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N-(tert-Butoxycarbonyl)-L-phenylalanine

Product Name
N-(tert-Butoxycarbonyl)-L-phenylalanine
CAS No.
13734-34-4
Chemical Name
N-(tert-Butoxycarbonyl)-L-phenylalanine
Synonyms
BOC-PHE-OH;BOC-PHE;BOC-L-PHE-OH;BOC-L-PHE;BOC-L-PHENYLALANINE;N-BOC-L-PHENYLALANINE;BOC-PHENYLALANINE;L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-;BOC-ph-OH;BOC Phenly Alanine
CBNumber
CB4781305
Molecular Formula
C14H19NO4
Formula Weight
265.3
MOL File
13734-34-4.mol
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N-(tert-Butoxycarbonyl)-L-phenylalanine Property

Melting point:
85-87 °C(lit.)
Boiling point:
408.52°C (rough estimate)
Density 
1.1356 (rough estimate)
refractive index 
24.5 ° (C=1, EtOH)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in methanol, dichloromethane, dimethylformamide and N-methyl-2-pyrrolidone.
form 
Fine Crystalline Powder
pka
3.88±0.10(Predicted)
color 
White
optical activity
[α]20/D +25±1°, c = 1% in ethanol
BRN 
2219729
CAS DataBase Reference
13734-34-4(CAS DataBase Reference)
EPA Substance Registry System
L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- (13734-34-4)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36-22-36/37/38-20/21/22
Safety Statements 
39-26-36-24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29242990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.53006
Product name
Boc-Phe-OH
Purity
Novabiochem?
Packaging
25g
Price
$56.1
Updated
2024/03/01
Sigma-Aldrich
Product number
8.53006
Product name
Boc-Phe-OH
Purity
Novabiochem?
Packaging
100g
Price
$129
Updated
2024/03/01
Sigma-Aldrich
Product number
15480
Product name
Boc-Phe-OH
Purity
≥99.0% (T)
Packaging
5g
Price
$23.52
Updated
2024/03/01
Sigma-Aldrich
Product number
15480
Product name
Boc-Phe-OH
Purity
≥99.0% (T)
Packaging
25g
Price
$107
Updated
2024/03/01
TCI Chemical
Product number
B1332
Product name
N-(tert-Butoxycarbonyl)-L-phenylalanine
Purity
>99.0%(T)
Packaging
5g
Price
$16
Updated
2024/03/01
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N-(tert-Butoxycarbonyl)-L-phenylalanine Chemical Properties,Usage,Production

Chemical Properties

N-(tert-Butoxycarbonyl)-L-phenylalanine is white fine crystalline powder

Uses

N-Boc-L-phenylalanine is a derivative of Phenylalanine used in enantioselective hydrolysis of amino acid esters.

Uses

N-(tert-Butoxycarbonyl)-L-phenylalanine is used in enantioselective hydrolysis of amino acid esters. Acts as an inhibitor of gastric acid secretion.

Preparation

Sodium hydroxide (4.4 g, 0.11 mol) was placed in a flask, and dissolved in water (110 mL). Phenylalanine (16.5 g, 0.1 mol) was added, the suspension was stirred until a solution was obtained, and then tert-butanol (75 mL) was added. Boc2O (22.3 g, 0.12 mol) was then added with stirring over a period of 1 h, keeping the mixture near 0 ℃. A white precipitate was produced, and at the end of the addition the pH had dropped to 7.5–8.5. The mixture was then carefully acidified by the slow, continuous addition of saturated citric acid to give the product N-tert-butoxycarbonyl-L-phenylalanine (21.5 g, 81%); mp 85℃; [a]21D = t25:5 (c = 1, ethanol).

N-(tert-Butoxycarbonyl)-L-phenylalanine Preparation Products And Raw materials

Raw materials

L-Phenylalanine 1,4-Dioxane

Preparation Products

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N-(tert-Butoxycarbonyl)-L-phenylalanine Suppliers

Americas 1 Belgium 1 Canada 3 China 439 Europe 3 France 3 Germany 9 Hungary 1 India 45 Japan 11 Slovakia 1 South Korea 1 Switzerland 8 United Kingdom 18 United States 79 Global 623
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23662
Advantage
75
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View Lastest Price from N-(tert-Butoxycarbonyl)-L-phenylalanine manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Boc-Phe-OH 13734-34-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2023-09-21
Henan Fengda Chemical Co., Ltd
Product
Boc-L-phenylalanine 13734-34-4
Price
US $5.00-0.50/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-13
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Boc-Phe-OH 13734-34-4
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kgs
Release date
2021-09-23

13734-34-4, N-(tert-Butoxycarbonyl)-L-phenylalanineRelated Search:

L-Alanine BOC-Glycine Boc-D-Glutamine BOC-MET-ONP BOC-GLU(OME)-OH Boc-L-Pyroglutamic acid methyl ester Boc-L-glutamic acid γ-allyl ester BOC-TYR(ET)-OH BOC-4-IODO-L-PHENYLALANINE BOC-PHE-OSU 4-Amino-N-(tert-butoxycarbonyl)-L-phenylalanine BOC-4-NITRO-L-PHENYLALANINE BOC-L-4-Chlorophe Boc-N-methyl-L-phenylalanine N-tert-Butoxycarbonyl-L-phenylalanine amide BOC-D-Phenylalanine N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANINE ACID HYDRAZIDE N-tert-Butoxycarbonyl-DL-phenylalanine

  • n-[(1,1-dimethylethoxy)carbonyl]-l-phenylalanin
  • L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-
  • N-(tert-Butoxycarbonyl)-L-phenylalanine ,98.5%
  • Boc-L-phenylalanine ,98%
  • (2S)-2-(tert-Butoxycarbonylamino)-3-phenylpropionic acid
  • (S)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoic acid
  • N-(tert-Butyloxycarbonyl)-L-phenylalanine
  • N-(tert-butoxycarbonyl)-L-phenylalaninal
  • Boc-L-phenylalanine ,98.5%
  • 2-BOC-AMINO-3-PHENYL-PROPIONIC ACID
  • Boc-L-phenylalanine,N-(tert-Butoxycarbonyl)-L-phenylalanine
  • L-PHENYLALANINE-N-T-BOC
  • (S)-N-(tert-Butoxycarbonyl)phenylalanine
  • tert-Butoxycarbonyl-L-phenylalanine
  • N-Boc-L-phenylalanine Boc-Phe-OH
  • (2S)-2-{[(tert-butoxy)carbonyl]aMino}-3-phenylpropanoic acid
  • Boc-Phe-OH >=99.0% (T)
  • N-(tert-Butoxycarbonyl)-L-phenylalanine SynonyMs N-[(1,1-DiMethylethoxy)carbonyl]-L-phenylalanine
  • Boc-L-phenylalanine≥ 99% (HPLC)
  • Tert-Butoxycarbonyl L-Phenylalanine (BOC-L Phenylalanine)
  • BOC-L-Phenylalanine, 99+%
  • BOC-L-Phenylalanine(Boc-Phe-OH)
  • N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANINE(BOC-L-PHE-OH)
  • 2-TERT-BUTOXYCARBONYLAMINO-3-PHENYL-PROPIONIC ACID
  • N-Butoxycarbonyl-L-phenylalanine
  • N-T-BOC-L-PHENYLALANINE FREE ACID
  • N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANINE, 99+%
  • BOC-PHE-OH
  • BOC-PHENYLALANINE
  • BOC-PHE
  • BOC-L-PHE
  • BOC-L-PHENYLALANINE
  • BOC-L-PHENYLALANINE-OH
  • BOC-L-PHE-OH
  • Boc-Phe-OH (Boc-L-Phenylalanine)
  • N-ALPHA-T-BUTYLOXYCARBONYL-L-PHENYLALANINE
  • (2R)-3-phenyl-2-(tert-butoxycarbonylamino)propanoic acid
  • BOC Phenly Alanine
  • BOC-L-PHENYLALANINE extrapure
  • N-(tert-Butoxycarbonyl)-L-phenylalanine, Boc-L-phenylalanine
  • N-TERT-BUTYLOXYCARBONYL-DL-PHENYLALANINE
  • N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANINE
  • N-T-BOC-L-PHENYLALANINE
  • N-T-BUTOXYCARBONYL-L-PHENYLALANINE
  • N-[(1,1-Dimethylethoxy)carbonyl]-L-phenylalanine
  • N-BOC-L-PHENYLALANINE
  • N-ALPHA-TERT-BUTYLOXYCARBONYL-L-PHENYLALANINE
  • N-ALPHA-T-BUTOXYCARBONYL-L-PHENYLALANINE
  • N-ALPHA-T-BOC-L-PHENYLALANINE
  • T-BUTYLOXYCARBONYL-L-PHENYLALANINE
  • TBOC-L-PHENYLALANINE
  • (S)-2-TERT-BUTOXYCARBONYLAMINO-3-PHENYL-PROPIONIC ACID
  • RARECHEM AL BE 0755
  • N-Boc-L-phenylalanine,99%e.e.
  • (Tert-Butoxy)Carbonyl Phe-OH
  • (2S-2-[(2-MethylpropaN-2-Yloxycarbonylamino]-3-Phenylpropanoic Acid
  • N-(tert-Butoxycarbonyl)-L-phenylalanine &gt
  • BOC-ph-OH