2-(4-Methylphenyl)propanoic acid

Product Name: 2-(4-Methylphenyl)propanoic acid
CAS No.: 938-94-3
Chemical Name: 2-(4-Methylphenyl)propanoic acid
Synonyms: 2-p-Tolylpropanoic acid;2-(P-TOLYL)PROPIONIC ACID;(2RS)-2-(4-METHYLPHENYL)PROPANOIC ACID;Ibuprofen-3;2-(4-MethyL;5932B+5242:5246;IBUPROFEN IMP D;2-(4-Methylphenyl)pr;IBUPROFEN IMPURITY D;Ibuprofen EP Impurity D
CBNumber: CB1333307
Molecular Formula: C10H12O2
Formula Weight: 164.2
MOL File: 938-94-3.mol

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2-(4-Methylphenyl)propanoic acid Property

Melting point:: 37-42 °C(lit.)
Boiling point:: 231.67°C (rough estimate)
Density: 1.0041 (rough estimate)
refractive index: 1.518-1.52
Flash point:: >230 °F
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 4.44±0.10(Predicted)
color: White to Off-White
BRN: 2251315
InChI: InChI=1S/C10H12O2/c1-7-3-5-9(6-4-7)8(2)10(11)12/h3-6,8H,1-2H3,(H,11,12)
InChIKey: KDYOFXPLHVSIHS-UHFFFAOYSA-N
SMILES: C(C1C=CC(C)=CC=1)(C)C(=O)O
CAS DataBase Reference: 938-94-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29163990
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR3321
Product name: (2RS)-2-(4-methylphenyl)propanoic acid
Purity: certified reference material, pharmaceutical secondary standard
Packaging: 50MG
Price: $706.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: 522449
Product name: α,4-Dimethylphenylacetic acid
Purity: 97%
Packaging: 5g
Price: $151
Updated: 2023/06/20

TCI Chemical

Product number: M1352
Product name: (±)-2-(p-Tolyl)propanoic Acid
Purity: min. 95.0 %
Packaging: 25G
Price: $68
Updated: 2025/07/31

TRC

Product number: T536780
Product name: 2-(p-Tolyl)propionicAcid
Packaging: 1g
Price: $70
Updated: 2021/12/16

TRC

Product number: T536780
Product name: 2-(p-Tolyl)propionicAcid
Packaging: 25g
Price: $300
Updated: 2021/12/16

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2-(4-Methylphenyl)propanoic acid Chemical Properties,Usage,Production

Chemical Properties

clear yellow liquid after melting

Uses

2-(p-Tolyl)propionic acid (Ibuprofen EP Impurity D) is an impurity of Ibuprofen (I140000). Ibuprofen impurity D.

Uses

2-(p-Tolyl)propionic acid is an impurity of Ibuprofen (I140000). Ibuprofen impurity D.

Synthesis Reference(s)

Synthesis, p. 231, 1984 DOI: 10.1055/s-1984-30784
Tetrahedron Letters, 36, p. 5641, 1995 DOI: 10.1016/0040-4039(95)01035-G

General Description

α,4-Dimethylphenylacetic acid is also referred to as 2-(4-methylphenyl)propanoic acid. It is an alkaline decomposition product of azalomycin-B, a macrolide antibiotic produced by Streptomyces hygroscopicus var. azalomyceticus. The reaction of pinonic acid with bromine in water affords 2-(4-methylphenyl)propanoic acid.

2-(4-Methylphenyl)propanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(4-Methylphenyl)propanoic acid Suppliers

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View Lastest Price from 2-(4-Methylphenyl)propanoic acid manufacturers

Weifang Integratechem Co., Ltd.

Product: 2-(4-Methylphenyl)propanoic acid(MPPA) 938-94-3
Price: US $0.00/kg
Min. Order: 800kg
Purity: 99%
Supply Ability: 50 ton per month
Release date: 2025-08-25

Moxin Chemicals

Product: Ibuprofen EP Impurity D 938-94-3
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 95%+
Supply Ability: 100000
Release date: 2025-03-19

Henan Fengda Chemical Co., Ltd

Product: 2-(4-Methylphenyl)propanoic acid 938-94-3
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-16

938-94-3, 2-(4-Methylphenyl)propanoic acidRelated Search:

Propionic acid METHYLSTYRENE Silicone oil (high temperature) 2,3-Dibromopropionic acid Chlorodimethylphenylsilane Propionic anhydride 2-Chloropropionic acid DL-Phenylalanine (S)-(+)-2-Phenylpropionic acid 1-Methyl-4-(methylsulfonyl)-benzene 2,2-Bis(hydroxymethyl)propionic acid IBUPROFEN IMP. D (EP): 2-(4-METHYLPHENYL)PROPANOIC ACID MM(CRM STANDARD) (S)-(+)-Ibuprofen Z-AIB-OH (R)-(-)-IBUPROFEN 1-Hydroxyibuprofen 1-Oxo Ibuprofen Ibuprofen Ethyl Ester

2-(p-Tolyl)propionic acidalpha,4-Dimethylphenylacetic acid

2-(4-Methylphenyl)pr

2-(p-Tolyl)propionic acid, 98% 5GR

α-(p-Tolyl)propionic Acid

α,4-DiMethylbenzeneacetic Acid

Ibuprofen IMpurity-D -(EP)

Ibuprofen EP Impurity D

5932B+5242:5246

2-(4-METHYLPHENYL)PROPA

Ibuprofen-3

2-(p-Tolyl)proplonic acid

Ibuprofen EP Impurity D (2-(p-Tolyl)propionic Acid)

(2S)-2-(4-methylphenyl)propanoate

IBUPROFEN IMP D

IBUPROFEN IMPURITY D

4-METHYL-2-PHENYLPROPIONIC ACID

alpha,4-Dimethylphenylacetic acid 97%

(2R)-2-(4-Methylphenyl)propanoic acid

ALPHA,4-DIMETHYLPHENYLACETIC ACID

2-(4-METHYLPHENYL)PROPANOIC ACID

2-(4-METHYLPHENYL)PROPIONIC ACID

2-(P-TOLYL)PROPIONIC ACID

(2RS)-2-(4-METHYLPHENYL)PROPANOIC ACID

2-(p-Methylphenyl)propionic acid

a,4-Dimethylbenzeneacetic acid

2-(p-Tolyl)propionic acid,98%

2-p-Tolylpropanoic acid

α,4-dimethylphenylacetic acid

p-Methylhydratropic acid.

2-(4-tolyl)propanoic acid

2-(4-Tolyl)propionic acid

Methylphenylpropinoic acid

2-p-Tolylpropanoic acid / 2-(4-Tolyl)propionic acid

Ibuprofen EP Impurity D：Ibuprofen Impurity D

(2RS)-2-(4-Methylphenyl)propanoic A

2-(4-MethyL

Benzeneacetic acid, α,4-dimethyl-

Ibuprofen Impurity 4（Ibuprofen EP Impurity D）

p-Methyl isopropionic acid　

Ibuprofen Impurity DQ: What is Ibuprofen Impurity D Q: What is the CAS Number of Ibuprofen Impurity D Q: What is the storage condition of Ibuprofen Impurity D Q: What are the applications of Ibuprofen Impurity D

2-(4-Methylphenyl)propanoicaci

(2<i>RS</i>)-2-(4-methylphenyl)propanoic acid

2- (p-toluene) propionic acid

2-(4-Methylphenyl)propanoic acid(MPPA)

938-94-3

CH3C6H4CHCH3CO2H

CARBOXYLIC ACID

Building Blocks

Carbonyl Compounds

Carboxylic Acids

C10

Organic Building Blocks

Aromatic Propionic Acids

Carboxylic Acids

Phenyls & Phenyl-Het

Carboxylic Acids

Phenyls & Phenyl-Het

Intermediates