3-DEAZA-2'-DEOXYADENOSINE
- Product Name
- 3-DEAZA-2'-DEOXYADENOSINE
- CAS No.
- 78582-17-9
- Chemical Name
- 3-DEAZA-2'-DEOXYADENOSINE
- Synonyms
- Aids002055;Aids-002055;3-Deaza-2'-da;3'-Deazaadenosine;3-Deaza-2'-deoxyadenosine;3-Deaza-2'-deoxyadenosine;1H-Imidazo[4,5-c]pyridin-4-amine, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-;1-(2-Deoxy-β-D-erythro -pentofuranosyl)-1H - imidazo[4,5-c ]pyridin-4-amine;1H-Imidazo[4,5-C]pyridin-4-amine, 1-(2'-deoxy-.beta.-D-erythro-pentofuranosyl)-
- CBNumber
- CB2763394
- Molecular Formula
- C11H14N4O3
- Formula Weight
- 250.25
- MOL File
- 78582-17-9.mol
3-DEAZA-2'-DEOXYADENOSINE Property
- Melting point:
- 208-209 °C
- Boiling point:
- 617.7±65.0 °C(Predicted)
- Density
- 1.75±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 5 mg/ml; DMSO: 20 mg/ml; PBS (pH 7.2): 10 mg/ml
- form
- A crystalline solid
- pka
- 13.88±0.60(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 9000786
- Product name
- 3-Deaza-2'-deoxyadenosine
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $48
- Updated
- 2024/03/01
- Product number
- 9000786
- Product name
- 3-Deaza-2'-deoxyadenosine
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $210
- Updated
- 2024/03/01
- Product number
- 9000786
- Product name
- 3-Deaza-2'-deoxyadenosine
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $371
- Updated
- 2024/03/01
- Product number
- 9000786
- Product name
- 3-Deaza-2'-deoxyadenosine
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $807
- Updated
- 2024/03/01
- Product number
- ND57491
- Product name
- 3-Deaza-2'-Deoxyadenosine
- Packaging
- 25mg
- Price
- $87.5
- Updated
- 2021/12/16
3-DEAZA-2'-DEOXYADENOSINE Chemical Properties,Usage,Production
Uses
3-Deaza-2 '-deoxyadenosine is a nucleoside analog synthesized from 2' -deoxyadenosine. 3-Deaza-2 '-deoxyadenosine inhibits RNA synthesis by binding to ribose fragments of ribonucleotides, thereby preventing the formation of enzyme-substrate complexes, thereby preventing chain elongation, It can also inhibit DNA synthesis by binding deoxyribose fragments of DNA and preventing DNA polymerase from adding nucleotides to the growth chain. 3-Deaza-2 '-deoxyadenosine has antiviral activity[1][2].
References
[1] Hendrickson CL, et al. Probing minor groove recognition contacts by DNA polymerases and reverse transcriptases using 3-deaza-2'-deoxyadenosine. Nucleic Acids Res. 2004 Apr 23;32(7):2241-50. DOI:10.1093/nar/gkh542
[2] Cristalli G, et al. Synthesis and biological evaluation of N6-cycloalkyl derivatives of 1-deazaadenine nucleosides: a new class of anti-human immunodeficiency virus agents. J Med Chem. 1995 Sep 29;38(20):4019-25. DOI:10.1021/jm00020a017
3-DEAZA-2'-DEOXYADENOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-DEAZA-2'-DEOXYADENOSINE manufacturers
- Product
- 3-DEAZA-2'-DEOXYADENOSINE 78582-17-9
- Price
- US $0.00-0.00/G
- Min. Order
- 1G
- Purity
- 97%
- Supply Ability
- 2000
- Release date
- 2025-05-30