BOC-DL-PRO-OH

Product Name: BOC-DL-PRO-OH
CAS No.: 59433-50-0
Chemical Name: BOC-DL-PRO-OH
Synonyms: AKOS 91525;NSC 108689;BOC-DL-PRO-OH;BOC-DL-PROLINE;N-BOC-DL-PROLINE;N-Boc-DL-proline,98%;REF DUPL: Boc-DL-Pro-OH;BOC-DL-PRO-OH USP/EP/BP;Boc-DL-proline:Boc-DL-Pro-OH;(Tert-Butoxy)Carbonyl DL-Pro-OH
CBNumber: CB4224035
Molecular Formula: C10H17NO4
Formula Weight: 215.25
MOL File: 59433-50-0.mol

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BOC-DL-PRO-OH Property

Melting point:: 133-135°C
Boiling point:: 337.2±35.0 °C(Predicted)
Density: 1.201±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 4.01±0.20(Predicted)
Appearance: White to off-white Powder
optical activity: Consistent with structure
InChI: InChI=1S/C10H17NO4/c1-10(2,3)15-9(14)11-6-4-5-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)
InChIKey: ZQEBQGAAWMOMAI-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCCC1C(O)=O
CAS DataBase Reference: 59433-50-0(CAS DataBase Reference)

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Safety

HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B4285
Product name: Boc-DL-Pro-OH
Packaging: 5G
Price: $78
Updated: 2025/07/31

TCI Chemical

Product number: B4285
Product name: Boc-DL-Pro-OH
Packaging: 25G
Price: $234
Updated: 2025/07/31

TRC

Product number: B646218
Product name: (±)-N-(tert-Butoxycarbonyl)proline
Packaging: 2.5g
Price: $65
Updated: 2021/12/16

Oakwood

Product number: M03315
Product name: Boc-DL-Pro-OH
Purity: 98%
Packaging: 1g
Price: $10
Updated: 2021/12/16

AK Scientific

Product number: B032
Product name: Boc-DL-Proline
Packaging: 5g
Price: $14
Updated: 2021/12/16

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BOC-DL-PRO-OH Chemical Properties,Usage,Production

Uses

(±)-N-(tert-Butoxycarbonyl)proline is a useful reagent for the enantiospecific preparation of functionalized hindered triazolopyridinones.

Synthesis

To a 100 ml round bottom flask was added L-proline 1a (3.0 g, 26.06 mmol), sodium hydroxide (1.2 g, 28.66 mmol) and tert-butanol/water (20 ml/20 ml), respectively. Di-tert-butyl dicarbonate (6.3 g, 28.66 mmol) was slowly added to the reaction system under stirring at 0??C cooling and the temperature was then slowly raised to room temperature. After the end of the reaction was detected by TLC, the tert-butanol was removed by spinning under reduced pressure to obtain the crude product in the aqueous phase, which was washed three times with petroleum ether (3x 30 ml), after which it was adjusted to pH = 6 with 1N hydrochloric acid and extracted with ethyl acetate (3x 50 ml). The combined ethyl acetate extracts were dried over anhydrous sodium sulfate and the solvent was removed by spinning under reduced pressure to give a white solid pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester (5.49 g, 98% yield).

BOC-DL-PRO-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-DL-PRO-OH Suppliers

Canada 1 China 149 Europe 1 Germany 4 India 4 Japan 1 Ukraine 1 United Kingdom 5 United States 17 Global 183

Anhui Dexinjia Biopharm Co., Ltd

Tel: 82375893 15553111391
Email: 3276840968@qq.com
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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
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Email: market03@meryer.com
Country: China
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Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
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TAIYUAN RHF CO.,LTD.

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Shijiazhuang Sdyano Fine Chemical Co., Ltd.

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ProdList: 2850
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Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
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GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
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Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
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ProdList: 11777
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View Lastest Price from BOC-DL-PRO-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-DL-Pro-OH 59433-50-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T
Release date: 2023-11-16

Anhui Dexinjia Biopharm Co., Ltd

Product: BOC-DL-Proline 59433-50-0
Price: US $200.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 20TONS
Release date: 2024-06-04

Career Henan Chemical Co

Product: 6-FLUOROURACIL 59433-50-0
Price: US $3.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-08-07

59433-50-0, BOC-DL-PRO-OHRelated Search:

A-pyrrolidone BOC-SER(TOS)-OCH3 BOC-D-TYR(TBU)-OH Methyl N-(tert-butoxycarbonyl)-L-threoninate N-Boc-4-oxo-L-Proline methyl ester BOC-TRP(BOC)-OH Boc-Tyr-OtBu Boc-D-Ser(tBu)-OH BOC-DL-PHE-OH BOC-DL-LEU-OH H2O D-Alanine tert-butyl ester hydrochloride BOC-D-Alanine DL-Proline

PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER

BOC-DL-PROLINE

BOC-DL-PRO-OH

1-(TERT-BUTOXYCARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID

AKOS 91525

N-BOC-DL-PROLINE

REF DUPL: Boc-DL-Pro-OH

1-(tert-butoxycarbonyl)proline [Boc-DL-Pro-OH]

1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-diMethylethyl) ester

1-tert-Butyl 1,2-pyrrolidinedicarboxylate

N-(tert-Butoxycarbonyl)pyrrolidine-2-carboxylic acid

NSC 108689

N-tert-Butoxycarbonyl-DL-proline

(Tert-Butoxy)Carbonyl DL-Pro-OH

1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid

Boc-DL-proline:Boc-DL-Pro-OH

1-[(2-methylpropan-2-yl)oxy-oxomethyl]-2-pyrrolidinecarboxylic acid

1-tert-boc-pyrrolidine-2-carboxylic acid

N-Boc-DL-proline,98%

1-tert-Butoxycarbonyl-DL-proline

BOC-DL-PRO-OH USP/EP/BP

59433-50-0

Boc Amino Acids

Boc-Amino acid series

Boc-Amino Acids and Derivative