N,N'-Disuccinimidyl carbonate

Product Name: N,N'-Disuccinimidyl carbonate
CAS No.: 74124-79-1
Chemical Name: N,N'-Disuccinimidyl carbonate
Synonyms: DSC;Bis(2,5-dioxopyrrolidin-1-yl) carbonate;DISUCCINIMIDYL CARBONATE;SU2O;DI(SUCCINIMIDO) CARBONATE;DI(N-SUCCINIMIDYL) CARBONATE;BIS(N-SUCCINIMIDYL) CARBONATE;Carbonic acid bis-(2,5-dioxo-pyrrolidin-1-yl) ester;(SUO)2CO;DSCsee24500
CBNumber: CB3323388
Molecular Formula: C9H8N2O7
Formula Weight: 256.17
MOL File: 74124-79-1.mol

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N,N'-Disuccinimidyl carbonate Property

Melting point:: 190 °C (dec.)(lit.)
Boiling point:: 399.41°C (rough estimate)
Density: 1.5670 (rough estimate)
refractive index: 1.5600 (estimate)
storage temp.: -20°C
solubility: Dichloromethane (Slightly, Heated), DMSO
form: Crystalline Powder
color: White to slightly yellow
Water Solubility: Soluble in dimethyl sulfoxide, hot pyridine, acetonitrile and most organic solvents. Insoluble in water.
BRN: 1499137
Stability:: Moisture Sensitive
InChIKey: PFYXSUNOLOJMDX-UHFFFAOYSA-N
CAS DataBase Reference: 74124-79-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38
Safety Statements: 26-37/39-36
WGK Germany: 3
F: 10-21
TSCA: No
HS Code: 29299000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.51005
Product name: DSC
Purity: N,N′-Disuccinimidyl carbonate Novabiochem?
Packaging: 25g
Price: $222
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.51005
Product name: DSC
Purity: N,N′-Disuccinimidyl carbonate Novabiochem?
Packaging: 100g
Price: $660
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.14971
Product name: Di-(N,N′-succinimidyl) carbonate
Purity: for synthesis
Packaging: 5G
Price: $172
Updated: 2024/03/01

Sigma-Aldrich

Product number: 225827
Product name: N,N′-Disuccinimidyl carbonate
Purity: ≥95%
Packaging: 1g
Price: $25.74
Updated: 2024/03/01

Sigma-Aldrich

Product number: 225827
Product name: N,N′-Disuccinimidyl carbonate
Purity: ≥95%
Packaging: 5g
Price: $111
Updated: 2024/03/01

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N,N'-Disuccinimidyl carbonate Chemical Properties,Usage,Production

Chemical Properties

N,N'-Disuccinimidyl carbonate is white to slightly yellow crystalline powder

Uses

N,N'-Disuccinimidyl carbonate is a convenient reagent for the synthesis of N-succinimidyl esters of N-protected amino acids.

Uses

N,N’Disuccinimidyl Carbonate is a commonly used reagent for the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate, synthesis of urea, carbamates and coupling of lig ands to proteins. The coupling reagent property of N,N’Disuucinimidyl Carbonate speeds up coupling process, while reduces the loss of chiral integrity.

Uses

N,N'-Disuccinimidyl carbonate is used to prepare cleavable linker succinimide vinylsufonylethyl carbonate for thiol modified-DNA. It serves as a reagent for the synthesis of carbamates. Further, it is used as a coupling reagent as well as in the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate and coupling of ligand to proteins.

Synthesis Reference(s)

Tetrahedron Letters, 20, p. 4745, 1979 DOI: 10.1016/S0040-4039(01)86699-5

General Description

N,N′-Disuccinimidyl carbonate is used for the HPLC determination of amino compounds.

reaction suitability

reaction type: Coupling Reactions

N,N'-Disuccinimidyl carbonate Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N'-Disuccinimidyl carbonate Suppliers

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View Lastest Price from N,N'-Disuccinimidyl carbonate manufacturers

Hebei Mujin Biotechnology Co.,Ltd

Product: N,N'-Disuccinimidyl carbonate 74124-79-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-08-22

Baoji Guokang Bio-Technology Co., Ltd.

Product: N,N'-Disuccinimidyl carbonate 74124-79-1
Price: US $115.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1-10mt
Release date: 2021-06-03

Hebei Weibang Biotechnology Co., Ltd

Product: N,N'-Disuccinimidyl carbonate 74124-79-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2024-12-05

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TIMTEC-BB SBB005976

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