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6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID

Product Name
6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID
CAS No.
216955-75-8
Chemical Name
6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID
Synonyms
6-(1H-Imidazol-1-yl);6-IMIDAZOL-1-YL-NICOTINIC ACID;6-(1H-Imidazol-1-yl)nicotinicaci;6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID;6-imidazol-1-ylpyridine-3-carboxylic acid;6-(1H-imidazol-1-yl)-3-Pyridine carboxylic acid;3-Pyridinecarboxylic acid, 6-(1H-imidazol-1-yl)-;Pyridine,2,4-dichloro-, 1-oxide6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID;6-(1H-Imidazol-1-yl)pyridine-3-carboxylic acid, 1-(5-Carboxypyridin-2-yl)-1H-imidazole
CBNumber
CB2754404
Molecular Formula
C9H7N3O2
Formula Weight
189.17
MOL File
216955-75-8.mol
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6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID Property

Melting point:
>270°
Boiling point:
442.5±30.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
2.92±0.10(Predicted)
Appearance
White to off-white Solid
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
I577443
Product name
6-(1H-Imidazol-1-yl)nicotinicAcid
Packaging
500mg
Price
$200
Updated
2021/12/16
Matrix Scientific
Product number
043793
Product name
6-(1H-Imidazol-1-yl)nicotinic acid
Purity
>95%
Packaging
1g
Price
$228
Updated
2021/12/16
Matrix Scientific
Product number
043793
Product name
6-(1H-Imidazol-1-yl)nicotinic acid
Purity
>95%
Packaging
500mg
Price
$181
Updated
2021/12/16
SynQuest Laboratories
Product number
4H21-1-E5
Product name
6-(1H-Imidazol-1-yl)nicotinic acid
Packaging
1g
Price
$186
Updated
2021/12/16
AK Scientific
Product number
7379AD
Product name
6-(1H-Imidazol-1-yl)nicotinicacid
Packaging
1g
Price
$191
Updated
2021/12/16
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6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID Chemical Properties,Usage,Production

Synthesis

111205-01-7

216955-75-8

General procedure for the synthesis of 6-(1H-imidazol-1-yl)nicotinic acid from 6-(1H-imidazol-1-yl)nicotinic acid methyl ester: In a round-bottomed flask, 6-(1H-imidazol-1-yl)nicotinic acid methyl ester (535 mg, 2.50 mmol), tetrahydrofuran (12 mL), sodium hydroxide (780 mg, 19.50 mmol), and methanol (10 mL) were added, and the reaction was conducted at 50°C for 3 h. The reaction was heated at 50°C for 3 h. Upon completion of the reaction, the reaction mixture was acidified with 1N hydrochloric acid and subsequently concentrated to dryness under reduced pressure. The resulting solid was suspended in a mixed solvent of methanol/dichloromethane, filtered and concentrated to give 6-(1H-imidazol-1-yl)nicotinic acid as a white solid (0.47 g, 68% yield).LCMS (m/z): 190.0 (M + 1).

References

[1] Patent: WO2014/168824, 2014, A1. Location in patent: Page/Page column 39; 40
[2] Patent: WO2011/94890, 2011, A1. Location in patent: Page/Page column 130

6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID Suppliers

China 35 India 1 Ukraine 2 United Kingdom 3 United States 8 Global 49
Wuhan Chemwish Technology Co., Ltd
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View Lastest Price from 6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID manufacturers

Career Henan Chemica Co
Product
Pyridine,2,4-dichloro-, 1-oxide6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID 216955-75-8
Price
US $1.80/KG
Min. Order
1g
Purity
96%-99%
Supply Ability
1kg/10kg/100kg
Release date
2020-11-07

216955-75-8, 6-(1H-IMIDAZOL-1-YL)NICOTINIC ACIDRelated Search:

Picoxystrobin Lactofen 2-(4-ISOPROPYL-4-METHYL-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-NICOTINIC ACID METHYL 6-(1H-IMIDAZOL-1-YL)NICOTINATE 2-(4-ethyl-4-methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl)nicotinic acid 2-(2-methyl-1H-imidazol-1-yl)nicotinic acid 6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID 2-IMIDAZOL-1-YL-NICOTINIC ACID 5-Bromo-2-(1H-imidazol-1-yl)nicotinic acid 2-(1H-imidazol-1-yl)nicotinic acid 4-IMIDAZOL-1-YL-NICOTINIC ACID 5-chloro-6-(1H-imidazol-1-yl)nicotinic acid 6-(1H-benzimidazol-1-yl)nicotinic acid 5-chloro-6-(2-methyl-1H-imidazol-1-yl)nicotinic acid 6-(4-nitro-1H-imidazol-1-yl)pyridine-3-carboxylic acid 5-bromo-6-(1h-imidazol-1-yl)nicotinic acid 6-(2-methyl-1H-imidazol-1-yl)nicotinic acid 6-[2-(propan-2-yl)-1H-imidazol-1-yl]pyridine-3-carboxylic acid

  • 6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID
  • 6-IMIDAZOL-1-YL-NICOTINIC ACID
  • 6-(1H-Imidazol-1-yl)pyridine-3-carboxylic acid, 1-(5-Carboxypyridin-2-yl)-1H-imidazole
  • 6-imidazol-1-ylpyridine-3-carboxylic acid
  • 6-(1H-imidazol-1-yl)-3-Pyridine carboxylic acid
  • 6-(1H-Imidazol-1-yl)
  • Pyridine,2,4-dichloro-, 1-oxide6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID
  • 3-Pyridinecarboxylic acid, 6-(1H-imidazol-1-yl)-
  • 6-(1H-Imidazol-1-yl)nicotinicaci
  • 216955-75-8
  • Carboxylic Acids
  • Pyridines
  • Carboxylic Acids