ChemicalBook > CAS DataBase List > Sennoside B

Sennoside B

Product Name: Sennoside B
CAS No.: 128-57-4
Chemical Name: Sennoside B
Synonyms: Tisasen B;PURSENNIDE;GLYSENNIDE;SENNOSIDE B;SENNOSIDE B(P);Sennoside B RS;SENNIDINE B(RG);SENNOSIDE B(SH);Sennoside B(AS);SENNOSIDE B hplc
CBNumber: CB2728337
Molecular Formula: C42H38O20
Formula Weight: 862.74
MOL File: 128-57-4.mol

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Sennoside B Property

Melting point:: 209～212℃
alpha: D20 -100° (c = 0.2 in 70% acetone); D20 -67° (c = 0.4 in 70% dioxane)
Boiling point:: 698.48°C (rough estimate)
Density: 1.3066 (rough estimate)
refractive index: 1.7630 (estimate)
storage temp.: 2-8°C
solubility: DMSO (Very Slightly, Heated), Methanol (Slightly, Heated)
pka: 3.31±0.40(Predicted)
form: Solid
color: Light Yellow to Dark Yellow
BRN: 5723747
Stability:: Hygroscopic
InChIKey: IPQVTOJGNYVQEO-IDJKMNDUNA-N
LogP: 1.880 (est)
CAS DataBase Reference: 128-57-4(CAS DataBase Reference)

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Safety

Risk Statements: 22
Safety Statements: 22-45-24/25
WGK Germany: 3
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1612029
Product name: Sennoside B
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 20mg
Price: $576
Updated: 2025/07/31

Sigma-Aldrich

Product number: 00530580
Product name: Sennoside B
Purity: primary reference standard
Packaging: 25 mg
Price: $650
Updated: 2025/07/31

Sigma-Aldrich

Product number: 75412
Product name: Sennoside B
Purity: analytical standard
Packaging: 25mg
Price: $241
Updated: 2022/05/15

TCI Chemical

Product number: E1546
Product name: Sennoside B
Packaging: 100MG
Price: $240
Updated: 2025/07/31

Cayman Chemical

Product number: 28410
Product name: Sennoside B
Packaging: 10mg
Price: $63
Updated: 2024/03/01

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Sennoside B Chemical Properties,Usage,Production

Chemical Properties

White to brown powder

Uses

Sennoside B is used in the inhibition of platelet driven growth factor (PDGF) used and may inhibit proliferative disease which depend upon the PDGF pathway. Laxative.

Definition

ChEBI: A member of the class of sennosides that is (9R,9'S)-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid which is substituted by hydroxy groups at positions 4 and 4', by beta-D glucopyranosyloxy groups at positions 5 and 5', and by oxo groups at positions 10 and 10'.

in vivo

Sennoside B (100 mg/kg; p.o.) shows gastroprotective activities by reducing lesion indices in HCl?EtOH and Indomethacin (HY-14397) induces gastritis in rats^[1].

Animal Model:	170-200g, Male Sprague-Dawley rats (HCl?EtOH-induced gastritis)^[1]
Dosage:	100 mg/kg
Administration:	P.o.
Result:	Reduced lesion indices to 60.8 ± 18.4 mm, by inhibition rate of 39.9%.

Purification Methods

Sennoside B forms yellow crystals from aqueous acetone or large volumes of H2O. [Stoll et al. Helv Chim Acta 32 1896 1900, Beilstein 17 III/IV 3402.]

Sennoside B Preparation Products And Raw materials

Raw materials

Preparation Products

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Sennoside B Suppliers

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View Lastest Price from Sennoside B manufacturers

Lianyungang Kaiyu Environmental Tech Co., Ltd.

Product: Sennoside B 128-57-4
Price: US $1200.00-1100.00/ton
Min. Order: 1ton
Purity: 99%
Supply Ability: 1000T/M
Release date: 2025-11-06

Shaanxi Dideu New Materials Co. Ltd

Product: Sennoside B 128-57-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2025-11-06

Changsha Staherb Natural Ingredients Co., Ltd.

Product: Sennoside B; Senna leaf extract 128-57-4
Price: US $0.00/MG
Min. Order: 20MG
Purity: 95%-99% HPLC
Supply Ability: 1000KG
Release date: 2022-09-19

128-57-4, Sennoside BRelated Search:

CHLOROPHOSPHONAZO III Sennoside D SENNOSIDE A(SH),SENNOSIDE A(P),SENNOSIDE,CALCIUM SENNOSIDE 5%, 10%, 20%, 60%,Sennoside A std.,SENNOSIDE A hplc,SENNOSIDE A WITH HPLC,Sennoside A1,SENNOSIDE A Sennoside C SENNIDINE A 4-Acetylbenzoic acid 4-FORMYL-3-HYDROXYBENZOIC ACID 2,2'-DIHYDROXYBENZOPHENONE 3-Hydroxy-4-methylbenzoic acid 5-ISOPROPYL-3-METHYLPHENOL 4-BROMOBENZHYDROL BIANTHRONYL HELICIN 4-ETHYL-3-HYDROXYBENZOIC ACID 1,1,2,2-TETRAPHENYLETHANE SENNOSIDE A AND B,SENNOSIDE SENNOSIDES 2-METHOXY-2'-METHYLBENZOPHENONE

PURSENNIDE

SENNOSIDE B 96.5+%

Sennoside B std.

9,9-Bianthracene-2,2-dicarboxylic acid, 5,5-bis(.beta.-D-glucopyranosyloxy)-9,9,10,10-tetrahydro-4,4-dihydroxy-10,10-dioxo-, (9R,9S)-

(9S)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid

SENNIDINE B(RG)

SENNOSIDE B(P)

SENNOSIDE B(SH)

SENNOSIDE B hplc

SENNOSIDE B WITH HPLC

Sennoside B, 98%, from Folium sennae

[9,9'-Bianthracene]-2,2'-dicarboxylicacid,5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-,(9R,9'S)-

N,N-dimethyl-4-[(E,3Z)-3-(2-nitro-9-fluorenylidene)prop-1-enyl]aniline

(9R,9'S)-5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-9,9'-bianthracene-2,2'-dicarboxylic acid

(9S,9'R)-5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-9,9'-bianthracene-2,2'-dicarboxylic acid

(9S)-9-[(9R)-2-carboxy-4-hydroxy-10-keto-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-keto-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-9H-anthracene-2-carboxylic acid

Sennoside B ,98%

Tisasen B

(9R,9'S)-4,4'-dihydroxy-10,10'-dioxo-5,5'-bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)-9,9',10,10'-tetrahydro-[9,9'-bianthracene]-2,2'-dicarboxylic acid

Sennoside B, froM FoliuM sennae

Sennoside B (20 mg)

GLYSENNIDE

(9S)-9-[(9R)-2-Carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid

SENNOSIDE B

Sennoside B Standard

Sennoside B RS

Sennoside B(AS)

Sennoside B, 10 mM in DMSO

128-57-4

C42H38O20

SA - SM

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The group of Sennosides

Anthraquinones, Hydroquinones and Quinones

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

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