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SNAP

Product Name
SNAP
CAS No.
79032-48-7
Chemical Name
SNAP
Synonyms
SNAP;SNAP(D);S-Nitroso-acetyl penicillamine;S-NITROSO-N-ACETYLPENICILLAMINE;N-ACETYL-3-(NITROSOTHIO)-D-VALINE;N-Acetyl-S-nitroso-D-penicillaMine;S-NITRO-N-ACETYL-D,L-PENACILLAMINE;S-nitroso-N-acetyl-D-penicillamine;D-Valine, N-acetyl-3-(nitrosothio)-;S-Nitroso-N-acetyl-D-b,b-dimethylcysteine
CBNumber
CB5736261
Molecular Formula
C7H12N2O4S
Formula Weight
220.25
MOL File
79032-48-7.mol
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SNAP Property

Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: ≥2 mg/mL
form 
powder
pka
3.06±0.10(Predicted)
color 
green
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
N522050
Product name
S-Nitroso-N-acetyl-D-β,β-dimethylcysteine
Packaging
10mg
Price
$130
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0006365
Product name
N-ACETYL-3-(NITROSOTHIO)-D-VALINE
Purity
95.00%
Packaging
10MG
Price
$142.8
Updated
2021/12/16
ApexBio Technology
Product number
B6368
Product name
SNAP
Packaging
50mg
Price
$471
Updated
2021/12/16
ApexBio Technology
Product number
B6368
Product name
SNAP
Packaging
10mg
Price
$108
Updated
2021/12/16
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SNAP Chemical Properties,Usage,Production

Chemical Properties

Green Crystalline Solid

Uses

The D-isomer of SNAP. Serves as an NO donor.

Definition

ChEBI: A nitroso compound that is N-acetyl-D-penicillamine in which the sulfanyl hydrogen is replaced by a nitroso group.

General Description

Nitric oxide donor that begins to evolve nitric oxide immediately upon solubilization in aqueous buffers (t1/2 = 10 h). Mimics the actions of nitric oxide, including the relaxation of isolated bovine coronary artery rings (EC50 = 130 nM). Markedly activates soluble guanylate cyclase. Also reported to cause the reversible inactivation of protein kinase C activity. Induces apoptosis in mouse thymocytes. Note: 1 set = 4 x 5 mg.

Biological Activity

A stable analog of endogenous S-nitroso compounds. A source of NO in vivo which unlike organic O-nitrates does not induce tolerance. Decomposes slowly in solution with a t ?of 37h.

Biochem/physiol Actions

EC50 = 130 nM in relaxation of isolated bovine coronary artery rings

storage

Store at -20°C

SNAP Preparation Products And Raw materials

Raw materials

Preparation Products

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SNAP Suppliers

Canada 1 China 14 Germany 2 India 1 Japan 2 Switzerland 1 United Kingdom 4 United States 9 Global 34
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91

79032-48-7, SNAPRelated Search:

2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid SNAP SNAP

  • S-Nitroso-acetyl penicillamine
  • 2-acetamido-3-methyl-3-(nitrosothio)butyric acid
  • 2-acetamido-3-methyl-3-nitrososulfanylbutanoic acid
  • 2-acetamido-3-methyl-3-nitrososulfanyl-butanoic acid
  • N-Acetyl-S-nitroso-D-penicillaMine
  • N-ACETYL-3-(NITROSOTHIO)-D-VALINE
  • SNAP
  • SNAP(D)
  • S-NITRO-N-ACETYL-D,L-PENACILLAMINE
  • S-NITROSO-N-ACETYL-D-BETA,BETA-DIMETHYLCYSTEINE
  • S-NITROSO-N-ACETYLPENICILLAMINE
  • S-NITROSO-N-ACETYLPENICILLAMINE (SNAP) P OTENT VASODILATOR
  • S-Nitroso-N-acetyl-D-b,b-dimethylcysteine
  • S-nitroso-N-acetyl-D-penicillamine
  • S-Nitroso-N-acetyl-D-β,β-dimethylcysteine
  • D-Valine, N-acetyl-3-(nitrosothio)-
  • 79032-48-7
  • Nitric Oxide Metabolism
  • Enzymes, Inhibitors, and Substrates
  • BioChemical
  • Biochemicals and Reagents
  • Cell Signaling Enzymes
  • Application Index
  • NO Donors
  • Nitric Oxide Reagents
  • Nitric Oxide