SNAP
- Product Name
- SNAP
- CAS No.
- 79032-48-7
- Chemical Name
- SNAP
- Synonyms
- SNAP;SNAP(D);S-Nitroso-acetyl penicillamine;S-NITROSO-N-ACETYLPENICILLAMINE;N-ACETYL-3-(NITROSOTHIO)-D-VALINE;N-Acetyl-S-nitroso-D-penicillaMine;S-NITRO-N-ACETYL-D,L-PENACILLAMINE;S-nitroso-N-acetyl-D-penicillamine;D-Valine, N-acetyl-3-(nitrosothio)-;S-Nitroso-N-acetyl-D-b,b-dimethylcysteine
- CBNumber
- CB5736261
- Molecular Formula
- C7H12N2O4S
- Formula Weight
- 220.25
- MOL File
- 79032-48-7.mol
SNAP Property
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- H2O: ≥2 mg/mL
- form
- powder
- pka
- 3.06±0.10(Predicted)
- color
- green
N-Bromosuccinimide Price
- Product number
- N522050
- Product name
- S-Nitroso-N-acetyl-D-β,β-dimethylcysteine
- Packaging
- 10mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- AAA0006365
- Product name
- N-ACETYL-3-(NITROSOTHIO)-D-VALINE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $142.8
- Updated
- 2021/12/16
- Product number
- B6368
- Product name
- SNAP
- Packaging
- 50mg
- Price
- $471
- Updated
- 2021/12/16
- Product number
- B6368
- Product name
- SNAP
- Packaging
- 10mg
- Price
- $108
- Updated
- 2021/12/16
SNAP Chemical Properties,Usage,Production
Chemical Properties
Green Crystalline Solid
Uses
The D-isomer of SNAP. Serves as an NO donor.
Definition
ChEBI: A nitroso compound that is N-acetyl-D-penicillamine in which the sulfanyl hydrogen is replaced by a nitroso group.
General Description
Nitric oxide donor that begins to evolve nitric oxide immediately upon solubilization in aqueous buffers (t1/2 = 10 h). Mimics the actions of nitric oxide, including the relaxation of isolated bovine coronary artery rings (EC50 = 130 nM). Markedly activates soluble guanylate cyclase. Also reported to cause the reversible inactivation of protein kinase C activity. Induces apoptosis in mouse thymocytes. Note: 1 set = 4 x 5 mg.
Biological Activity
A stable analog of endogenous S-nitroso compounds. A source of NO in vivo which unlike organic O-nitrates does not induce tolerance. Decomposes slowly in solution with a t ?of 37h.
Biochem/physiol Actions
EC50 = 130 nM in relaxation of isolated bovine coronary artery rings
storage
Store at -20°C
SNAP Preparation Products And Raw materials
Raw materials
Preparation Products
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