ChemicalBook > CAS DataBase List > 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Product Name
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
CAS No.
63-89-8
Chemical Name
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Synonyms
DPPC;COLFOSCERIL PALMITATE;1,2-DIHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;16:0 PC;DIPALMITOYL LECITHIN;L-A-LECITHIN DIPALMITOYL;DIPALMITOYL-L-ALPHA-LECITHIN;B,G-DIPALMITOYL-L-A-LECITHIN;L-ALPHA-LECITHIN, DIPALMITOYL;1,2-dipalmitoyl-sn-glycero-3-PC
CBNumber
CB6164209
Molecular Formula
C40H80NO8P
Formula Weight
734.04
MOL File
63-89-8.mol
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1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Property

Melting point:
229-229.5 °C
alpha 
D23 +6.6° (c = 4.2 in 1:1 chloroform-methanol)
storage temp. 
-20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
Merck 
14,2477
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
KILNVBDSWZSGLL-KXQOOQHDSA-N
CAS DataBase Reference
63-89-8(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
F 
10-21
HS Code 
29232000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H336May cause drowsiness or dizziness

H351Suspected of causing cancer

H372Causes damage to organs through prolonged or repeated exposure

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P0763
Product name
1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
Purity
semisynthetic, ≥99%
Packaging
1g
Price
$595
Updated
2024/03/01
Sigma-Aldrich
Product number
P0763
Product name
1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
Purity
semisynthetic, ≥99%
Packaging
5g
Price
$2520
Updated
2024/03/01
TCI Chemical
Product number
D3925
Product name
1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
Purity
>98.0%(HPLC)
Packaging
200mg
Price
$104
Updated
2024/03/01
TCI Chemical
Product number
D3925
Product name
1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
Purity
>98.0%(HPLC)
Packaging
1g
Price
$334
Updated
2024/03/01
Cayman Chemical
Product number
10009473
Product name
1,2-Dipalmitoyl-sn-glycero-3-PC
Purity
≥98%
Packaging
25mg
Price
$32
Updated
2024/03/01
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1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties,Usage,Production

Description

DPPC, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine, is a phospholipid containing the 16 carbon fatty acid/palmitic acid (16:0) at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. Due to the medium size of fatty acid chain, DLPC is used to form thinner membranes or lipid bilayers.

Chemical Properties

white powder

Uses

16:0 PC (DPPC) is suitable for use:

  • in vesicle preparation
  • as the main phospholipid component for all ultrasound contrast agents (UCA) formulations
  • as a component for microbubble preparation
  • in the preparation of lipid bilayers

Uses

16:0 PC (DPPC) has been used in the generation of thymoquinone (TQ) liposomes, gold nanorods and calcium chloride encapsulated liposomes and bilayers for biophysical studies.

Uses

1,2-dipalmitoyl-sn-glycero-3-phosphocholine is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).

Definition

ChEBI: A phosphatidylcholine 32:0 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl). A synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of pulmonary surfactants.

General Description

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.

Biochem/physiol Actions

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Purification Methods

It has three crystalline forms 1, 2 and ' which change at 60-70o and at 229o, respectively. In order to obtain a fine powder, ~2 g are dissolved in CHCl3 (15mL) and pet ether (b 35-60o) is added; the solution is evaporated to dryness in vacuo at <20o and then dried at 0.1mm over CaCl2. [Baer & Maurukas J Am Chem Soc 74 158 1952, Baer & Kates J Biol Chem 185 615 1950, Beilstein 4 IV 1463.]

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials

Raw materials

TYLOXAPOL

Preparation Products

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1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Suppliers

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View Lastest Price from 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE manufacturers

Dideu Industries Group Limited
Product
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 63-89-8
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-07-28
Zhuozhou Wenxi import and Export Co., Ltd
Product
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 63-89-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 63-89-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

63-89-8, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINERelated Search:

1,2-DI[PERDEUTERO]HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-Distearoyl-sn-glycero-3-phosphocholine 1,2-DIHEPTADECANOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE 1,2-DIEICOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-STEAROYL-2-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-PALMITOYL-2-STEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DISTEAROYL-D70-3-SN-GLYCEROPHOSPHATIDYLCHOLINE 1,2-DINONADECANOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE Lecithin phosphorylcholine Palmitic acid Choline hydroxide L-ALPHA-LECITHIN 1,2-DIDOCOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DI 3,7,11,15-TETRAMETHYLHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 2,3-DIPALMITOYL-SN-GLYCERO-1-PHOSPHOCHOLINE 1,2-Dipalmitoyl-SN-Glycero-3-Phosphocholine-D9

  • 16:0 PC
  • 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
  • 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE
  • 1,2-DIHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • (R)-2,3-Bis(palMitoyloxy)propyl (2-(triMethylaMMonio)ethyl) phosphate
  • LIPOID PE 180/180-PEG
  • L-A-LECITHIN DIPALMITOYL
  • L-ALPHA-DIPALMITOYL PHOSPHATIDYLCHOLINE
  • L-ALPHA-LECITHIN, DIPALMITOYL
  • L-ALPHA-PHOSPHATIDYLCHOLINE, DIPALMITOYL
  • L-ALPHA-PHOSPHATIDYLCHOLINE, DIPALMITOYL (C16:0)
  • L-BETA,GAMMA-DIPALMITOYL-ALPHA-LECITHIN
  • DIPALMITOYL-L-ALPHA-LECITHIN
  • 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine,1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine, L-α-Phosphatidylcholine, dipalmitoyl
  • 1,2-dipalmitoyl-sn-glycero-3-PC
  • L-alpha-DipalMitoyl phosphatidylcholine, 98% 500MG
  • (7R)-4-Hydroxy-N,N,N-triMethyl-10-oxo- 7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacosan-1-aMiniuM Inner Salt 4-Oxide
  • 1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine
  • 1,2-Bis(pal
  • 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine 2,3-Bis(palmitoyloxy)propyl [2-(Trimethylammonio)ethyl]phosphate
  • L-b,g-DipalMitoyl-a-lecithin, DPPC
  • DPPC L-1116
  • (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]- 3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide, inner salt
  • 1,2-Dihexadecanoyl-sn-glycero-3-phosphorylcholine
  • 1,2-Dipalmitoyl-L-lecithin
  • L-α-Phosphatidylcholine, dipalmitoyl
  • L-β,γ-Dipalmi
  • (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]- 3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide, inner salt 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine 1,2-Dihexadecanoyl-sn-glycero-3-phosph
  • 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO
  • L-alpha-Dipalmitoyl lecithin
  • 1,2-dipalmitoyl-sn-glycero-3-phosphocholine(DPPC)
  • CAS_63-89-8
  • DIPALMITOYL LECITHIN
  • DPPC
  • COLFOSCERIL PALMITATE
  • B,G-DIPALMITOYL-L-A-LECITHIN
  • 1,2-dipalmitoyl-3-sn-phosphatidylcholine
  • 1,2-dipalmitoyl-L-alpha-phosphatidylcholine
  • L-A-phosphatidylcholine dipalmitoyl*synthetic
  • 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, SEMISYNTHETIC 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, SEMISYNTHETIC 1
  • 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PH
  • L-A-DIPALMITOYL LECITHIN
  • L-a-Lecithin-b,g-dipalmitoyl=DilinoleoylLecithin=Dilinoleoyl-L-a-Lecithin=L-b,g-Dipalmitoyl-a-Lecithin
  • LecithinL-a-Dipalmitoyl
  • L-ALFA-PHOSPHATIDYLCHLOLINE, DIPALMITOYL
  • (R)-(4-oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium 4-oxide
  • [2-[(R)-2,3-Bis[(1-oxohexadecyl)oxy]propyloxyphosphinatooxy]ethyl]dimethylmethanaminium
  • L-alpha-Dipalmitoyl phosphatidylcholine,98%
  • Colfosceril
  • 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-(1-oxohexadecyl)oxy-, inner salt, 4-oxide, (7R)-
  • 3-sn-phosphatidylcholine, 1,2-dipalmitoyl
  • 2-[[(2R)-2,3-dihexadecanoyloxypropoxy]-oxido-phosphoryl]oxyethyl-trimethyl-azanium
  • Dipalmitoyl-L-ALPHA-phosphatidyl choline
  • L-á-Phosphatidylcholine dipalmitoyl
  • Dipalmitoyl-D62-SN-Glycero-3-Phospho-Choline
  • 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine, L-α-Phosphatidylcholine, dipalmitoyl
  • Coifosceril Palmitate