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N,N'-Disuccinimidyl carbonate

Product Name
N,N'-Disuccinimidyl carbonate
CAS No.
74124-79-1
Chemical Name
N,N'-Disuccinimidyl carbonate
Synonyms
DSC;Bis(2,5-dioxopyrrolidin-1-yl) carbonate;DISUCCINIMIDYL CARBONATE;SU2O;DI(SUCCINIMIDO) CARBONATE;DI(N-SUCCINIMIDYL) CARBONATE;BIS(N-SUCCINIMIDYL) CARBONATE;Carbonic acid bis-(2,5-dioxo-pyrrolidin-1-yl) ester;(SUO)2CO;DSCsee24500
CBNumber
CB3323388
Molecular Formula
C9H8N2O7
Formula Weight
256.17
MOL File
74124-79-1.mol
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N,N'-Disuccinimidyl carbonate Property

Melting point:
190 °C (dec.)(lit.)
Boiling point:
399.41°C (rough estimate)
Density 
1.5670 (rough estimate)
refractive index 
1.5600 (estimate)
storage temp. 
-20°C
solubility 
Dichloromethane (Slightly, Heated), DMSO
form 
Crystalline Powder
color 
White to slightly yellow
Water Solubility 
Soluble in dimethyl sulfoxide, hot pyridine, acetonitrile and most organic solvents. Insoluble in water.
BRN 
1499137
Stability:
Moisture Sensitive
InChIKey
PFYXSUNOLOJMDX-UHFFFAOYSA-N
CAS DataBase Reference
74124-79-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
3
F 
10-21
TSCA 
No
HS Code 
29299000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.51005
Product name
DSC
Purity
N,N′-Disuccinimidyl carbonate Novabiochem?
Packaging
25g
Price
$222
Updated
2024/03/01
Sigma-Aldrich
Product number
8.51005
Product name
DSC
Purity
N,N′-Disuccinimidyl carbonate Novabiochem?
Packaging
100g
Price
$660
Updated
2024/03/01
Sigma-Aldrich
Product number
8.14971
Product name
Di-(N,N′-succinimidyl) carbonate
Purity
for synthesis
Packaging
5G
Price
$172
Updated
2024/03/01
Sigma-Aldrich
Product number
225827
Product name
N,N′-Disuccinimidyl carbonate
Purity
≥95%
Packaging
1g
Price
$25.74
Updated
2024/03/01
Sigma-Aldrich
Product number
225827
Product name
N,N′-Disuccinimidyl carbonate
Purity
≥95%
Packaging
5g
Price
$111
Updated
2024/03/01
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N,N'-Disuccinimidyl carbonate Chemical Properties,Usage,Production

Chemical Properties

N,N'-Disuccinimidyl carbonate is white to slightly yellow crystalline powder

Uses

N,N'-Disuccinimidyl carbonate is a convenient reagent for the synthesis of N-succinimidyl esters of N-protected amino acids.

Uses

N,N’Disuccinimidyl Carbonate is a commonly used reagent for the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate, synthesis of urea, carbamates and coupling of lig ands to proteins. The coupling reagent property of N,N’Disuucinimidyl Carbonate speeds up coupling process, while reduces the loss of chiral integrity.

Uses

N,N'-Disuccinimidyl carbonate is used to prepare cleavable linker succinimide vinylsufonylethyl carbonate for thiol modified-DNA. It serves as a reagent for the synthesis of carbamates. Further, it is used as a coupling reagent as well as in the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate and coupling of ligand to proteins.

Synthesis Reference(s)

Tetrahedron Letters, 20, p. 4745, 1979 DOI: 10.1016/S0040-4039(01)86699-5

General Description

N,N′-Disuccinimidyl carbonate is used for the HPLC determination of amino compounds.

N,N'-Disuccinimidyl carbonate Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N'-Disuccinimidyl carbonate Suppliers

Americas 1 Belgium 2 Canada 1 China 419 Europe 3 France 1 Germany 12 Hungary 1 India 22 Japan 9 Russia 1 Slovakia 1 South Korea 1 Switzerland 3 United Kingdom 20 United States 55 Global 552
Nika Company LLC
Tel
--
Fax
--
Email
info@nika-pharm.ru
Country
Russia
ProdList
60
Advantage
58
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View Lastest Price from N,N'-Disuccinimidyl carbonate manufacturers

Baoji Guokang Bio-Technology Co., Ltd.
Product
N,N'-Disuccinimidyl carbonate 74124-79-1
Price
US $115.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1-10mt
Release date
2021-06-03
Hebei Weibang Biotechnology Co., Ltd
Product
N,N'-Disuccinimidyl carbonate 74124-79-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2021-10-20
Hebei Mojin Biotechnology Co., Ltd
Product
N,N'-Disuccinimidyl carbonate 74124-79-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-22

74124-79-1, N,N'-Disuccinimidyl carbonateRelated Search:

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  • 2,5-PYRROLIDINEDIONE, 1,1'-[CARBONYLBIS(OXY)]BIS-
  • di-N,N'-succnimidly carbonat
  • Carbonic acid bis-(2,5-dioxo-pyrrolidin-1-yl) ester
  • N,Nzzhlxy-Disuccinimidyl carbonate (DSC)
  • Carbonic acid, bis(2,5-dioxo-1-pyrrolidinyl) ester
  • N-Succinimidyl Carbonate N,N'-Disuccinimidyl Carbonate DSC
  • DI-(N,N'-SUCCINIMIDYL) CARBONATE FOR SYN
  • N,N-DisucciniMdyl carbonate
  • Bis(2,5-dioxopyrrolidin-1-yl) carbonate 98%
  • N,N'-Disuccinimidyl carbonate, DSC, 1,1'-[Carbonylbis(oxy)]dipyrrolidine-2,5-dione
  • N,N'-DisucciniMidyl carbonate >=95%
  • N,N'-DisucciniMidyl carbonate puruM, >=95.0% (NMR)
  • <i>N</i>,<i>N</i>′-Disuccinimidyl carbonate
  • N,N'-DISUCCINIMIDYL CARBONATE, TECH.
  • DSC [N,N'-DISUCCINIMIDYL CARBONATE]
  • N,N'-Disuccinimidyl carbonate (DSC)
  • N,N'-DisuccinimidylCarbonate98%
  • N,N'-Disuccinimido Carbonate
  • DSCsee24500
  • N,N'-Disuccinimidyl
  • N,N'-Disuccinimidyl carbonate, tech. 85%, remainder N-hydroxysuccinimide
  • N-Succinimidyl carbonate, Di(N-succinimidyl) carbonate, DSC
  • Bis(2,5-dioxopyrrolidin-1-yl) carbonate
  • N,N'-Disuccinimidyl carbonate ,99%
  • 1,1'-(Carbonylbisoxy)bis(pyrrolidine-2,5-dione)
  • 1,1'-[Carbonylbis(oxy)]bis(2,5-pyrrolidinedione)
  • Carbonic acid bis(succinimidyl) ester
  • N,N'-(Carbonylbisoxy)bissuccinimide
  • DSC (Di(N-succinimidyl)carbonate
  • 1,1''-[CARBONYLBIS(OXY)]DIPYRROLIDINE-2,5-DIONE
  • Disuccinimidyl carbonate, Su2O
  • DSC (Di(N-succinimidyl)carbonate: N-Succinimidyl carbonate)
  • N,N'-Disuccinimidyl carbonate≥ 99% (HPLC)
  • DSC N,N'-Disuccinimidyl carbonate Novabiochem
  • Di-(N,N'-succinimidyl) carbonate for synthesis
  • TIMTEC-BB SBB005976
  • SU2O
  • (SUO)2CO
  • BIS(N-SUCCINIMIDYL) CARBONATE
  • DSC
  • DI(SUCCINIMIDO) CARBONATE
  • DISUCCINIMIDYL CARBONATE
  • DI-(N,N'-SUCCINIMIDYL) CARBONATE
  • DI(N-SUCCINIMIDYL) CARBONATE
  • LABOTEST-BB LT00847311
  • N-SUCCINIMIDYL CARBONATE
  • N,N'-DISUCCINIMIDYL CARBONATE
  • N'-Disuccinimidyl carbonate
  • Di(N-succinimidyl)Carbonate&gt
  • N,N''-Disuccinimidyl carbonate, Tech Grade
  • N,N'-Disuccinimidyl carbonate USP/EP/BP
  • N,N′-Disuccinimidyl Carbonate (Technical Grade)
  • Di-(N-Succinimidyl) Carbonate extrapure, 95%
  • N. N '- Disuccinimide carbonate
  • N,N' -dissuccinimide carbonate
  • N,N'-Disuccinimidyl carbonate
  • DSCN,N'-Disuccinimidyl carbonate
  • 74124-79-1