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2-(4-Methylphenyl)propanoic acid

Product Name
2-(4-Methylphenyl)propanoic acid
CAS No.
938-94-3
Chemical Name
2-(4-Methylphenyl)propanoic acid
Synonyms
2-p-Tolylpropanoic acid;2-(P-TOLYL)PROPIONIC ACID;(2RS)-2-(4-METHYLPHENYL)PROPANOIC ACID;Ibuprofen-3;2-(4-MethyL;5932B+5242:5246;IBUPROFEN IMP D;2-(4-Methylphenyl)pr;IBUPROFEN IMPURITY D;Ibuprofen EP Impurity D
CBNumber
CB1333307
Molecular Formula
C10H12O2
Formula Weight
164.2
MOL File
938-94-3.mol
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2-(4-Methylphenyl)propanoic acid Property

Melting point:
37-42 °C(lit.)
Boiling point:
231.67°C (rough estimate)
Density 
1.0041 (rough estimate)
refractive index 
1.518-1.52
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
4.44±0.10(Predicted)
color 
White to Off-White
BRN 
2251315
CAS DataBase Reference
938-94-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR3321
Product name
(2RS)-2-(4-methylphenyl)propanoic acid
Purity
certified reference material, pharmaceutical secondary standard
Packaging
50MG
Price
$691
Updated
2024/03/01
Sigma-Aldrich
Product number
522449
Product name
α,4-Dimethylphenylacetic acid
Purity
97%
Packaging
5g
Price
$151
Updated
2023/06/20
TRC
Product number
T536780
Product name
2-(p-Tolyl)propionicAcid
Packaging
1g
Price
$70
Updated
2021/12/16
TRC
Product number
T536780
Product name
2-(p-Tolyl)propionicAcid
Packaging
25g
Price
$300
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK986257
Product name
2-(4-Methylphenyl)propanoicacid
Purity
97%
Packaging
25g
Price
$325
Updated
2021/12/16
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2-(4-Methylphenyl)propanoic acid Chemical Properties,Usage,Production

Chemical Properties

clear yellow liquid after melting

Uses

2-(p-Tolyl)propionic acid (Ibuprofen EP Impurity D) is an impurity of Ibuprofen (I140000). Ibuprofen impurity D.

Uses

2-(p-Tolyl)propionic acid is an impurity of Ibuprofen (I140000). Ibuprofen impurity D.

Synthesis Reference(s)

Synthesis, p. 231, 1984 DOI: 10.1055/s-1984-30784
Tetrahedron Letters, 36, p. 5641, 1995 DOI: 10.1016/0040-4039(95)01035-G

General Description

α,4-Dimethylphenylacetic acid is also referred to as 2-(4-methylphenyl)propanoic acid. It is an alkaline decomposition product of azalomycin-B, a macrolide antibiotic produced by Streptomyces hygroscopicus var. azalomyceticus. The reaction of pinonic acid with bromine in water affords 2-(4-methylphenyl)propanoic acid.

2-(4-Methylphenyl)propanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(4-Methylphenyl)propanoic acid Suppliers

Belgium 1 Canada 1 China 229 Europe 2 Germany 3 India 12 Japan 1 Norway 1 Slovakia 1 Switzerland 1 United Kingdom 6 United States 21 Global 279
Acros Organics
Tel
--
Fax
--
Email
info@acros.com
Country
Belgium
ProdList
6772
Advantage
81
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View Lastest Price from 2-(4-Methylphenyl)propanoic acid manufacturers

Henan Fengda Chemical Co., Ltd
Product
2-(4-Methylphenyl)propanoic acid 938-94-3
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-16
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-(4-Methylphenyl)propanoic acid 938-94-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
2-(4-Methylphenyl)propanoic acid 938-94-3
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KG
Release date
2018-08-21

938-94-3, 2-(4-Methylphenyl)propanoic acidRelated Search:

Propionic acid METHYLSTYRENE Silicone oil (high temperature) 2,3-Dibromopropionic acid Chlorodimethylphenylsilane Propionic anhydride 2-Chloropropionic acid DL-Phenylalanine (S)-(+)-2-Phenylpropionic acid 1-Methyl-4-(methylsulfonyl)-benzene 2,2-Bis(hydroxymethyl)propionic acid IBUPROFEN IMP. D (EP): 2-(4-METHYLPHENYL)PROPANOIC ACID MM(CRM STANDARD) (S)-(+)-Ibuprofen Z-AIB-OH (R)-(-)-IBUPROFEN 1-Hydroxyibuprofen 1-Oxo Ibuprofen Ibuprofen Ethyl Ester

  • 2-(p-Tolyl)propionic acidalpha,4-Dimethylphenylacetic acid
  • 2-(4-Methylphenyl)pr
  • 2-(p-Tolyl)propionic acid, 98% 5GR
  • α-(p-Tolyl)propionic Acid
  • α,4-DiMethylbenzeneacetic Acid
  • Ibuprofen IMpurity-D -(EP)
  • Ibuprofen EP Impurity D
  • 5932B+5242:5246
  • 2-(4-METHYLPHENYL)PROPA
  • Ibuprofen-3
  • 2-(p-Tolyl)proplonic acid
  • Ibuprofen EP Impurity D (2-(p-Tolyl)propionic Acid)
  • (2S)-2-(4-methylphenyl)propanoate
  • IBUPROFEN IMP D
  • IBUPROFEN IMPURITY D
  • 4-METHYL-2-PHENYLPROPIONIC ACID
  • alpha,4-Dimethylphenylacetic acid 97%
  • (2R)-2-(4-Methylphenyl)propanoic acid
  • ALPHA,4-DIMETHYLPHENYLACETIC ACID
  • 2-(4-METHYLPHENYL)PROPANOIC ACID
  • 2-(4-METHYLPHENYL)PROPIONIC ACID
  • 2-(P-TOLYL)PROPIONIC ACID
  • (2RS)-2-(4-METHYLPHENYL)PROPANOIC ACID
  • 2-(p-Methylphenyl)propionic acid
  • a,4-Dimethylbenzeneacetic acid
  • 2-(p-Tolyl)propionic acid,98%
  • 2-p-Tolylpropanoic acid
  • α,4-dimethylphenylacetic acid
  • p-Methylhydratropic acid.
  • 2-(4-tolyl)propanoic acid
  • 2-(4-Tolyl)propionic acid
  • Methylphenylpropinoic acid
  • 2-p-Tolylpropanoic acid / 2-(4-Tolyl)propionic acid
  • Ibuprofen EP Impurity D：Ibuprofen Impurity D
  • (2RS)-2-(4-Methylphenyl)propanoic A
  • 2-(4-MethyL
  • Benzeneacetic acid, α,4-dimethyl-
  • Ibuprofen Impurity 4（Ibuprofen EP Impurity D）
  • p-Methyl isopropionic acid　
  • Ibuprofen Impurity DQ: What is Ibuprofen Impurity D Q: What is the CAS Number of Ibuprofen Impurity D Q: What is the storage condition of Ibuprofen Impurity D Q: What are the applications of Ibuprofen Impurity D
  • α,4-Dimethylphenylacetic acid
  • 2-(4-Methylphenyl)propanoicaci
  • 938-94-3
  • CH3C6H4CHCH3CO2H
  • CARBOXYLIC ACID
  • Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acids
  • C10
  • Organic Building Blocks
  • Aromatic Propionic Acids
  • Carboxylic Acids
  • Phenyls & Phenyl-Het
  • Carboxylic Acids
  • Phenyls & Phenyl-Het
  • Intermediates