BOC-DL-PHE-OH
- Product Name
- BOC-DL-PHE-OH
- CAS No.
- 4530-18-1
- Chemical Name
- BOC-DL-PHE-OH
- Synonyms
- BOC-DL-PHE-OH;Boc-N-Me-D-Phe;Boc-N-Me-Phe-OH;BOC-DL-PHENYLALANINE;BOC-DL-PHE-OH USP/EP/BP;N-Boc-DL-phenylalanine,95%;N-Boc-DL-phenylalanine, 95%;N-Methyl-Boc-D-phenylalanine;(Tert-Butoxy)Carbonyl DL-Phe-OH;Boc-DL-phenylalanine≥ 99% (HPLC)
- CBNumber
- CB8676270
- Molecular Formula
- C14H19NO4
- Formula Weight
- 265.3
- MOL File
- 4530-18-1.mol
BOC-DL-PHE-OH Property
- Melting point:
- 106-108 °C
- Boiling point:
- 426.6±38.0 °C(Predicted)
- Density
- 1.160±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- pka
- 3.88±0.10(Predicted)
- form
- Solid
- color
- White to off-white
- CAS DataBase Reference
- 4530-18-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B6486
- Product name
- Boc-DL-Phe-OH
- Packaging
- 25G
- Price
- $72
- Updated
- 2025/07/31
- Product number
- B6486
- Product name
- Boc-DL-Phe-OH
- Packaging
- 100G
- Price
- $178
- Updated
- 2025/07/31
- Product number
- 111403
- Product name
- Boc-DL-Phe-OH
- Purity
- ≥98%
- Packaging
- 100g
- Price
- $255
- Updated
- 2021/12/16
- Product number
- AS91734
- Product name
- N-Boc-DL-Phenylalanine
- Purity
- 95+%
- Packaging
- 100g
- Price
- $266
- Updated
- 2021/12/16
- Product number
- FB47933
- Product name
- Boc-DL-phenylalanine
- Packaging
- 100g
- Price
- $220
- Updated
- 2021/12/16
BOC-DL-PHE-OH Chemical Properties,Usage,Production
Uses
2-(tert-butoxycarbonylamino)-3-phenylpropanoic acid is a phenylalanine derivative[1].
Synthesis
150-30-1
24424-99-5
4530-18-1
General procedure for the synthesis of 2-((tert-butoxycarbonyl)amino)-3-phenylpropionic acid from DL-phenylalanine and di-tert-butyl dicarbonate: DL-phenylalanine (1 g, 6.05 mmol) was suspended in a mixture of dioxane (15 mL) and NaOH (2M aqueous solution; 3.63 mL, 7.26 mmol) at 0 °C. Subsequently, di-tert-butyl dicarbonate (1.546 mL, 6.66 mmol) was added slowly and dropwise to this suspension. The reaction mixture was stirred continuously for 5 hours at room temperature. Upon completion of the reaction, the mixture was concentrated under vacuum to remove the solvent. Water (30 mL) was added to the concentrate and the pH of the mixture was adjusted to 3 by dropwise addition of cold 1.5 N HCl solution.The aqueous layer was extracted with ethyl acetate (3 x 50 mL) and the organic layers were combined and washed with brine solution (2 x 50 mL). The organic layer was dried over anhydrous sodium sulfate and concentrated to afford the target product 2-((tert-butoxycarbonyl)amino)-3-phenylpropanoic acid (1.3 g, 4.90 mmol, 81% yield) as a gelatinous liquid. The product was confirmed by 1H NMR (400 MHz, DMSO-d6) and mass spectrometry (ESI): 1H NMR δ 12.6 (br-s, 1H), 7.32-7.26 (m, 5H), 7.10-6.95 (br-s, 1H), 4.12-4.00 (m, 1H), 3.05-2.92 (m, 1H), 2.87- 2.75 (m, 1H), 1.31 (s, 9H); MS (ESI) m/z 266.2 [M+H]+.
References
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-882. DOI:10.1080/10408398.2012.708368
BOC-DL-PHE-OH Preparation Products And Raw materials
Raw materials
Preparation Products
BOC-DL-PHE-OH Suppliers
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View Lastest Price from BOC-DL-PHE-OH manufacturers
- Product
- BOC-DL-PHE-OH 4530-18-1
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2020-01-12