Nalpha-Cbz-L-Arginine

Product Name: Nalpha-Cbz-L-Arginine
CAS No.: 1234-35-1
Chemical Name: Nalpha-Cbz-L-Arginine
Synonyms: Z-ARG;z-aga-oh;Z-ARG-OH;CBZ-L-Arg;CBZ-ARG-OH;Z-ARGININE;Z-L-ARG-OH;CBZ-L-ARG-OH;Z-L-ARGININE;CBZ-L-ARGNINE
CBNumber: CB2768142
Molecular Formula: C14H20N4O4
Formula Weight: 308.33
MOL File: 1234-35-1.mol

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Nalpha-Cbz-L-Arginine Property

Melting point:: 171-174 °C (dec.)(lit.)
alpha: -11 º (c=0.5, 0.5N HCl 24 ºC)
Boiling point:: 448.73°C (rough estimate)
Density: 1.1765 (rough estimate)
refractive index: -10 ° (C=5.5, 0.2mol/L HCl)
storage temp.: 2-8°C
solubility: DMSO, Water
form: Solid
pka: 3.90±0.21(Predicted)
color: White
optical activity: [α]20/D 9±1°, c = 5% in 1 M HCl
BRN: 2169267
CAS DataBase Reference: 1234-35-1(CAS DataBase Reference)
EPA Substance Registry System: L-Arginine, N2-[(phenylmethoxy)carbonyl]- (1234-35-1)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 24/25-36-26-S24/25
WGK Germany: 3
TSCA: Yes
HS Code: 29252900

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 95930
Product name: Z-Arg-OH
Purity: ≥96.0% (NT)
Packaging: 5g
Price: $42.5
Updated: 2022/05/15

TCI Chemical

Product number: C0757
Product name: Nalpha-Carbobenzoxy-L-arginine
Purity: >97.0%(T)
Packaging: 1g
Price: $35
Updated: 2025/07/31

TCI Chemical

Product number: C0757
Product name: Nalpha-Carbobenzoxy-L-arginine
Purity: >97.0%(T)
Packaging: 25g
Price: $93
Updated: 2025/07/31

TRC

Product number: A769400
Product name: Z-L-Arginine
Packaging: 10g
Price: $55
Updated: 2021/12/16

TRC

Product number: A769400
Product name: Z-L-Arginine
Packaging: 100g
Price: $225
Updated: 2021/12/16

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Nalpha-Cbz-L-Arginine Chemical Properties,Usage,Production

Chemical Properties

white powder

Uses

Z-L-Arginine is used in the synthesis of renin inhibitors containing phosphorous acid derivatives at the scissile bond. Also used in the synthesis of a peptide deformylase inhibitor BB-3497.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

420-04-2

2640-58-6

1234-35-1

The general procedure for the synthesis of Cbz-arginine from cyanamide and (S)-5-amino-2-(benzyloxycarbonyloxyamino)pentanoic acid was as follows: to a solution of water (2.5 mL) containing p-methoxyaniline (1b, 61.6 mg, 0.50 μmol) and cyanamide (25.2 mg, 0.60 μmol) was added scandium trifluoromethanesulfonate (Sc(OTf)3, at room temperature. 24.6 mg, 50 nmol). The reaction mixture was stirred at 100 °C for 2 days. After completion of the reaction, the reaction mixture was washed with chloroform (3 x 10 mL) extraction. The aqueous layer was separated and concentrated under vacuum. The residue was purified by filtration through a silica gel pad (eluent: chloroform-methanol, 20:1, v/v).

References

[1] Synlett, 2014, vol. 25, # 9, p. 1302 - 1306

Nalpha-Cbz-L-Arginine Preparation Products And Raw materials

Raw materials

Preparation Products

N-Phospho-L-arginine PHOSPHO-L-ARGININE SODIUM

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Nalpha-Cbz-L-Arginine Suppliers

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View Lastest Price from Nalpha-Cbz-L-Arginine manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Cbz-Arg-OH 1234-35-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2023-12-29

Shaanxi Dideu Medichem Co. Ltd

Product: Nalpha-Cbz-L-Arginine 1234-35-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 10000KG
Release date: 2024-08-08

Career Henan Chemical Co

Product: Nalpha-Cbz-L-Arginine 1234-35-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-15

1234-35-1, Nalpha-Cbz-L-ArginineRelated Search:

Cbz-L-arginine hydrochloride Benzyloxyacetyl chloride L(+)-Arginine ARGINASE Trimethoprim Z-ARG-OH HCL Arginine Z-ARG(MTR)-OH CHA Z-ARG(NO2)-OH Z-ARG(Z)2-OH BOC-ARG(Z)-OH BPOC-ARG(MTR)-OH Z-ARG(MTR)-OTBU N-ALPHA-BENZYLOXYCARBONYL-N'-2,2,4,6,7-PENTAMETHYLDIHYDROBENZOFURAN-5-SULFONYL-L-ARGININE CYCLOHEXYLAMINE Z-ARG(PMC)-OME 2-ARG-OBZL(4-NO2)HYDROCHLORIDE AND HYDROBROMIDE Z-ARG(MBS)-OH DCHA Z-ARG(TOS)-OH CHA

n2-[(phenylmethoxy)carbonyl]-l-arginin

BenzyloxycarbonylLarginine

N(alpha)-Benzyloxycarbonyl-L-arginine~Z-Arg-OH

Na-Benzyloxycarbonyl-L-arginine

na-cbz-L-arginine free acid

N2-[(phenylmethoxy)carbonyl]-L-arginine

N<sub>α</sub>-Z-L-Arginine

N<sup>2</sup>-Carbobenzyloxy-L-arginine

N-α-Z-L-arginine

N-Carbobenzyloxy-L-arginine

Nɑ-Benzyloxycarbonyl-L-arginine, 99%

Nalpha-Cbz-L-Arginin

CBZ-L-ARGNINE

n(à)-cbz-l-arginine

nà-benzyloxycarbonyl-l-arginine

z-aga-oh

Z-ARG

N-BENZYLOXYCARBONYL-L-ARGININE(Z-ARG-OH)

CBZ-L-Arg

CBZ-L-Arginine (Z-Arg-OH)

Nalpha-Cbz-L-arginine Z-Arg-OH

(S)-2-(((benzyloxy)carbonyl)aMino)-5-guanidinopentanoic acid

Nalpha-Carbobenzyl

Z-L-arginine≥ 99% (HPLC)

(2S)-5-(diaminomethylideneammonio)-2-(phenylmethoxycarbonylamino)pentanoate

(2S)-2-{[(benzyloxy)carbonyl]amino}-5-carbamimidamidopentanoic acid

Nalpha-Carbobenzyloxy-L-arginine, 98.5%

Z-L-ARGININE extrapure

N(sup 2)-carbobenzyloxy-L-arginine

Nα-Z-L-Arginine, N2-Carbobenzyloxy-L-arginine

CBZ-ARG-OH

CBZ-L-ARGININE

CBZ-L-ARG-OH

N-BENZYLOXYCARBONYL-L-ARGININE

N-ALPHA-BENZYLOXYCARBONYL-L-ARGININE

Z-ARG-OH

Z-ARGININE

Z-L-ARGININE

Z-L-ARG-OH

L-ARGININE, N2-[(PHENYLMETHOXY)CARBONYL]-

Nα-Carbobenzoxy-L-arginine ,98%

N-CBZ-L-ARGININE-OH

N2-CARBOBENZYLOXY-L-ARGININE

NALPHA-CBZ-L-ARGININE

N-ALPHA-CARBOBENZYLOXY-L-ARGININE

NALPHA-CARBOBENZOXY-L-ARGININE

N-ALPHA-Z-L-ARGININE

N-CARBOBENZOXY-L-ARGININE

(2S)-5-(Diaminomethylideneamino)-2-(phenylmethoxycarbonylamino)pentanoic acid

(S)-2-(Benzyloxycarbonylamino)-5-(amidinoamino)valeric acid

Nα-(Benzyloxycarbonyl)arginine

Nα-Cbz-L-Arg-OH

Nalpha-Carbobenzyloxy-L-arginine,98%

Nα-Carbobenzoxy-L-arginine &gt

Nalpha-Cbz-L-Arginine USP/EP/BP

Nα-Carbobenzoxy-L-arginine

Nα -Cbz-L-arginine, 99% [Z-Arg-OH]

1234-35-1