HYPOCRELLIN A

Product Name: HYPOCRELLIN A
CAS No.: 77029-83-5
Chemical Name: HYPOCRELLIN A
Synonyms: 11-epoxide;HYPOCRELLIN;HYPOCRELLIN A;Hycrecrellin A;Dexamethasone 9;(1S,2R)-1-acetyl-2,5,12-trihydroxy-4,8,9,13-tetramethoxy-2-m...;11-Acetyl-3,8,12-trihydroxy-1,5,6,10-tetramethoxy-12-methyl-12,13-dihydro-2H-cyclohepta[ghi]perylene-2,9(11H)-dione;(1S,2R)-1-acetyl-2,5,12-trihydroxy-4,8,9,13-tetramethoxy-2-methyl-2,3-dihydro-1H-cyclohepta[ghi]perylene-6,11-dione;1H-Cyclohepta[ghi]perylene-5,12-dione,1-acetyl-2,3-dihydro-2,6,11-trihydroxy-4,8,9,13-tetramethoxy-2-methyl-,stereoisomer;(11R,12S)-11-acetyl-3,9,12-trihydroxy-1,5,6,10-tetramethoxy-12-methyl-12,13-dihydro-2H-cyclohepta[ghi]perylene-2,8(11H)-dione
CBNumber: CB2772800
Molecular Formula: C30H26O10
Formula Weight: 546.52
MOL File: 77029-83-5.mol

More

Less

HYPOCRELLIN A Property

Melting point:: 209-210 °C
Boiling point:: 922.8±65.0 °C(Predicted)
Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 2mg/mL; DMSO: 3mg/mL; Ethanol: 0.3mg/mL
form: A solid
pka: 7.03±0.60(Predicted)
color: Brown to red
InChIKey: URTOHKHBNYPGQJ-UHYDGBJBNA-N
SMILES: C12C3[C@@H](C(=O)C)[C@](O)(C)CC4=C(C(=O)C5=C(C=C(OC)C(C6C(OC)=CC(=O)C(=C(O)C=3OC)C1=6)=C5C=24)O)OC |&1:2,6,r|

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 29933
Product name: Hypocrellin A
Packaging: 1mg
Price: $86
Updated: 2024/03/01

Cayman Chemical

Product number: 29933
Product name: Hypocrellin A
Packaging: 25mg
Price: $838
Updated: 2024/03/01

Cayman Chemical

Product number: 29933
Product name: Hypocrellin A
Packaging: 5mg
Price: $296
Updated: 2024/03/01

Cayman Chemical

Product number: 29933
Product name: Hypocrellin A
Packaging: 10mg
Price: $463
Updated: 2024/03/01

Usbiological

Product number: 300447
Product name: hypocrellin A
Packaging: 10mg
Price: $546
Updated: 2021/12/16

More

Less

HYPOCRELLIN A Chemical Properties,Usage,Production

Chemical Properties

Red crystal, odorless, tasteless, purity 98%, melting point 209-210 ℃, soluble in chloroform, acetone, ethyl acetate, soluble in methanol, ethanol, slightly soluble in petroleum ether, insoluble in water, not easy to hydrolysis, but in the alkaline environment can be self-sensitive photo-oxidation of photolysis; now the folk used as a drug to treat gastric pain and arthritis and is the treatment of dermatological disorders, anti-tumor, anti-AIDS, the potentially effective It is also a potentially effective photosensitive drug for the treatment of skin diseases, anti-tumor and anti-AIDS.

Uses

Hypocrellin A is an antimicrobial and antileishmanial activity. Ga(3+)-Hypocrellin interacts with myoglobin in vitro.

in vivo

Hypocrellin A (2.5 and 5 mg/kg; i.p.; once every two days for fourteen days) inhibits tumor growth in a non-small cell lung cancer xenograft model mouse model^[8].

Animal Model:	H460 cells were inoculated subcutaneously on the backs of BALB/c nude mice^[8]
Dosage:	2.5 and 5 mg/kg
Administration:	i.p.; Inject once every two days for fourteen days
Result:	Induced the expression of the pro-apoptotic protein BAX and inhibited the expression of the anti-apoptotic protein BCL-2 in NSCLC tumors.

IC 50

Leishmania

HYPOCRELLIN A Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

HYPOCRELLIN A Suppliers

China 129 Switzerland 1 United Kingdom 3 United States 16 Global 149

Huzhou ZhanShu Biotechnology Co.,Ltd

Tel: 0572-8889530 18167260939
Email: zsubio@163.com
Country: China
ProdList: 392
Advantage: 58

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5653
Advantage: 65

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4999
Advantage: 60

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

Chengdu Herbpurify Co.Ltd.

Tel: 2355253622; 18981954830
Fax: 086-28-85377358
Email: 2355253622@qq.com;
Country: China
ProdList: 1103
Advantage: 58

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

More

Less

View Lastest Price from HYPOCRELLIN A manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Hypocrellin A 77029-83-5
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥95%(HPLC)
Supply Ability: 10 g
Release date: 2020-02-25

Longyan Tianhua Biological Technology Co., Ltd

Product: HYPOCRELLIN A 77029-83-5
Price: US $30.00/Kg/Bag
Min. Order: 25Kg/Bag
Purity: 99%
Supply Ability: 20 Tons
Release date: 2020-11-17

77029-83-5, HYPOCRELLIN ARelated Search:

HYPOCRELLIN B, HYPOCRELLA BAMBUSAE,HYPOCRELLIN B Sineptina oleandomycin Raddeanin(Anemodeanin) A podocarpusflavone A Chikusetsusaponin V methyl ester 2-(4-Methoxyphenyl)-5,7-dihydroxy-8-[2-hydroxy-5-(4-oxo-5-hydroxy-7-methoxy-4H-1-benzopyran-2-yl)phenyl]-4H-1-benzopyran-4-one (1S)-1,2,3,3a,5aβ,6,10b,10cβ-Octahydro-1,2α,6α-trihydroxy-3aβ,10bα-dimethyl-7-isopropyl-4H,9H-furo[2',3',4':4,5]naphtho[2,1-c]pyran-4,9-dione (+)-Xanthoplanine Hypocrellin C chikusetsu saponin IVa 9,10-DIMETHYLANTHRACENE 9-Anthracenemethanol 4'-(2-Methylpropyl)acetophenone 9-VINYLANTHRACENE 1,3-DIHYDROXYNAPHTHALENE 2-Naphthaleneethanol 2,3-Dihydroxynaphthalene

HYPOCRELLIN

HYPOCRELLIN A

1H-Cyclohepta[ghi]perylene-5,12-dione,1-acetyl-2,3-dihydro-2,6,11-trihydroxy-4,8,9,13-tetramethoxy-2-methyl-,stereoisomer

(1S,2R)-1-acetyl-2,5,12-trihydroxy-4,8,9,13-tetramethoxy-2-methyl-2,3-dihydro-1H-cyclohepta[ghi]perylene-6,11-dione

(11R,12S)-11-acetyl-3,9,12-trihydroxy-1,5,6,10-tetramethoxy-12-methyl-12,13-dihydro-2H-cyclohepta[ghi]perylene-2,8(11H)-dione

(1S,2R)-1-acetyl-2,5,12-trihydroxy-4,8,9,13-tetramethoxy-2-m...

11-epoxide

Dexamethasone 9

11-Acetyl-3,8,12-trihydroxy-1,5,6,10-tetramethoxy-12-methyl-12,13-dihydro-2H-cyclohepta[ghi]perylene-2,9(11H)-dione

Hycrecrellin A

77029-83-5

C30H26O10