Methyl 3-isoquinolinecarboxylate
- Product Name
- Methyl 3-isoquinolinecarboxylate
- CAS No.
- 27104-73-0
- Chemical Name
- Methyl 3-isoquinolinecarboxylate
- Synonyms
- METHYL ISOQUINOLINE-3-CARBOXYLATE;3-(Methoxycarbonyl)isoquinoline;METHYL 3-ISOQUINOLINECARBOXYLATE;Methyl 3-isoquinolinecarboxylate,98%;Methylisoquinoline-3-carboxylate,98%;3-Isoquinolinecarboxylicacidmethylester;ISOQUINOLINE-3-CARBOXYLIC ACID METHYL ESTER;3-Isoquinolinecarboxylic acid, methyl ester ,98%;Methyl 3-isoquinolinecarboxylate ISO 9001：2015 REACH
- CBNumber
- CB9188097
- Molecular Formula
- C11H9NO2
- Formula Weight
- 187.19
- MOL File
- 27104-73-0.mol
Methyl 3-isoquinolinecarboxylate Property
- Melting point:
- 86-88 °C (lit.)
- Boiling point:
- 321.94°C (rough estimate)
- Density
- 1.1963 (rough estimate)
- refractive index
- 1.4900 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder
- pka
- 2.58±0.30(Predicted)
- Appearance
- Off-white to light yellow Solid
- BRN
- 473630
- InChI
- InChI=1S/C11H9NO2/c1-14-11(13)10-6-8-4-2-3-5-9(8)7-12-10/h2-7H,1H3
- InChIKey
- ZBCGBIZQNMVMPC-UHFFFAOYSA-N
- SMILES
- C1C2=C(C=CC=C2)C=C(C(OC)=O)N=1
- CAS DataBase Reference
- 27104-73-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 338559
- Product name
- Methyl 3-isoquinolinecarboxylate
- Purity
- 98%
- Packaging
- 1g
- Price
- $78.5
- Updated
- 2025/07/31
- Product number
- M321470
- Product name
- MethylIsoquinoline-3-carboxylate
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- JK149322
- Product name
- Methyl 3-isoquinolinecarboxylate
- Packaging
- 250mg
- Price
- $16
- Updated
- 2021/12/16
- Product number
- OR21830
- Product name
- Methylisoquinoline-3-carboxylate
- Packaging
- 1g
- Price
- $32
- Updated
- 2021/12/16
- Product number
- JK149322
- Product name
- Methyl 3-isoquinolinecarboxylate
- Packaging
- 1g
- Price
- $52
- Updated
- 2021/12/16
Methyl 3-isoquinolinecarboxylate Chemical Properties,Usage,Production
Chemical Properties
Cream powder
Uses
Methyl 3-isoquinolinecarboxylate was used in the preparation of 3-acetylisoquinoline.
Definition
ChEBI: Methyl isoquinoline-3-carboxylate is a member of isoquinolines.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 25, p. 1081, 1982 DOI: 10.1021/jm00351a015
Synthesis
79815-19-3
27104-73-0
General procedure for the synthesis of methyl isoquinoline-3-carboxylate from methyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate: In a 250 mL aubergine vial, (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate (2) (4.23 g, 22.15 mmol) and N,N-dimethylformamide (50 mL) were added. Subsequently, potassium permanganate (2.97 g, 18.79 mmol) was added to the solution. After the reaction was carried out for 6 hours, ethanol (50 mL) was added and stirred for 30 minutes. After that, the solvent was removed and the residue was dissolved with methanol (30 mL). Finally, the residue was purified by column chromatography to give a colorless solid product (858 mg, 24.56% yield).
References
[1] RSC Advances, 2017, vol. 7, # 77, p. 48848 - 48852
[2] Journal of Agricultural and Food Chemistry, 2018, vol. 66, # 34, p. 8957 - 8965
[3] Patent: CN106986825, 2017, A. Location in patent: Paragraph 0023; 0031; 0032
Methyl 3-isoquinolinecarboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 3-isoquinolinecarboxylate manufacturers
- Product
- Methyl 3-isoquinolinecarboxylate 27104-73-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Kg/T
- Release date
- 2019-12-19