ChemicalBook > CAS DataBase List > 4'-(2-Methylpropyl)acetophenone

4'-(2-Methylpropyl)acetophenone

Product Name
4'-(2-Methylpropyl)acetophenone
CAS No.
38861-78-8
Chemical Name
4'-(2-Methylpropyl)acetophenone
Synonyms
1-(4-ISOBUTYLPHENYL)ETHAN-1-ONE;4-ISOBUTYLACETOPHENONE;1-(4-ISOBUTYLPHENYL)ETHANONE;4-IBAP;Nsc173015;1Y1&1R DV1;Ibuprofen-4;IBUPROFEN IMP E;p-Isobutylacetoph;TIMTEC-BB SBB007668
CBNumber
CB3210390
Molecular Formula
C12H16O
Formula Weight
176.25
MOL File
38861-78-8.mol
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4'-(2-Methylpropyl)acetophenone Property

Boiling point:
134-135°C 16mm
Density 
0,952 g/cm3
vapor pressure 
0.75Pa at 20℃
refractive index 
1.5180
Flash point:
54°C
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Dichloromethane; Diethyl Ether; Ethyl Acetate; THF
color 
Colorless to Yellow
Water Solubility 
Miscible with chloroform and methanol. Slightly miscible with water.
BRN 
1935275
InChI
InChI=1S/C12H16O/c1-9(2)8-11-4-6-12(7-5-11)10(3)13/h4-7,9H,8H2,1-3H3
InChIKey
KEAGRYYGYWZVPC-UHFFFAOYSA-N
SMILES
C(=O)(C1=CC=C(CC(C)C)C=C1)C
LogP
3.4 at 23℃
CAS DataBase Reference
38861-78-8(CAS DataBase Reference)
NIST Chemistry Reference
4'-(2-Methylpropyl)acetophenone(38861-78-8)
EPA Substance Registry System
Ethanone, 1-[4-(2-methylpropyl)phenyl]- (38861-78-8)
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Safety

Hazard Codes 
Xn,N,Xi
Risk Statements 
10-40-52/53-43
Safety Statements 
16-36-22-61-36/37
RIDADR 
1224
WGK Germany 
3
TSCA 
Yes
HazardClass 
3.2
PackingGroup 
III
HS Code 
29143990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR1146
Product name
4′-Isobutylacetophenone
Packaging
500mg
Price
$128
Updated
2024/03/01
Sigma-Aldrich
Product number
BP557
Product name
4′-Isobutylacetophenone
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
100MG
Price
$222
Updated
2024/03/01
Sigma-Aldrich
Product number
1335541
Product name
Ibuprofen Related Compound C
Packaging
3x0.2ml
Price
$1380
Updated
2024/03/01
TCI Chemical
Product number
I0417
Product name
4'-Isobutylacetophenone
Purity
>96.0%(GC)
Packaging
25mL
Price
$72
Updated
2024/03/01
TCI Chemical
Product number
I0417
Product name
4'-Isobutylacetophenone
Purity
>96.0%(GC)
Packaging
100mL
Price
$197
Updated
2024/03/01
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4'-(2-Methylpropyl)acetophenone Chemical Properties,Usage,Production

Chemical Properties

Clear Colourless Oil

Uses

4'-isobutylacetophenone is an important starting material employed in the production of pharmaceuticals such as ibuprofen. It is also utilized in proteomics research. It is used as an intermediate in organic synthesis.

Uses

A degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy.

Preparation

Synthesis of 4-isobutylacetophenone: toluene and propylene are reacted with the participation of metal potassium, sodium carbonate and graphite, Alkylation on methyl to generate isobutylbenzene, Then with acetyl chloride in the participation of anhydrous aluminum trichloride to obtain the product.

General Description

4'-(2-Methylpropyl)acetophenone, also known as Ibuprofen EP Impurity E, is an impurity of ibuprofen. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation.

4'-(2-Methylpropyl)acetophenone Preparation Products And Raw materials

Raw materials

Isobutylbenzene Aluminum chloride Potassium Graphite

Preparation Products

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4'-(2-Methylpropyl)acetophenone Suppliers

Americas 1 Belgium 2 Canada 2 China 237 Europe 3 France 1 Germany 4 India 43 Japan 2 Norway 1 Ukraine 1 United Kingdom 17 United States 41 Global 355
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
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Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
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View Lastest Price from 4'-(2-Methylpropyl)acetophenone manufacturers

Hebei Mojin Biotechnology Co., Ltd
Product
4'-(2-Methylpropyl)acetophenone 38861-78-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2024-10-30
Hebei Mojin Biotechnology Co.,Ltd
Product
4'-(2-Methylpropyl)acetophenone 38861-78-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-09-27
Hebei Weibang Biotechnology Co., Ltd
Product
4'-(2-Methylpropyl)acetophenone 38861-78-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2022-09-30

38861-78-8, 4'-(2-Methylpropyl)acetophenoneRelated Search:

Ibuprofen 1-Hydroxyibuprofen (S)-(+)-Ibuprofen 1-Oxo Ibuprofen Ibuprofen Ethyl Ester 2-[4-(2-Methylpropyl)phenyl] ethanol 6-isobutyl-3-methyl-2,3-dihydro-1H-inden-1-one 2-(4-Methylphenyl)propanoic acid (2RS)-2-(4-BUTYLPHENYL)PROPANOIC ACID rac 2-Hydroxy Ibuprofen 4-(2-Methylpropyl)benzeneethanol (R)-(-)-IBUPROFEN Ibuprofen EP Impurity I 3-(4-ISOBUTYL-PHENYL)-PROPIONIC ACID p-Isobutylstyrene rac-Ibuprofen amide rac a-Hydroxy Ibuprofen (2RS)-2-(4-FORMYLPHENYL)PROPANOIC ACID Ibuprofen Impurity E

  • Imp. E:1-(4-isobutylphenyl)ethanone
  • TIMTEC-BB SBB007668
  • P-ISO-BUTYLACETOPHENONE
  • IBUPROFEN IMPURITY E
  • IBUPROFEN IMP E
  • ISOBUTYL ACETOPHENONE
  • 4'-Isobutylacetophenone, 97+%
  • 4'-ISOBUTYLACETOPHENONE
  • 4-ISOBUTYLACETOPHENONE
  • 1-[4-(2-METHYLPROPYL)PHENYL]ETHANONE
  • 1-(4-ISOBUTYLPHENYL)ETHAN-1-ONE
  • 1-(4-ISOBUTYLPHENYL)ETHANONE
  • 1-[4-(2-methylpropyl)phenyl]-ethanon
  • 4-Isobutylacetaphenone
  • 1-[4-(2-methylpropyl)phenyl]ethan-1-one
  • 1-(4-(2-METHYLPROPYL)PHENYL)ETNANONE
  • 4'-(2-Methylpropyl)acetophenone
  • 4-lsobutylacetophenone
  • Acetophenone, 4-isobutyl-
  • Ethanone, 1-[4-(2-methylpropyl)phenyl]-
  • Nsc173015
  • p-Isobutylacetoph
  • Ibuprofen IMpurity-E(EP)
  • 4'-(2-Methylpropyl)a
  • 1-[4-(2-Methylprop-1-yl)phenyl]ethan-1-one, 1-(4-Isobutylphenyl)ethan-1-one
  • Ibuprofen Related CoMpound C, USP
  • 3 ampules) (4-isobutylacetophenone)
  • 4-ISOBUTYLACETOPHENONE(Ibuprofen Related Compound C)(Ibuprofen Impurity E)
  • 1Y1&1R DV1
  • Ibuprofen-4
  • Ibuprofen Related Compound C (0.2 mL/ampule
  • 1-[4-(2-Methylpropyl)phenyl]-1-ethanone
  • 1-Acetyl-4-isobutylbenzene
  • p-Acetylisobutylbenzene
  • Ibuprofen EP Impurity E
  • 4-IBAP
  • Ibuprofen USP Related Compound C
  • Ibuprofen EP Impurity E：Ibuprofen Impurity E
  • 4'-Isobutylacetophenone&gt
  • 4-Isobutylacetophenone（Ibuprofen Impurity）
  • Ibuprofen Impurity 5（Ibuprofen EP Impurity E）
  • Ibuprofen Impurity E/4-isobutylacetophenone
  • Ibuprofen EP Impurity E/ Ibuprofen Related Compound C
  • Ibuprofen USP Related Compound CQ: What is Ibuprofen USP Related Compound C Q: What is the CAS Number of Ibuprofen USP Related Compound C Q: What is the storage condition of Ibuprofen USP Related Compound C Q: What are the applications of Ibuprofen USP Related Compound C
  • Ibuprofen EP Impurit
  • 4'-Isobutylacetophenone, ≥ 96.0%
  • 4’-Isobutylacetophenone
  • 4'-(2-Methylpropyl)acetophenone
  • 38861-78-8
  • Aromatic Acetophenones & Derivatives (substituted)
  • Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Aromatics
  • Impurities
  • Intermediates & Fine Chemicals
  • Pharmaceuticals