ChemicalBook > CAS DataBase List > 2-METHOXY-3-NITRO-4-PICOLINE

2-METHOXY-3-NITRO-4-PICOLINE

Product Name
2-METHOXY-3-NITRO-4-PICOLINE
CAS No.
160590-36-3
Chemical Name
2-METHOXY-3-NITRO-4-PICOLINE
Synonyms
SKL431;2-METHOXY-3-NITRO-4-PICOLINE;2-methoxy-3-nitro-4-methylpyridine;Pyridine,2-Methoxy-4-Methyl-3-nitro-;2-METHOXY-3-NITRO-4-PICOLINE ISO 9001:2015 REACH
CBNumber
CB2771373
Molecular Formula
C7H8N2O3
Formula Weight
168.15
MOL File
160590-36-3.mol
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2-METHOXY-3-NITRO-4-PICOLINE Property

Melting point:
38-40℃
Boiling point:
270℃
Density 
1.247
Flash point:
117℃
storage temp. 
Sealed in dry,Room Temperature
pka
0.02±0.18(Predicted)
Appearance
Yellow to brown Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M327208
Product name
2-Methoxy-3-nitro-4-picoline
Packaging
100mg
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
101348
Product name
2-Methoxy-4-methyl-3-nitropyridine
Purity
98%
Packaging
1g
Price
$54
Updated
2021/12/16
Matrix Scientific
Product number
101348
Product name
2-Methoxy-4-methyl-3-nitropyridine
Purity
98%
Packaging
5g
Price
$175
Updated
2021/12/16
AK Scientific
Product number
W3484
Product name
2-Methoxy-3-nitro-4-methylpyridine
Packaging
5g
Price
$286
Updated
2021/12/16
Matrix Scientific
Product number
101348
Product name
2-Methoxy-4-methyl-3-nitropyridine
Purity
98%
Packaging
10g
Price
$290
Updated
2021/12/16
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2-METHOXY-3-NITRO-4-PICOLINE Chemical Properties,Usage,Production

Synthesis

23056-39-5

124-41-4

160590-36-3

A solution was prepared by dissolving 2-chloro-4-methyl-3-nitropyridine (250 g, 1.45 mol) in methanol (1.0 L). This solution was slowly added dropwise (taking 2 hours) to a stirring solution of sodium methanolate (250 μL, 4.63 mol) in methanol (850 mL) at 0 °C. After the dropwise addition, the reaction mixture was heated to reflux and maintained for 23 h, during which time the progress of the reaction was monitored by thin-layer chromatography (TLC) to confirm the completion of the reaction. Upon completion of the reaction, the mixture was concentrated to about 900 mL under reduced pressure, followed by the addition of water (1.5 L) to quench the reaction. The precipitated solid product was collected by filtration, washed with water and dried under reduced pressure to afford 2-methoxy-3-nitro-4-methylpyridine (250 g, 100% yield) as a brown solid. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 8.22 (d, J = 5.2 Hz, 1H), 7.10 (d, J = 5.6 Hz, 1H), 3.92 (s, 3H), 2.26 (s, 3H).

References

[1] Patent: WO2016/77378, 2016, A1. Location in patent: Page/Page column 85; 157; 158; 163; 164
[2] Patent: WO2016/77380, 2016, A1. Location in patent: Page/Page column 63
[3] Patent: WO2016/77375, 2016, A1. Location in patent: Page/Page column 79
[4] Patent: WO2016/123391, 2016, A1. Location in patent: Page/Page column 76; 185; 186
[5] Journal of Organic Chemistry, 2001, vol. 66, # 17, p. 5723 - 5730

2-METHOXY-3-NITRO-4-PICOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-METHOXY-3-NITRO-4-PICOLINE Suppliers

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View Lastest Price from 2-METHOXY-3-NITRO-4-PICOLINE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-METHOXY-3-NITRO-4-PICOLINE 160590-36-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-30
Henan Fengda Chemical Co., Ltd
Product
2-METHOXY-3-NITRO-4-PICOLINE 160590-36-3
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Dideu Industries Group Limited
Product
2-METHOXY-3-NITRO-4-PICOLINE 160590-36-3
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-27