ChemicalBook > CAS DataBase List > 4'-(2-Methylpropyl)acetophenone

4'-(2-Methylpropyl)acetophenone

Product Name
4'-(2-Methylpropyl)acetophenone
CAS No.
38861-78-8
Chemical Name
4'-(2-Methylpropyl)acetophenone
Synonyms
1-(4-ISOBUTYLPHENYL)ETHAN-1-ONE;4-ISOBUTYLACETOPHENONE;1-(4-ISOBUTYLPHENYL)ETHANONE;4-IBAP;Nsc173015;1Y1&1R DV1;Ibuprofen-4;IBUPROFEN IMP E;p-Isobutylacetoph;TIMTEC-BB SBB007668
CBNumber
CB3210390
Molecular Formula
C12H16O
Formula Weight
176.25
MOL File
38861-78-8.mol
More
Less

4'-(2-Methylpropyl)acetophenone Property

Boiling point:
134-135°C 16mm
Density 
0,952 g/cm3
vapor pressure 
0.75Pa at 20℃
refractive index 
1.5180
Flash point:
54°C
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Dichloromethane; Diethyl Ether; Ethyl Acetate; THF
color 
Colorless to Yellow
Water Solubility 
Miscible with chloroform and methanol. Slightly miscible with water.
BRN 
1935275
InChI
InChI=1S/C12H16O/c1-9(2)8-11-4-6-12(7-5-11)10(3)13/h4-7,9H,8H2,1-3H3
InChIKey
KEAGRYYGYWZVPC-UHFFFAOYSA-N
SMILES
C(=O)(C1=CC=C(CC(C)C)C=C1)C
LogP
3.4 at 23℃
CAS DataBase Reference
38861-78-8(CAS DataBase Reference)
NIST Chemistry Reference
4'-(2-Methylpropyl)acetophenone(38861-78-8)
EPA Substance Registry System
Ethanone, 1-[4-(2-methylpropyl)phenyl]- (38861-78-8)
More
Less

Safety

Hazard Codes 
Xn,N,Xi
Risk Statements 
10-40-52/53-43
Safety Statements 
16-36-22-61-36/37
RIDADR 
1224
WGK Germany 
3
TSCA 
Yes
HazardClass 
3.2
PackingGroup 
III
HS Code 
29143990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR1146
Product name
4′-Isobutylacetophenone
Packaging
500mg
Price
$128
Updated
2024/03/01
Sigma-Aldrich
Product number
BP557
Product name
4′-Isobutylacetophenone
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
100MG
Price
$222
Updated
2024/03/01
Sigma-Aldrich
Product number
1335541
Product name
Ibuprofen Related Compound C
Packaging
3x0.2ml
Price
$1380
Updated
2024/03/01
TCI Chemical
Product number
I0417
Product name
4'-Isobutylacetophenone
Purity
>96.0%(GC)
Packaging
25mL
Price
$72
Updated
2024/03/01
TCI Chemical
Product number
I0417
Product name
4'-Isobutylacetophenone
Purity
>96.0%(GC)
Packaging
100mL
Price
$197
Updated
2024/03/01
More
Less

4'-(2-Methylpropyl)acetophenone Chemical Properties,Usage,Production

Chemical Properties

Clear Colourless Oil

Uses

4'-isobutylacetophenone is an important starting material employed in the production of pharmaceuticals such as ibuprofen. It is also utilized in proteomics research. It is used as an intermediate in organic synthesis.

Uses

A degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy.

Preparation

Synthesis of 4-isobutylacetophenone: toluene and propylene are reacted with the participation of metal potassium, sodium carbonate and graphite, Alkylation on methyl to generate isobutylbenzene, Then with acetyl chloride in the participation of anhydrous aluminum trichloride to obtain the product.

General Description

4'-(2-Methylpropyl)acetophenone, also known as Ibuprofen EP Impurity E, is an impurity of ibuprofen. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation.

4'-(2-Methylpropyl)acetophenone Preparation Products And Raw materials

Raw materials

Isobutylbenzene Aluminum chloride Potassium Graphite

Preparation Products

More
Less

4'-(2-Methylpropyl)acetophenone Suppliers

Americas 1 Belgium 2 Canada 2 China 237 Europe 3 France 1 Germany 4 India 43 Japan 2 Norway 1 Ukraine 1 United Kingdom 17 United States 41 Global 355
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5047
Advantage
50
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-83725681-603
Fax
+86 755 28094224
Country
China
ProdList
4496
Advantage
50
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Beijing Comparison Pharmaceutical Technology Co., Ltd
Tel
010-010-52878169 15801002657
Email
sales@bjcomparison.com
Country
China
ProdList
4954
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4566
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18042
Advantage
56
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5219
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10276
Advantage
55
Shandong Boluoda Biological Technology Co., Ltd.
Tel
0531-58190570 15863796298
Email
2310993908@qq.com
Country
China
ProdList
1296
Advantage
58
Tianjin Anhao Biological Technology Co., Ltd.
Tel
Email
sales@ahpharmatech.com
Country
China
ProdList
5734
Advantage
55
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
Advantage
50
Shanghai Na Qian Chemical Technology Co. Ltd.
Tel
0373-7129549; 13598610367
Fax
QQ:2468833170
Email
2841375912@qq.com
Country
China
ProdList
2724
Advantage
52
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-66023220 0086-15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7850
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9923
Advantage
55
WG reagent
Tel
13391486464
Fax
QQ:14748090
Email
samwjf@163.com
Country
China
ProdList
3086
Advantage
55
Grader reagent
Tel
18221735425
Email
sales@xinpingchem.com
Country
China
ProdList
9942
Advantage
58
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
lucy@atkchemical.com
Country
China
ProdList
9204
Advantage
58
Shijiazhuang yaoBo Pharmaceutical Co., Ltd.
Tel
15633056635
Email
2880679888@qq.com
Country
China
ProdList
2916
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886750 13927877953
Fax
0751-2886750
Email
3005811397@qq.com
Country
China
ProdList
13320
Advantage
58
Shenzhen Sendi Biological Technology Co., Ltd.
Tel
18124570582 TEL：0755-23574479 2355327139
Fax
0755-23229476 QQ: 2355327139
Email
siliao02@yccreate.com
Country
China
ProdList
6116
Advantage
58
More
Less

View Lastest Price from 4'-(2-Methylpropyl)acetophenone manufacturers

Hebei Mojin Biotechnology Co., Ltd
Product
4'-(2-Methylpropyl)acetophenone 38861-78-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2024-10-30
Hebei Mojin Biotechnology Co.,Ltd
Product
4'-(2-Methylpropyl)acetophenone 38861-78-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-09-27
Hebei Weibang Biotechnology Co., Ltd
Product
4'-(2-Methylpropyl)acetophenone 38861-78-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2022-09-30

38861-78-8, 4'-(2-Methylpropyl)acetophenoneRelated Search:

Ibuprofen 1-Hydroxyibuprofen (S)-(+)-Ibuprofen 1-Oxo Ibuprofen Ibuprofen Ethyl Ester 2-[4-(2-Methylpropyl)phenyl] ethanol 6-isobutyl-3-methyl-2,3-dihydro-1H-inden-1-one 2-(4-Methylphenyl)propanoic acid (2RS)-2-(4-BUTYLPHENYL)PROPANOIC ACID rac 2-Hydroxy Ibuprofen 4-(2-Methylpropyl)benzeneethanol (R)-(-)-IBUPROFEN Ibuprofen EP Impurity I 3-(4-ISOBUTYL-PHENYL)-PROPIONIC ACID p-Isobutylstyrene rac-Ibuprofen amide rac a-Hydroxy Ibuprofen (2RS)-2-(4-FORMYLPHENYL)PROPANOIC ACID Ibuprofen Impurity E

  • Imp. E:1-(4-isobutylphenyl)ethanone
  • TIMTEC-BB SBB007668
  • P-ISO-BUTYLACETOPHENONE
  • IBUPROFEN IMPURITY E
  • IBUPROFEN IMP E
  • ISOBUTYL ACETOPHENONE
  • 4'-Isobutylacetophenone, 97+%
  • 4'-ISOBUTYLACETOPHENONE
  • 4-ISOBUTYLACETOPHENONE
  • 1-[4-(2-METHYLPROPYL)PHENYL]ETHANONE
  • 1-(4-ISOBUTYLPHENYL)ETHAN-1-ONE
  • 1-(4-ISOBUTYLPHENYL)ETHANONE
  • 1-[4-(2-methylpropyl)phenyl]-ethanon
  • 4-Isobutylacetaphenone
  • 1-[4-(2-methylpropyl)phenyl]ethan-1-one
  • 1-(4-(2-METHYLPROPYL)PHENYL)ETNANONE
  • 4'-(2-Methylpropyl)acetophenone
  • 4-lsobutylacetophenone
  • Acetophenone, 4-isobutyl-
  • Ethanone, 1-[4-(2-methylpropyl)phenyl]-
  • Nsc173015
  • p-Isobutylacetoph
  • Ibuprofen IMpurity-E(EP)
  • 4'-(2-Methylpropyl)a
  • 1-[4-(2-Methylprop-1-yl)phenyl]ethan-1-one, 1-(4-Isobutylphenyl)ethan-1-one
  • Ibuprofen Related CoMpound C, USP
  • 3 ampules) (4-isobutylacetophenone)
  • 4-ISOBUTYLACETOPHENONE(Ibuprofen Related Compound C)(Ibuprofen Impurity E)
  • 1Y1&1R DV1
  • Ibuprofen-4
  • Ibuprofen Related Compound C (0.2 mL/ampule
  • 1-[4-(2-Methylpropyl)phenyl]-1-ethanone
  • 1-Acetyl-4-isobutylbenzene
  • p-Acetylisobutylbenzene
  • Ibuprofen EP Impurity E
  • 4-IBAP
  • Ibuprofen USP Related Compound C
  • Ibuprofen EP Impurity E：Ibuprofen Impurity E
  • 4'-Isobutylacetophenone&gt
  • 4-Isobutylacetophenone（Ibuprofen Impurity）
  • Ibuprofen Impurity 5（Ibuprofen EP Impurity E）
  • Ibuprofen Impurity E/4-isobutylacetophenone
  • Ibuprofen EP Impurity E/ Ibuprofen Related Compound C
  • Ibuprofen USP Related Compound CQ: What is Ibuprofen USP Related Compound C Q: What is the CAS Number of Ibuprofen USP Related Compound C Q: What is the storage condition of Ibuprofen USP Related Compound C Q: What are the applications of Ibuprofen USP Related Compound C
  • Ibuprofen EP Impurit
  • 4'-Isobutylacetophenone, ≥ 96.0%
  • 4’-Isobutylacetophenone
  • 4'-(2-Methylpropyl)acetophenone
  • 38861-78-8
  • Aromatic Acetophenones & Derivatives (substituted)
  • Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Aromatics
  • Impurities
  • Intermediates & Fine Chemicals
  • Pharmaceuticals