N-(tert-Butoxycarbonyl)-L-phenylalanine
- Product Name
- N-(tert-Butoxycarbonyl)-L-phenylalanine
- CAS No.
- 13734-34-4
- Chemical Name
- N-(tert-Butoxycarbonyl)-L-phenylalanine
- Synonyms
- BOC-PHE-OH;BOC-PHE;BOC-L-PHE-OH;BOC-L-PHE;BOC-L-PHENYLALANINE;N-BOC-L-PHENYLALANINE;BOC-PHENYLALANINE;L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-;BOC-ph-OH;BOC Phenly Alanine
- CBNumber
- CB4781305
- Molecular Formula
- C14H19NO4
- Formula Weight
- 265.3
- MOL File
- 13734-34-4.mol
N-(tert-Butoxycarbonyl)-L-phenylalanine Property
- Melting point:
- 85-87 °C(lit.)
- Boiling point:
- 408.52°C (rough estimate)
- Density
- 1.1356 (rough estimate)
- refractive index
- 24.5 ° (C=1, EtOH)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Soluble in methanol, dichloromethane, dimethylformamide and N-methyl-2-pyrrolidone.
- form
- Fine Crystalline Powder
- pka
- 3.88±0.10(Predicted)
- color
- White
- optical activity
- [α]20/D +25±1°, c = 1% in ethanol
- BRN
- 2219729
- CAS DataBase Reference
- 13734-34-4(CAS DataBase Reference)
- EPA Substance Registry System
- L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- (13734-34-4)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 36-22-36/37/38-20/21/22
- Safety Statements
- 39-26-36-24/25
- WGK Germany
- 3
- TSCA
- Yes
- HS Code
- 29242990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 8.53006
- Product name
- Boc-Phe-OH
- Purity
- Novabiochem?
- Packaging
- 25g
- Price
- $56.1
- Updated
- 2024/03/01
- Product number
- 15480
- Product name
- Boc-Phe-OH
- Purity
- ≥99.0% (T)
- Packaging
- 5g
- Price
- $23.52
- Updated
- 2024/03/01
- Product number
- 8.53006
- Product name
- Boc-Phe-OH
- Purity
- Novabiochem?
- Packaging
- 100g
- Price
- $129
- Updated
- 2024/03/01
- Product number
- 15480
- Product name
- Boc-Phe-OH
- Purity
- ≥99.0% (T)
- Packaging
- 25g
- Price
- $107
- Updated
- 2024/03/01
- Product number
- B1332
- Product name
- N-(tert-Butoxycarbonyl)-L-phenylalanine
- Purity
- >99.0%(T)
- Packaging
- 5g
- Price
- $16
- Updated
- 2024/03/01
N-(tert-Butoxycarbonyl)-L-phenylalanine Chemical Properties,Usage,Production
Chemical Properties
N-(tert-Butoxycarbonyl)-L-phenylalanine is white fine crystalline powder
Uses
N-Boc-L-phenylalanine is a derivative of Phenylalanine used in enantioselective hydrolysis of amino acid esters.
Uses
N-(tert-Butoxycarbonyl)-L-phenylalanine is used in enantioselective hydrolysis of amino acid esters. Acts as an inhibitor of gastric acid secretion.
Preparation
Sodium hydroxide (4.4 g, 0.11 mol) was placed in a flask, and dissolved in water (110 mL). Phenylalanine (16.5 g, 0.1 mol) was added, the suspension was stirred until a solution was obtained, and then tert-butanol (75 mL) was added. Boc2O (22.3 g, 0.12 mol) was then added with stirring over a period of 1 h, keeping the mixture near 0 ℃. A white precipitate was produced, and at the end of the addition the pH had dropped to 7.5–8.5. The mixture was then carefully acidified by the slow, continuous addition of saturated citric acid to give the product N-tert-butoxycarbonyl-L-phenylalanine (21.5 g, 81%); mp 85℃; [a]21D = t25:5 (c = 1, ethanol).
N-(tert-Butoxycarbonyl)-L-phenylalanine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-(tert-Butoxycarbonyl)-L-phenylalanine manufacturers
- Product
- Boc-Phe-OH 13734-34-4
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-12-02
- Product
- Boc-Phe-OH 13734-34-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2023-09-21
- Product
- Boc-Phe-OH 13734-34-4
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1000kgs
- Release date
- 2021-09-23