Description References
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DL-Phenylalanine

Description References
Product Name
DL-Phenylalanine
CAS No.
150-30-1
Chemical Name
DL-Phenylalanine
Synonyms
3-AMINO-3-PHENYLPROPANOIC ACID;DL-3-PHENYLALANINE;H-DL-PHE-OH;DL-PHENYALANINE;3 AMINO-PHENYLPROPIONIC ACID;D,L-PHE;DLPA 375;NSC 9959;FEMA 3726;DL-Phenylalani
CBNumber
CB4140195
Molecular Formula
C9H11NO2
Formula Weight
165.19
MOL File
150-30-1.mol
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DL-Phenylalanine Property

Melting point:
266-267 °C (dec.) (lit.)
Boiling point:
293.03°C (rough estimate)
Density 
1.1603 (rough estimate)
refractive index 
1.5200 (estimate)
FEMA 
3726 | D,L-PHENYLALANINE
storage temp. 
Store at RT.
solubility 
Water (Sparingly, Sonicated)
form 
Powder
pka
pK1 2.58; pK2 9.24(at 25℃)
color 
White
Odor
odorless
Odor Type
odorless
Water Solubility 
14.11 g/L (25 ºC)
Merck 
14,7271
JECFA Number
1432
BRN 
1910407
Stability:
Stable. Incompatible with strong oxidizing agents.
LogP
0.24
CAS DataBase Reference
150-30-1(CAS DataBase Reference)
NIST Chemistry Reference
L-Phenylalanine(150-30-1)
EPA Substance Registry System
Phenylalanine (150-30-1)
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Safety

Hazard Codes 
Xi,C
Risk Statements 
36/37/38-34
Safety Statements 
37/39-24/25-45-36/37/39-27-26
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29224995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
147966
Product name
DL-Phenylalanine
Purity
ReagentPlus , 99%
Packaging
25g
Price
$37.4
Updated
2024/03/01
Sigma-Aldrich
Product number
147966
Product name
DL-Phenylalanine
Purity
ReagentPlus , 99%
Packaging
100g
Price
$73
Updated
2024/03/01
TCI Chemical
Product number
P0136
Product name
DL-Phenylalanine
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$33
Updated
2024/03/01
TCI Chemical
Product number
P0136
Product name
DL-Phenylalanine
Purity
>98.0%(HPLC)(T)
Packaging
250g
Price
$128
Updated
2021/12/16
Alfa Aesar
Product number
A10132
Product name
DL-Phenylalanine, 99%
Packaging
25g
Price
$25.1
Updated
2024/03/01
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DL-Phenylalanine Chemical Properties,Usage,Production

Description

As an essential amino acid, phenylalanine is necessary for the production of tyrosine in human body, which cannot be synthesized from more basic substances in humans and other animals, meaning that it is obtained only by ingestion of phenylalanine or phenylalanine- containing proteins, which is particularly rich in eggs, chicken, liver, beef, breast milk of mammals, and soybeans, etc. There are three forms of phenylalanine: L-phenylalanine, the natural form found in protein-rich foods, D-phenylalanine, the synthetic mirror image and DL-Phenylalanine (DLPA), the mixture of both forms made in the laboratory that can maximize benefits. DLPA is manufactured for medical, feed, and nutritional applications, which can be used to produce food and drink products. It is marketed as a nutritional supplement due to its reputed analgesic and antidepressant effects. Besides, it can be applied for depression, attention deficit-hyperactivity disorder (ADHD), Parkinson's disease, chronic pain, osteoarthritis, rheumatoid arthritis, alcohol withdrawal symptoms, and a skin disease called vitiligo.

References

https://en.wikipedia.org/wiki/Phenylalanine
http://www.livestrong.com/article/501701-what-are-the-benefits-of- dl-phenylalanine/
http://www.webmd.com/vitamins-supplements/ingredientmono-653- phenylalanine.aspx? activeingredientid=653&activeingredientname=phenylalanine

Chemical Properties

White crystalline powder

Chemical Properties

DL-Phenylalanine has a sweet taste. It is an essential amino acid that plays a key role in the biosynthesis of other amino acids and some neurotransmitters.

Occurrence

Phenylalanine is the most commonly found aromatic amino acid in proteins and enzymes with a molar ratio of 3.5% compared to the other amino acids, about double the amount of any other aromatic amino acid. Reported found in white bread, macaroni, egg noodles, corn flakes, corn grits, oatmeal, wheat bran, wheat flakes, shredded wheat, barley, brown rice, rye flour, whole grain wheat flour, buttermilk, blue cheese, cheddar cheese, cottage cheese, cream cheese, parmesan cheese, bacon, cured ham, frankfurters, pork sausage, canned red kidney beans, canned sweet corn, canned peas, canned lima beans, canned potatoes, canned asparagus, canned snap beans, canned beets, beef, lamb, fresh ham, veal round, beef liver, chicken, chicken liver, turkey and other natural sources.

Uses

DL-Phenylalanine is used to?relieve cases of minor depression?and other mood issues as well as and physical discomforts and pain. It is also used in acupuncture?anesthesia, alcohol withdrawal.

Uses

DL-Phenylalanine may be used in the synthesis of ternary piroxicam (Pir; 4-hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) complexes of Fe(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II).

Uses

Component of the artificial sweetner aspartame, q.v.; nutrient.

Preparation

By microbial bioengineered process.

Definition

ChEBI: An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group.

General Description

Phenylalanine is an amino acid. It participates in the preparation of ternary piroxicam complexes of Fe(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II). Characterization of these complexes by elemental analyses, molar conductance, IR, UV-Vis, magnetic moment, diffuse reflectance and X-ray powder diffraction methods has been conducted. Crystalline DL-phenylalanine was prepared by its reduction in silica gel by solubility method.

Purification Methods

dl-Phenylalanine crystallises from H2O or H2O/EtOH in large plates and is dried under vacuum over P2O5. S-Phenylalanine ethyl ester hydrochloride has m 156-158o and [ ] D -7.8o (c 2, H2O) after crystallisation from EtOH/Et2O [Billimoria & Cook J Chem Soc 2328 1949, Beilstein 14 IV 1556]. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2156-2175 1961, Beilstein 14 III 1229, 14 IV 1553.]

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DL-Phenylalanine Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
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View Lastest Price from DL-Phenylalanine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
DL-Phenylalanine 150-30-1
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98.5%-101.5%; FCC-V
Supply Ability
20 TONS
Release date
2021-06-05
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
DL-Phenylalanine 150-30-1
Price
US $99.00-66.00/kg
Min. Order
0.001kg
Purity
99%
Supply Ability
5000
Release date
2024-08-09
Hebei Weibang Biotechnology Co., Ltd
Product
DL-Phenylalanine 150-30-1
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-24

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