Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate

Product Name: Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate
CAS No.: 94790-35-9
Chemical Name: Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate
Synonyms: TCFH;TetraMethylchloroforMaMidiniuM Hexafluorophosphate;N,N,N',N'-TETRAMETHYLCHLOROFORMAMIDINIUM HEXAFLUOROPHOSPHATE;tetramethyluronium hexafluorophosphate;TCFH N,N,N,N-TETRAMETHYLCHLOROFORMAMIDINIUM-HEXAFLUOROPHOSPHATE;Methanaminium, N-[chloro(dimethylamino)methylene]-N-methyl-, hexafluorophosphate(1-) (1:1);[chloro(dimethylamino)methylidene]-dimethylazanium;N,N,N',N'-Tetramethylchloroformamidinium-hexafluor;-Tetramethylchloroformamidinium hexafluorophosphate;N-[Chloro(dimethylamino)methylene]-N-methyl-methanaminium
CBNumber: CB2748999
Molecular Formula: C5H12ClF6N2P
Formula Weight: 280.58
MOL File: 94790-35-9.mol

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Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate Property

Melting point:: 99-104 °C
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: Soluble in water or 1% acetic acid
form: powder to crystal
color: White to Almost white
Major Application: peptide synthesis
InChI: InChI=1S/C5H12ClN2.F6P/c1-7(2)5(6)8(3)4;1-7(2,3,4,5)6/h1-4H3;/q+1;-1
InChIKey: CUKNPSDEURGZCO-UHFFFAOYSA-N
SMILES: [P+5]([F-])([F-])([F-])([F-])([F-])[F-].C(/Cl)(=[N+](\C)/C)\N(C)C
CAS DataBase Reference: 94790-35-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-40
Safety Statements: 26-36-22
WGK Germany: 3
F: 3-10-21
HS Code: 2931599090
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 09658
Product name: Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate
Purity: ≥98.0% (T)
Packaging: 5 g
Price: $157
Updated: 2026/03/19

TCI Chemical

Product number: C1957
Product name: Chloro-N,N,N',N'-tetramethylformamidinium Hexafluorophosphate
Purity: >98.0%(N)
Packaging: 1g
Price: $17
Updated: 2026/03/19

TCI Chemical

Product number: C1957
Product name: Chloro-N,N,N',N'-tetramethylformamidinium Hexafluorophosphate
Packaging: 25G
Price: $125
Updated: 2026/03/19

TCI Chemical

Product number: C1957
Product name: Chloro-N,N,N',N'-tetramethylformamidinium Hexafluorophosphate
Purity: >98.0%(N)
Packaging: 5g
Price: $42
Updated: 2026/03/19

TRC

Product number: C400030
Product name: Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate
Packaging: 25g
Price: $525
Updated: 2021/12/16

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Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Coupling reagent for peptide synthesis and starting material for preparing other coupling reagents.

reaction suitability

reaction type: Coupling Reactions

Synthesis

After a 2-minute time period, a small portion of oxalyl chloride (2.0 mL, 23 ) was added to a solution of 1,1,3,3-tetramethyl urea (2.5 mL, 21 mmol)/10 mL toluene (2.0 mL, 23 mmol) to the oxalyl chloride (2.0 mL, 23 mmol) solution in 10 mL of toluene. After stirring for 18 hours at room temperature, the reaction mixture was concentrated under reduced pressure to a volume of about 5 mmol. mL volume and the resulting precipitate was collected by filtration. The collected solid was dissolved in about 20 mL of water, followed by treatment with potassium hexafluorophosphate (3.8 g, 21 mmol)/50 mL of aqueous solution while the mixture was vigorously stirred at room temperature to obtain a white precipitate. The precipitate was collected by filtration and dried under vacuum. The solid was subsequently treated with about 8 mL acetone and filtered to remove insoluble material. The resulting filtrate was added in small portions to 60 mL of ether while stirring vigorously at room temperature. The desired product was collected by filtration and dried under vacuum to give 4.5 g (76 %) white solid.

Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate Preparation Products And Raw materials

Raw materials

Preparation Products

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Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate Suppliers

Americas 1 Canada 1 China 173 Europe 2 Germany 2 India 5 Israel 1 Japan 1 Switzerland 1 United Kingdom 3 United States 10 Global 200

Suzhou Highfine Biotech Co., Ltd

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Shaoxing Jiufu New Material Technology Co., LTD

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Binhai gill polypeptide co. LTD

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Xinghua Advanced Materials (Suzhou) Co., Ltd.

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J & K SCIENTIFIC LTD.

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Meryer (Shanghai) Chemical Technology Co., Ltd.

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TCI (Shanghai) Development Co., Ltd.

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ShangHai DEMO Chemical Co.,Ltd

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Beijing HwrkChemical Technology Co., Ltd

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Energy Chemical

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Fax: 021-58436166
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ProdList: 44802
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View Lastest Price from Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate 94790-35-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-11-22

Henan Aochuang Chemical Co.,Ltd.

Product: N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate 94790-35-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-12

Zhuozhou Wenxi import and Export Co., Ltd

Product: N,N,N",N"-Tetramethylchloroformamidinium hexafluorophosphate 94790-35-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

94790-35-9, Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphateRelated Search:

4,4'-Diphenylmethane diisocyanate 1,3-DI-BOC-2-METHYLISOTHIOUREA N-Boc-cadaverine N,N'-Disuccinimidyl carbonate N-Methyldiethanolamine Lithium hexafluorophosphate Methylparaben Hexafluorophosphoric acid Potassium hexafluorophosphate Methanol Sodium hexafluorophosphate Methyl acrylate Methylene Blue Acetonitrile Methyl CHLORO-N,N,N',N'-TETRAMETHYLFORMAMIDINIUM HEXAFLUOROPHOSPHATE Difluorochloromethane Hexafluorophosphate

TCFH N,N,N,N-TETRAMETHYLCHLOROFORMAMIDINIUM-HEXAFLUOROPHOSPHATE

N,N,N'',N''-TETRAMETHYLCHLOROFORMAMIDINIUM HEXAFLUOROPHOSPHATE (TCFH)

tetramethyluronium hexafluorophosphate

N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate (TC

N-[Chloro(dimethylamino)methylene]-N-methyl-methanaminium

N,N,N',N'-Tetramethylchloroformamidinium-hexafluor

N-[Chloro(diMethylaMino)Methylene]-N-Methyl-MethanaMiniuM Hexafluorophosphate

N-[Chloro(dimethylamino)methylene]-N-methyl-methanaminium hexafluorophosphate (1:1)

Chloro-N,N,N',N'-Tetramethylformamidiniumhexafluorophosphate,98%

[chloro(dimethylamino)methylidene]-dimethylazanium

Chloro-N,N,N',N'-tetramethylformamidinium Hexafluorophosphate &gt

Methanaminium, N-[chloro(dimethylamino)methylene]-N-methyl-, hexafluorophosphate(1-) (1:1)

CFH N,N,N‘,N‘-Tetramethylchloroformamidinium-hexafluorophosphe

N. N, N ', N' - Tetramethylchloromethamidine hexafluorophosphate

chloro(dimethylamino)methylene]-dimethyl-ammonium hexafluorophosphate

N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosph

CHLORO-N,N,N',N'-TETRAMETHYLFORMAMIDINIUM HEXAFLUOROPHOSPHATE

Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate

-Tetramethylchloroformamidinium hexafluorophosphate

N,N,N',N'-TETRAMETHYLCHLOROFORMAMIDINIUM HEXAFLUOROPHOSPHATE

TCFH

TetraMethylchloroforMaMidiniuM Hexafluorophosphate

94790-35-9

C5H12ClN2PF6

C5H12ClF6N2P

Condensation & Active Esterification

Coupling

Synthetic Reagents

Phosphonium/Uronium/Formamidinium

Condensation & Active Esterification

Synthetic Organic Chemistry

Aliphatics

Amines