N-(tert-Butoxycarbonyl)-L-phenylalanine

Product Name: N-(tert-Butoxycarbonyl)-L-phenylalanine
CAS No.: 13734-34-4
Chemical Name: N-(tert-Butoxycarbonyl)-L-phenylalanine
Synonyms: BOC-PHE-OH;BOC-PHE;BOC-L-PHE-OH;BOC-L-PHE;BOC-L-PHENYLALANINE;N-BOC-L-PHENYLALANINE;BOC-PHENYLALANINE;L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-;BOC-ph-OH;BOC Phenly Alanine
CBNumber: CB4781305
Molecular Formula: C14H19NO4
Formula Weight: 265.3
MOL File: 13734-34-4.mol

More

Less

N-(tert-Butoxycarbonyl)-L-phenylalanine Property

Melting point:: 85-87 °C(lit.)
Boiling point:: 408.52°C (rough estimate)
Density: 1.1356 (rough estimate)
refractive index: 24.5 ° (C=1, EtOH)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Soluble in methanol, dichloromethane, dimethylformamide and N-methyl-2-pyrrolidone.
pka: 3.88±0.10(Predicted)
form: Fine Crystalline Powder
color: White
optical activity: [α]20/D +25±1°, c = 1% in ethanol
BRN: 2219729
InChI: InChI=1S/C14H19NO4/c1-14(2,3)19-13(18)15-11(12(16)17)9-10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,15,18)(H,16,17)/t11-/m0/s1
InChIKey: ZYJPUMXJBDHSIF-NSHDSACASA-N
SMILES: C(O)(=O)[C@H](CC1=CC=CC=C1)NC(OC(C)(C)C)=O
CAS DataBase Reference: 13734-34-4(CAS DataBase Reference)
EPA Substance Registry System: L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- (13734-34-4)

More

Less

Safety

Hazard Codes: Xn,Xi
Risk Statements: 36-22-36/37/38-20/21/22
Safety Statements: 39-26-36-24/25
WGK Germany: 3
TSCA: Yes
HS Code: 29242990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.53006
Product name: Boc-Phe-OH
Purity: Novabiochem?
Packaging: 25g
Price: $57.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.53006
Product name: Boc-Phe-OH
Purity: Novabiochem?
Packaging: 100g
Price: $66
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.53006
Product name: Boc-Phe-OH
Purity: Novabiochem<SUP>®</SUP>
Packaging: 1 kg
Price: $1290
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.53006
Product name: Boc-Phe-OH
Purity: Novabiochem<SUP>®</SUP>
Packaging: 1 kg
Price: $1290
Updated: 2025/07/31

Sigma-Aldrich

Product number: 15480
Product name: Boc-Phe-OH
Purity: ≥99.0% (T)
Packaging: 5g
Price: $40.4
Updated: 2025/07/31

More

Less

N-(tert-Butoxycarbonyl)-L-phenylalanine Chemical Properties,Usage,Production

Chemical Properties

N-(tert-Butoxycarbonyl)-L-phenylalanine is white fine crystalline powder

Uses

N-Boc-L-phenylalanine is a derivative of Phenylalanine used in enantioselective hydrolysis of amino acid esters.

Uses

N-(tert-Butoxycarbonyl)-L-phenylalanine is used in enantioselective hydrolysis of amino acid esters. Acts as an inhibitor of gastric acid secretion.

Preparation

Sodium hydroxide (4.4 g, 0.11 mol) was placed in a flask, and dissolved in water (110 mL). Phenylalanine (16.5 g, 0.1 mol) was added, the suspension was stirred until a solution was obtained, and then tert-butanol (75 mL) was added. Boc2O (22.3 g, 0.12 mol) was then added with stirring over a period of 1 h, keeping the mixture near 0 ℃. A white precipitate was produced, and at the end of the addition the pH had dropped to 7.5–8.5. The mixture was then carefully acidified by the slow, continuous addition of saturated citric acid to give the product N-tert-butoxycarbonyl-L-phenylalanine (21.5 g, 81%); mp 85℃; [a]21D = t25:5 (c = 1, ethanol).

reaction suitability

reaction type: Boc solid-phase peptide synthesis
reaction type: C-H Activation
reagent type: ligand
reaction type: Peptide Synthesis

N-(tert-Butoxycarbonyl)-L-phenylalanine Preparation Products And Raw materials

Raw materials

L-Phenylalanine 1,4-Dioxane

Preparation Products

More

Less

N-(tert-Butoxycarbonyl)-L-phenylalanine Suppliers

Americas 1 Belgium 1 Canada 3 China 479 Europe 3 France 3 Germany 9 Hungary 1 India 46 Japan 11 Slovakia 1 South Korea 1 Switzerland 8 United Kingdom 18 United States 78 Global 663

Zhejiang Aobang Pharmaceutical & Chemical Co. LTD

Tel: 13676682222 13676682222;
Email: 877870302@qq.com
Country: China
ProdList: 28
Advantage: 58

Shanghai Jifeng Biotechnology Co., Ltd.

Tel: 021-61263377 15023907684
Fax: 021-61263399
Email: 15800684150@163.com
Country: China
ProdList: 8131
Advantage: 58

Beijing Bainiannuan Sci.&Tec. Co., Ltd

Tel: 13240490036
Fax: +86-10-51765262
Email: marymeng@bdnchem.com
Country: China
ProdList: 34
Advantage: 58

GenChem & GenPharm (Changzhou) Co., Ltd.

Tel: 0519-85720003 18861157602
Fax: 0519-85720007
Email: 410649415@qq.com
Country: China
ProdList: 111
Advantage: 58

Jinan Dexinjia Bio&Tech Co., Ltd

Tel: 0531-82375886 15553111391
Fax: 0531-82375893
Email: 3663651392@qq.com
Country: China
ProdList: 1615
Advantage: 58

Nanjing Ally Chemical S&T Co., Ltd.

Tel: 025-025-58367986 18913956109
Fax: QQ:3209878052
Email: amy.xiang@ally-chem.com
Country: China
ProdList: 561
Advantage: 58

Shanxi Nuocheng Biotechnology Co., Ltd

Tel: 17835231871
Email: 572710841@qq.com
Country: China
ProdList: 331
Advantage: 58

Nanjing Yihua Biotechnology Co., Ltd

Tel: 13429882898
Email: 1096323105@qq.com
Country: China
ProdList: 290
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

PharmaBlock Sciences (Nanjing),Inc.

Tel: 025-86918202 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 5000
Advantage: 55

More

Less

View Lastest Price from N-(tert-Butoxycarbonyl)-L-phenylalanine manufacturers

Sichuan Zhuoyu Yantang Technology Co., Ltd.

Product: N-(tert-Butoxycarbonyl)-L-phenylalanine 13734-34-4
Price: US $100.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 300tons
Release date: 2025-09-17

Shaanxi Xianhe Biotech Co., Ltd

Product: N-(tert-Butoxycarbonyl)-L-phenylalanine 13734-34-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 0.99
Supply Ability: 1000KG
Release date: 2025-04-24

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Boc-Phe-OH 13734-34-4
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1000kgs
Release date: 2021-09-23

13734-34-4, N-(tert-Butoxycarbonyl)-L-phenylalanineRelated Search:

L-Alanine BOC-Glycine Boc-D-Glutamine BOC-MET-ONP BOC-GLU(OME)-OH Boc-L-Pyroglutamic acid methyl ester Boc-L-glutamic acid γ-allyl ester BOC-TYR(ET)-OH BOC-PHE-OSU 4-Amino-N-(tert-butoxycarbonyl)-L-phenylalanine BOC-4-NITRO-L-PHENYLALANINE BOC-L-4-Chlorophe Boc-N-methyl-L-phenylalanine N-tert-Butoxycarbonyl-L-phenylalanine amide BOC-D-Phenylalanine N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANINE ACID HYDRAZIDE N-tert-Butoxycarbonyl-DL-phenylalanine BOC-4-IODO-L-PHENYLALANINE

n-[(1,1-dimethylethoxy)carbonyl]-l-phenylalanin

L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-

N-(tert-Butoxycarbonyl)-L-phenylalanine ,98.5%

Boc-L-phenylalanine ,98%

(2S)-2-(tert-Butoxycarbonylamino)-3-phenylpropionic acid

(S)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoic acid

N-(tert-Butyloxycarbonyl)-L-phenylalanine

N-(tert-butoxycarbonyl)-L-phenylalaninal

Boc-L-phenylalanine ,98.5%

2-BOC-AMINO-3-PHENYL-PROPIONIC ACID

Boc-L-phenylalanine,N-(tert-Butoxycarbonyl)-L-phenylalanine

L-PHENYLALANINE-N-T-BOC

(S)-N-(tert-Butoxycarbonyl)phenylalanine

tert-Butoxycarbonyl-L-phenylalanine

N-Boc-L-phenylalanine Boc-Phe-OH

(2S)-2-{[(tert-butoxy)carbonyl]aMino}-3-phenylpropanoic acid

Boc-Phe-OH >=99.0% (T)

N-(tert-Butoxycarbonyl)-L-phenylalanine SynonyMs N-[(1,1-DiMethylethoxy)carbonyl]-L-phenylalanine

Boc-L-phenylalanine≥ 99% (HPLC)

Tert-Butoxycarbonyl L-Phenylalanine (BOC-L Phenylalanine)

BOC-L-Phenylalanine, 99+%

BOC-L-Phenylalanine(Boc-Phe-OH)

N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANINE(BOC-L-PHE-OH)

2-TERT-BUTOXYCARBONYLAMINO-3-PHENYL-PROPIONIC ACID

N-Butoxycarbonyl-L-phenylalanine

N-T-BOC-L-PHENYLALANINE FREE ACID

N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANINE, 99+%

BOC-PHE-OH

BOC-PHENYLALANINE

BOC-PHE

BOC-L-PHE

BOC-L-PHENYLALANINE

BOC-L-PHENYLALANINE-OH

BOC-L-PHE-OH

Boc-Phe-OH (Boc-L-Phenylalanine)

N-ALPHA-T-BUTYLOXYCARBONYL-L-PHENYLALANINE

(2R)-3-phenyl-2-(tert-butoxycarbonylamino)propanoic acid

BOC Phenly Alanine

BOC-L-PHENYLALANINE extrapure

N-(tert-Butoxycarbonyl)-L-phenylalanine, Boc-L-phenylalanine

N-TERT-BUTYLOXYCARBONYL-DL-PHENYLALANINE

N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANINE

N-T-BOC-L-PHENYLALANINE

N-T-BUTOXYCARBONYL-L-PHENYLALANINE

N-[(1,1-Dimethylethoxy)carbonyl]-L-phenylalanine

N-BOC-L-PHENYLALANINE

N-ALPHA-TERT-BUTYLOXYCARBONYL-L-PHENYLALANINE

N-ALPHA-T-BUTOXYCARBONYL-L-PHENYLALANINE

N-ALPHA-T-BOC-L-PHENYLALANINE

T-BUTYLOXYCARBONYL-L-PHENYLALANINE

TBOC-L-PHENYLALANINE

(S)-2-TERT-BUTOXYCARBONYLAMINO-3-PHENYL-PROPIONIC ACID

RARECHEM AL BE 0755

N-Boc-L-phenylalanine,99%e.e.

(Tert-Butoxy)Carbonyl Phe-OH

(2S-2-[(2-MethylpropaN-2-Yloxycarbonylamino]-3-Phenylpropanoic Acid

N-(tert-Butoxycarbonyl)-L-phenylalanine &gt

BOC-ph-OH