Boc-Tyr-OtBu
- Product Name
- Boc-Tyr-OtBu
- CAS No.
- 18938-60-8
- Chemical Name
- Boc-Tyr-OtBu
- Synonyms
- Boc-Tyr-OtBu;Boc-L-Tyr-OtBu;Boc-Tyr-Otbu-OH;(Tert-Butoxy)Carbonyl Tyr-OtBu;Boc-L-tyrosine tert-butyl ester;N-Boc-L-tyrosine tert-Butyl Ester;N-[ tert-butoxycarbonyl ]-L- tyrosine tert-butyl ester;N-[(1,1-Dimethylethoxy)carbonyl]-L-tyrosine 1,1-dimethylethyl ester;L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-, 1,1-dimethylethyl ester;tert-butyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoate
- CBNumber
- CB21456688
- Molecular Formula
- C18H27NO5
- Formula Weight
- 337.41
- MOL File
- 18938-60-8.mol
Boc-Tyr-OtBu Property
- Melting point:
- 111-112 °C(Solv: ligroine (8032-32-4); ethyl acetate (141-78-6))
- Boiling point:
- 476.0±40.0 °C(Predicted)
- Density
- 1.117±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- Solid
- pka
- 9.75±0.15(Predicted)
- color
- White to off-white
- optical activity
- Consistent with structure
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H350May cause cancer
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- AS112825
- Product name
- Boc-Tyr-OtBu
- Purity
- 98%
- Packaging
- 5G
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FB72164
- Product name
- Boc-Tyr-OtBu
- Packaging
- 10g
- Price
- $63
- Updated
- 2021/12/16
- Product number
- FB72164
- Product name
- Boc-Tyr-OtBu
- Packaging
- 25g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- AS112825
- Product name
- Boc-Tyr-OtBu
- Purity
- 98%
- Packaging
- 25g
- Price
- $176
- Updated
- 2021/12/16
- Product number
- 9445CV
- Product name
- Boc-Tyr-OtBu
- Packaging
- 25g
- Price
- $182
- Updated
- 2021/12/16
Boc-Tyr-OtBu Chemical Properties,Usage,Production
Uses
Boc-Tyr-OtBu is a tyrosine derivative[1].
Synthesis
24424-99-5
16874-12-7
18938-60-8
To a solution of 9.82 g (0.041 mol) tert-butyl L-tyrosinate in 150 mL of dichloromethane and 20 mL of DMF was added 5.2 g (0.04 mol) of triethylamine, followed by 9.03 g (0.04 mol) of di-tert-butyl dicarbonate. The reaction mixture was stirred at room temperature for 2 h. Upon completion of the reaction, it was washed sequentially with 1N HCl (3 × 50 mL), saturated NaHCO3 solution (1 × 50 mL), and brine (1 × 50 mL). The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated in vacuum to give 13.59 g (98% yield) of white solid product. The structure of the product was confirmed by 300 MHz 1H NMR (CDCl3): δ 1.42 (s, 18H), 2.95 (d, 2H), 4.39 (dd, 1H), 5.01 (d, 1H), 6.15 (s, 1H), 6.70 (d, 2H), 7.00 (d, 2H).
References
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368
Boc-Tyr-OtBu Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Boc-Tyr-OtBu manufacturers
- Product
- Boc-Tyr-Otbu 18938-60-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T
- Release date
- 2023-11-13
- Product
- Boc-Tyr-OtBu 18938-60-8
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-08