ChemicalBook > CAS DataBase List > N,N'-Disuccinimidyl carbonate

N,N'-Disuccinimidyl carbonate

Product Name
N,N'-Disuccinimidyl carbonate
CAS No.
74124-79-1
Chemical Name
N,N'-Disuccinimidyl carbonate
Synonyms
DSC;Bis(2,5-dioxopyrrolidin-1-yl) carbonate;DISUCCINIMIDYL CARBONATE;SU2O;DI(SUCCINIMIDO) CARBONATE;DI(N-SUCCINIMIDYL) CARBONATE;BIS(N-SUCCINIMIDYL) CARBONATE;Carbonic acid bis-(2,5-dioxo-pyrrolidin-1-yl) ester;(SUO)2CO;DSCsee24500
CBNumber
CB3323388
Molecular Formula
C9H8N2O7
Formula Weight
256.17
MOL File
74124-79-1.mol
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N,N'-Disuccinimidyl carbonate Property

Melting point:
190 °C (dec.)(lit.)
Boiling point:
399.41°C (rough estimate)
Density 
1.5670 (rough estimate)
refractive index 
1.5600 (estimate)
storage temp. 
-20°C
solubility 
Dichloromethane (Slightly, Heated), DMSO
form 
Crystalline Powder
color 
White to slightly yellow
Water Solubility 
Soluble in dimethyl sulfoxide, hot pyridine, acetonitrile and most organic solvents. Insoluble in water.
BRN 
1499137
Stability:
Moisture Sensitive
InChIKey
PFYXSUNOLOJMDX-UHFFFAOYSA-N
CAS DataBase Reference
74124-79-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
3
F 
10-21
TSCA 
No
HS Code 
29299000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.51005
Product name
DSC
Purity
N,N′-Disuccinimidyl carbonate Novabiochem?
Packaging
25g
Price
$222
Updated
2024/03/01
Sigma-Aldrich
Product number
8.51005
Product name
DSC
Purity
N,N′-Disuccinimidyl carbonate Novabiochem?
Packaging
100g
Price
$660
Updated
2024/03/01
Sigma-Aldrich
Product number
8.14971
Product name
Di-(N,N′-succinimidyl) carbonate
Purity
for synthesis
Packaging
5G
Price
$172
Updated
2024/03/01
Sigma-Aldrich
Product number
225827
Product name
N,N′-Disuccinimidyl carbonate
Purity
≥95%
Packaging
1g
Price
$25.74
Updated
2024/03/01
Sigma-Aldrich
Product number
225827
Product name
N,N′-Disuccinimidyl carbonate
Purity
≥95%
Packaging
5g
Price
$111
Updated
2024/03/01
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N,N'-Disuccinimidyl carbonate Chemical Properties,Usage,Production

Chemical Properties

N,N'-Disuccinimidyl carbonate is white to slightly yellow crystalline powder

Uses

N,N'-Disuccinimidyl carbonate is a convenient reagent for the synthesis of N-succinimidyl esters of N-protected amino acids.

Uses

N,N’Disuccinimidyl Carbonate is a commonly used reagent for the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate, synthesis of urea, carbamates and coupling of lig ands to proteins. The coupling reagent property of N,N’Disuucinimidyl Carbonate speeds up coupling process, while reduces the loss of chiral integrity.

Uses

N,N'-Disuccinimidyl carbonate is used to prepare cleavable linker succinimide vinylsufonylethyl carbonate for thiol modified-DNA. It serves as a reagent for the synthesis of carbamates. Further, it is used as a coupling reagent as well as in the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate and coupling of ligand to proteins.

Synthesis Reference(s)

Tetrahedron Letters, 20, p. 4745, 1979 DOI: 10.1016/S0040-4039(01)86699-5

General Description

N,N′-Disuccinimidyl carbonate is used for the HPLC determination of amino compounds.

N,N'-Disuccinimidyl carbonate Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N'-Disuccinimidyl carbonate Suppliers

Americas 1 Belgium 2 Canada 1 China 419 Europe 3 France 1 Germany 12 Hungary 1 India 22 Japan 9 Russia 1 Slovakia 1 South Korea 1 Switzerland 3 United Kingdom 20 United States 55 Global 552
Suzhou Highfine Biotech Co., Ltd
Tel
0512-68311833 13962195826
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0512-68417696
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wuhao@highfine.com
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China
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GenChem & GenPharm (Changzhou) Co., Ltd.
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0519-85720003 18861157602
Fax
0519-85720007
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sales03@genchem.cn
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China
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
Fax
86-10-82849933
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jkinfo@jkchemical.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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INTATRADE GmbH
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+49 3493/605464
Fax
+49 3493/605470
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sales@intatrade.de
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Germany
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future industrial shanghai co., ltd
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400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
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China
ProdList
1995
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Alfa Aesar
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400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
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China
ProdList
30123
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TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
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View Lastest Price from N,N'-Disuccinimidyl carbonate manufacturers

Baoji Guokang Bio-Technology Co., Ltd.
Product
N,N'-Disuccinimidyl carbonate 74124-79-1
Price
US $115.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1-10mt
Release date
2021-06-03
Hebei Weibang Biotechnology Co., Ltd
Product
N,N'-Disuccinimidyl carbonate 74124-79-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2021-10-20
Hebei Mojin Biotechnology Co., Ltd
Product
N,N'-Disuccinimidyl carbonate 74124-79-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-22

74124-79-1, N,N'-Disuccinimidyl carbonateRelated Search:

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  • 2,5-PYRROLIDINEDIONE, 1,1'-[CARBONYLBIS(OXY)]BIS-
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  • N,Nzzhlxy-Disuccinimidyl carbonate (DSC)
  • Carbonic acid, bis(2,5-dioxo-1-pyrrolidinyl) ester
  • N-Succinimidyl Carbonate N,N'-Disuccinimidyl Carbonate DSC
  • DI-(N,N'-SUCCINIMIDYL) CARBONATE FOR SYN
  • N,N-DisucciniMdyl carbonate
  • Bis(2,5-dioxopyrrolidin-1-yl) carbonate 98%
  • N,N'-Disuccinimidyl carbonate, DSC, 1,1'-[Carbonylbis(oxy)]dipyrrolidine-2,5-dione
  • N,N'-DisucciniMidyl carbonate >=95%
  • N,N'-DisucciniMidyl carbonate puruM, >=95.0% (NMR)
  • <i>N</i>,<i>N</i>′-Disuccinimidyl carbonate
  • N,N'-DISUCCINIMIDYL CARBONATE, TECH.
  • DSC [N,N'-DISUCCINIMIDYL CARBONATE]
  • N,N'-Disuccinimidyl carbonate (DSC)
  • N,N'-DisuccinimidylCarbonate98%
  • N,N'-Disuccinimido Carbonate
  • DSCsee24500
  • N,N'-Disuccinimidyl
  • N,N'-Disuccinimidyl carbonate, tech. 85%, remainder N-hydroxysuccinimide
  • N-Succinimidyl carbonate, Di(N-succinimidyl) carbonate, DSC
  • Bis(2,5-dioxopyrrolidin-1-yl) carbonate
  • N,N'-Disuccinimidyl carbonate ,99%
  • 1,1'-(Carbonylbisoxy)bis(pyrrolidine-2,5-dione)
  • 1,1'-[Carbonylbis(oxy)]bis(2,5-pyrrolidinedione)
  • Carbonic acid bis(succinimidyl) ester
  • N,N'-(Carbonylbisoxy)bissuccinimide
  • DSC (Di(N-succinimidyl)carbonate
  • 1,1''-[CARBONYLBIS(OXY)]DIPYRROLIDINE-2,5-DIONE
  • Disuccinimidyl carbonate, Su2O
  • DSC (Di(N-succinimidyl)carbonate: N-Succinimidyl carbonate)
  • N,N'-Disuccinimidyl carbonate≥ 99% (HPLC)
  • DSC N,N'-Disuccinimidyl carbonate Novabiochem
  • Di-(N,N'-succinimidyl) carbonate for synthesis
  • TIMTEC-BB SBB005976
  • SU2O
  • (SUO)2CO
  • BIS(N-SUCCINIMIDYL) CARBONATE
  • DSC
  • DI(SUCCINIMIDO) CARBONATE
  • DISUCCINIMIDYL CARBONATE
  • DI-(N,N'-SUCCINIMIDYL) CARBONATE
  • DI(N-SUCCINIMIDYL) CARBONATE
  • LABOTEST-BB LT00847311
  • N-SUCCINIMIDYL CARBONATE
  • N,N'-DISUCCINIMIDYL CARBONATE
  • N'-Disuccinimidyl carbonate
  • Di(N-succinimidyl)Carbonate&gt
  • N,N''-Disuccinimidyl carbonate, Tech Grade
  • N,N'-Disuccinimidyl carbonate USP/EP/BP
  • N,N′-Disuccinimidyl Carbonate (Technical Grade)
  • Di-(N-Succinimidyl) Carbonate extrapure, 95%
  • N. N '- Disuccinimide carbonate
  • N,N' -dissuccinimide carbonate
  • N,N'-Disuccinimidyl carbonate
  • DSCN,N'-Disuccinimidyl carbonate
  • 74124-79-1