6-CHLOROINDOLE-3-CARBOXYLIC ACID

Product Name: 6-CHLOROINDOLE-3-CARBOXYLIC ACID
CAS No.: 766557-02-2
Chemical Name: 6-CHLOROINDOLE-3-CARBOXYLIC ACID
Synonyms: 6-chloro-3-indole acid;6-CHLOROINDOLE-3-CARBOXYLIC ACID;1H-INDOLE-3-CARBOXYLICACID,6-CHLORO
CBNumber: CB2728261
Molecular Formula: C9H6ClNO2
Formula Weight: 195.6
MOL File: 766557-02-2.mol

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6-CHLOROINDOLE-3-CARBOXYLIC ACID Property

Boiling point:: 449.7±25.0 °C(Predicted)
Density: 1.548
storage temp.: 2-8°C
pka: 3.61±0.10(Predicted)
Appearance: Off-white to pink Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C380798
Product name: 6-Chloroindole-3-carboxylicacid
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: C380798
Product name: 6-Chloroindole-3-carboxylicacid
Packaging: 500mg
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: W8341
Product name: 6-Chloroindole-3-carboxylicacid
Packaging: 250mg
Price: $64
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC140682
Product name: 6-Chloro-1H-indole-3-carboxylic acid
Packaging: 1g
Price: $83
Updated: 2021/12/16

Apolloscientific

Product number: OR913258
Product name: 6-Chloroindole-3-carboxylicacid
Purity: 98%
Packaging: 1g
Price: $115
Updated: 2021/12/16

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6-CHLOROINDOLE-3-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

676477-10-4

766557-02-2

General procedure for the synthesis of 6-chloroindole-3-carboxylic acid from 1-(6-chloro-3-indolyl)-2,2,2-trifluoroethanone: b) 21.6 g (87.2 mmol) of 1-(6-chloro-1H-indol-3-yl)-2,2,2-trifluoroethanone was dissolved in 110 mL of aqueous 4 M potassium hydroxide solution and heated to reflux for 2 hours. Upon completion of the reaction, the reaction solution was cooled to 0 °C and neutralized with 36.7 mL of concentrated aqueous hydrochloric acid, at which point a white solid precipitated from the solution. The solid product was collected by filtration and washed with deionized water. Finally, the product was dried under high vacuum at 80 °C to give 16.4 g (96% yield) of 6-chloroindole-3-carboxylic acid as a light yellow solid. Mass spectrometry result: m/e 194 (M-H+, 100%).

References

[1] Patent: US2007/72888, 2007, A1. Location in patent: Page/Page column 14-15
[2] Journal of Medicinal Chemistry, 2015, vol. 58, # 5, p. 2275 - 2289
[3] Patent: JP2017/171619, 2017, A. Location in patent: Paragraph 0133; 0135
[4] Patent: EP2548864, 2013, A1. Location in patent: Paragraph 0175
[5] Patent: WO2013/14102, 2013, A1. Location in patent: Page/Page column 26; 32

6-CHLOROINDOLE-3-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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6-CHLOROINDOLE-3-CARBOXYLIC ACID Suppliers

China 75 Germany 1 India 1 Switzerland 1 United Kingdom 2 United States 11 Global 91

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View Lastest Price from 6-CHLOROINDOLE-3-CARBOXYLIC ACID manufacturers

Career Henan Chemical Co

Product: 6-CHLOROINDOLE-3-CARBOXYLIC ACID 766557-02-2
Price: US $1.00/g
Min. Order: 100g
Purity: 99%
Supply Ability: KG/T
Release date: 2019-12-18

766557-02-2, 6-CHLOROINDOLE-3-CARBOXYLIC ACIDRelated Search:

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6-CHLOROINDOLE-3-CARBOXYLIC ACID

6-chloro-3-indole acid

1H-INDOLE-3-CARBOXYLICACID,6-CHLORO

766557-02-2

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