & K SCIENTIFIC LTD.

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Meryer (Shanghai) Chemical Technology Co., Ltd.

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TCI (Shanghai) Development Co., Ltd.

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View Lastest Price from 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE manufacturers

Dideu Industries Group Limited

Product: 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 63-89-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-28

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 63-89-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 63-89-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

63-89-8, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINERelated Search:

16:0 PC

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE

1,2-DIHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

(R)-2,3-Bis(palMitoyloxy)propyl (2-(triMethylaMMonio)ethyl) phosphate

LIPOID PE 180/180-PEG

L-A-LECITHIN DIPALMITOYL

L-ALPHA-DIPALMITOYL PHOSPHATIDYLCHOLINE

L-ALPHA-LECITHIN, DIPALMITOYL

L-ALPHA-PHOSPHATIDYLCHOLINE, DIPALMITOYL

L-ALPHA-PHOSPHATIDYLCHOLINE, DIPALMITOYL (C16:0)

L-BETA,GAMMA-DIPALMITOYL-ALPHA-LECITHIN

DIPALMITOYL-L-ALPHA-LECITHIN

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine,1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine, L-α-Phosphatidylcholine, dipalmitoyl

1,2-dipalmitoyl-sn-glycero-3-PC

L-alpha-DipalMitoyl phosphatidylcholine, 98% 500MG

(7R)-4-Hydroxy-N,N,N-triMethyl-10-oxo- 7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacosan-1-aMiniuM Inner Salt 4-Oxide

1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine

1,2-Bis(pal

1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine 2,3-Bis(palmitoyloxy)propyl [2-(Trimethylammonio)ethyl]phosphate

L-b,g-DipalMitoyl-a-lecithin, DPPC

DPPC L-1116

(7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]- 3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide, inner salt

1,2-Dihexadecanoyl-sn-glycero-3-phosphorylcholine

1,2-Dipalmitoyl-L-lecithin

L-α-Phosphatidylcholine, dipalmitoyl

L-β,γ-Dipalmi

(7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]- 3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide, inner salt 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine 1,2-Dihexadecanoyl-sn-glycero-3-phosph

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO

L-alpha-Dipalmitoyl lecithin

1,2-dipalmitoyl-sn-glycero-3-phosphocholine(DPPC)

CAS_63-89-8

DIPALMITOYL LECITHIN

DPPC

COLFOSCERIL PALMITATE

B,G-DIPALMITOYL-L-A-LECITHIN

1,2-dipalmitoyl-3-sn-phosphatidylcholine

1,2-dipalmitoyl-L-alpha-phosphatidylcholine

L-A-phosphatidylcholine dipalmitoyl*synthetic

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, SEMISYNTHETIC 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, SEMISYNTHETIC 1

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PH

L-A-DIPALMITOYL LECITHIN

L-a-Lecithin-b,g-dipalmitoyl=DilinoleoylLecithin=Dilinoleoyl-L-a-Lecithin=L-b,g-Dipalmitoyl-a-Lecithin

LecithinL-a-Dipalmitoyl

L-ALFA-PHOSPHATIDYLCHLOLINE, DIPALMITOYL

(R)-(4-oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium 4-oxide

[2-[(R)-2,3-Bis[(1-oxohexadecyl)oxy]propyloxyphosphinatooxy]ethyl]dimethylmethanaminium

L-alpha-Dipalmitoyl phosphatidylcholine,98%

Colfosceril

3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-(1-oxohexadecyl)oxy-, inner salt, 4-oxide, (7R)-

3-sn-phosphatidylcholine, 1,2-dipalmitoyl

2-[[(2R)-2,3-dihexadecanoyloxypropoxy]-oxido-phosphoryl]oxyethyl-trimethyl-azanium

Dipalmitoyl-L-ALPHA-phosphatidyl choline

L-á-Phosphatidylcholine dipalmitoyl

Dipalmitoyl-D62-SN-Glycero-3-Phospho-Choline

1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine, L-α-Phosphatidylcholine, dipalmitoyl

Coifosceril Palmitate