2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid

Product Name: 2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid
CAS No.: 67776-06-1
Chemical Name: 2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid
Synonyms: SNAP;S-NITROSO-N-ACETYL-D,L-PENICILLAMINE;SUP;RIC4;SEC9;SNP25;CMS18;RIC-4;)₃bA416N4.2
CBNumber: CB2736260
Molecular Formula: C7H12N2O4S
Formula Weight: 220.25
MOL File: 67776-06-1.mol

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2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid Property

Melting point:: 150.5°C
Density: 1.4261 (rough estimate)
refractive index: 1.5400 (estimate)
RTECS: YV9383000
storage temp.: -20°C
solubility: H₂O: ≥2 mg/mL
pka: 3.06±0.10(Predicted)
form: powder
color: green
Water Solubility: H2O: ≥2mg/mL
DMSO: ≥20mg/mL, clear (faint green to very dark green)
CAS DataBase Reference: 67776-06-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N3398
Product name: S-Nitroso-N-acetyl-DL-penicillamine
Purity: ≥97%, powder
Packaging: 25mg
Price: $213
Updated: 2025/07/31

Sigma-Aldrich

Product number: N3398
Product name: S-Nitroso-N-acetyl-DL-penicillamine
Purity: ≥97%, powder
Packaging: 50mg
Price: $336
Updated: 2025/07/31

Cayman Chemical

Product number: 82250
Product name: SNAP
Purity: ≥98%
Packaging: 10mg
Price: $39
Updated: 2024/03/01

Cayman Chemical

Product number: 82250
Product name: SNAP
Purity: ≥98%
Packaging: 25mg
Price: $92
Updated: 2024/03/01

Cayman Chemical

Product number: 82250
Product name: SNAP
Purity: ≥98%
Packaging: 50mg
Price: $172
Updated: 2024/03/01

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2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid Chemical Properties,Usage,Production

Description

SNAP is an S-nitrosothiol which serves as a NO donor and a potent vasodilator. Its stability in solution varies from seconds to hours depending on temperature, buffer composition and metal content. At pH 6-8 and 37°C, the half-life of SNAP is approximately six hours in the presence of transition metal ion chelators.

Chemical Properties

2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid is green crystalline solid

Uses

Produced concentration-related relaxations of mouse anococcygeus, in a range similar to that already found for NO and other nitrovasodilators. A potent relaxant of non-vascular smooth muscle. Serves as an NO donor.

Biochem/physiol Actions

NO donor; vasodilator, smooth muscle relaxant, lymphocyte activator. Activates soluble guanylyl cyclase.

in vivo

SNAP (100μM, 300μM) causes small but significant increases of the electrically evoked [³H]-acetylcholine release in guinea-pig tracheal^[4].

References

[1] BEATRICE ROY Marc F A du Moulinet d’Hardemare. New Thionitrites: Synthesis, Stability, and Nitric Oxide Generation[J]. The Journal of Organic Chemistry, 1994, 59 23: 7019-7026. DOI: 10.1021/jo00102a028
[2] R J SINGH. Mechanism of nitric oxide release from S-nitrosothiols.[J]. The Journal of Biological Chemistry, 1996, 271 31: 18596-18603. DOI: 10.1074/jbc.271.31.18596

2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid Suppliers

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View Lastest Price from 2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid manufacturers

Career Henan Chemical Co

Product: 2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid 67776-06-1
Price: US $2.00/KG
Min. Order: 1g
Purity: 98%min
Supply Ability: ask
Release date: 2020-01-14

67776-06-1, 2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acidRelated Search:

NORPSEUDOEPHEDRINE HCL SNAP-N-SHOOT 0.1MG/ML(REAGENT / STANDARD GRADE),NORPSEUDOEPHEDRINE HCL SNAP-N-SHOOT 1.0MG/ML(SECONDARY STANDARD) S-NITROSO-N-ACETYLPENICILLAMINE (SNAP) P OTENT VASODILATOR ROSIN SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD) ANTI-ALPHA/BETA-SNAP TPX SNAP RING VIALS, (11,6 X 32 MM) WITH INTEGRATED 0,2 ML GLASS MICRO-INSERT, 15 MM TIP, PACK á 100 EA TRIBULOSAPONIN B SNAP-N-SHOOT 0.1MG/ML(P) Α/Β-SNAP MONOCLONAL ANTIBODY HYDROXYVALERENIC ACID SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD) 11MM POLYPROPYLENE PRE-CUT SNAP ON CAP SNAP TOGETHER TEST TUBE RACK FOR 13 MM HYPERFORIN SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD) SNAP-ON ALL-PURPOSE LABORATORY TOOL KIT& RED CLOVER SNAP-N-SHOOT KIT (SECONDARY STANDARD) 1.5 ML EVAPOVIAL SNAP CAP COMBO PACK 100/PACK SNAP-SEAL PP SAMPLE CONTAINER 300ML VALERENIC ACID SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD) FORMONONETIN SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD) EPHEDRA EPHEDRINE ALKALOID SNAP-N-SHOOT KIT 12

N-(ACETYLOXY)-3-NITROSOTHIOVALINE

SNAP

(+/-)-S-NITROSO-N-ACETYLPENICILLAMINE

S-NITROSO-N-ACETYL-D,L-PENICILLAMINE

S-Nitroso-N-acetyl-DL-penicillamine,N-Acetyl-3-(nitrosothio)-DL-valine, S-Nitroso-N-acetylpenicillamine, SNAP

(R)-2-acetaMido-3-Methyl-3-(nitrosothio)butanoic acid

SNAP [S-Nitroso-N-acetylpenicillaMine]

Anti-SNAP25, C-Terminal antibody produced in rabbit

SNP25

SUP

Super protein

Valine,N-acetyl-3-(nitrosothio)-

N-Acetyl-S-nitrosopenicillamine

N-Acetyl-3-(nitrosothio)-DL-valine, S-Nitroso-N-acetylpenicillamine, SNAP

S-Nitroso-N-acetyl-DL-penicillamine,98%

N-Acetyl-3-(nitrosothio)-DL-valine

2-acetamido-3-methyl-3-(nitrosothio)butanoic acid

2-acetamido-3-methyl-3-(nitrososulfanyl)butaic acid

2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid USP/EP/BP

(2R)-2-(acetylamino)-3-methyl-3-(nitrososulfanyl)butanoate

SNitrosoNacetylDLpenicillamine,S Nitroso N acetyl DL penicillamine,Nitric oxide synthases,NOS,inhibit,NO Synthase,Inhibitor

(24 elements in dilute nitric acid) 100 mg/l: Al, B, Ba, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Ga, K, Li, Mg, Mn, Na, Ni, Pb, Se, Sr, Te, Tl, Zn Certipur&#174

(23 elements in diluted nitric acid) 1000 mg/l: Ag, Al, B, Ba, Bi, Ca, Cd, Co, Cr, Cu, Fe, Ga, In, K, Li, Mg, Mn, Na, Ni, Pb, Sr, Tl, Zn Certipur&#174

in HCl 7% 1000 mg/l Pt Certipur&#174

PtCl&#8326

traceable to SRM from NIST H&#8322

)&#8323

2-3% 1000 mg/l Rh Certipur&#174

in HNO&#8323

traceable to SRM from NIST Rh(NO&#8323

Karl Fischer reagent for coulometric water determination for cells with and without diaphragm Aquastar&#174

SNAP, NO donor

bA416N4.2

CMS18

dJ1068F16.2

RIC4

RIC-4

SEC9

67776-06-1

C7H12N2O4S

Signalling