2',3'-DIDEOXY-3'-FLUOROURIDINE

Product Name: 2',3'-DIDEOXY-3'-FLUOROURIDINE
CAS No.: 41107-56-6
Chemical Name: 2',3'-DIDEOXY-3'-FLUOROURIDINE
Synonyms: Fddurd;2',3'-DIDEOXY-3'-FLUOROURIDINE;2',3'-DIDEOXY-3'-FLUOROURIDINE;3'-FLUORO-2',3'-DIDEOXYURIDINE;URIDINE, 2',3'-DIDEOXY-3'-FLUORO-;2’,3’-Dideoxy-3’-fluorouridine, FddU;2',3'-DIDEOXY-3'-FLUOROURIDINE USP/EP/BP;2’,3’-Dideoxy-3’-fluorouridine, FddU, anti-HIV;1-(2,3-DIDEOXY-3-FLUORO-BETA-D-RIBOFURANOSYL)URACIL;5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidine)-3-fluoro-2-hydroxymethyltetrahydrofuran
CBNumber: CB2779445
Molecular Formula: C9H11FN2O4
Formula Weight: 230.19
MOL File: 41107-56-6.mol

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2',3'-DIDEOXY-3'-FLUOROURIDINE Property

Melting point:: 184-188 °C(lit.)
Density: 1.50±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: Aqueous Base (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly), Water
form: Solid
pka: 9.39±0.10(Predicted)
color: White to Off-White
optical activity: [α]20/D +10.5°, c = 0.5 in 1 M NaOH
BRN: 6064366

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Safety

Hazard Codes: Xn
Risk Statements: 68
Safety Statements: 22-36/37
WGK Germany: 1
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H341Suspected of causing genetic defects
Precautionary statements: P281Use personal protective equipment as required.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 393711
Product name: 2′,3′-Dideoxy-3′-fluorouridine
Purity: 95%
Packaging: 25mg
Price: $223
Updated: 2022/05/15

Sigma-Aldrich

Product number: 393711
Product name: 2′,3′-Dideoxy-3′-fluorouridine
Purity: 95%
Packaging: 100mg
Price: $695
Updated: 2022/05/15

TRC

Product number: D439960
Product name: 2'',3''-Dideoxy-3''-fluorouridine
Packaging: 250mg
Price: $745
Updated: 2021/12/16

TRC

Product number: D439960
Product name: 2'',3''-Dideoxy-3''-fluorouridine
Packaging: 10mg
Price: $90
Updated: 2021/12/16

TRC

Product number: D439960
Product name: 2'',3''-Dideoxy-3''-fluorouridine
Packaging: 25mg
Price: $130
Updated: 2021/12/16

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2',3'-DIDEOXY-3'-FLUOROURIDINE Chemical Properties,Usage,Production

Chemical Properties

Off-white solid

Uses

2'',3''-Dideoxy-3''-fluorouridine is a reactant used in the synthesis of 5''-trityl nucleosides as inhibitors of Plasmodium falciparum dUTPase.

Uses

2′,3′-Dideoxy-3′-fluorouridine can be used as a starting material in the synthesis of:

3′-fluoro 2′,3′-dideoxynucleoside analogs for in vitro antiviral activity studies.
3′-fluoro deoxyuridine monophosphate analogs as potential anti parasites.

General Description

2′,3′-Dideoxy-3′-fluorouridine (3′-fluoro-2′,3′-dideoxyuridine, FddUrd) is a fluorinated pyrimidine nucleoside analog of uridine. It has been studied extensively for its potential use as an antiviral agent against HIV.

2',3'-DIDEOXY-3'-FLUOROURIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2',3'-DIDEOXY-3'-FLUOROURIDINE Suppliers

Austria 1 Canada 1 China 33 Germany 1 Switzerland 2 United Kingdom 3 United States 7 Global 48

Shanghai Hanhong Scientific Co.,Ltd.

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Sigma-Aldrich

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Fuyang Ziyi Biological Pharmaceutical Co., Ltd.

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Zhengzhou Granlen Sciences, ltd.

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41107-56-6, 2',3'-DIDEOXY-3'-FLUOROURIDINERelated Search:

3'-Deoxy-3'-fluorothymidine 2',3'-DIDEOXY-3'-FLUOROURIDINE 3'-Deoxy-3'-fluoro-5'-O-trityl-D-thymidine 5'-O-ACETYL-2'-3'-DIDEOXY-3'-FLUORO-URIDINE 5-CHLORO-2',3'-DIDEOXY-3'-FLUORO-URIDINE FOSALVUDINE TIDOXIL 2',3'-dideoxy-5-fluorouridine 3'-Azido-2',3'-dideoxy-5-fluorouridine 5-fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate 5'-O-Benzoyl-3'-fluoro-2',3'-dideoxyuridine AURORA KA-635 5'-O-Anisoyl-3'-fluoro-2',3'-dideoxyuridine 3'-Fluoro-5'-O-toluoyl-2',3'-dideoxyuridine 3'-FLUORO 3'-DEOXYTHYMIDINE, [METHYL-3H(N)]- AURORA KA-625 AURORA KA-603 5'-O-t-Butyldimethylsilyl-3'-fluoro-2',3'-dideoxyuridine AURORA KA-624

URIDINE, 2',3'-DIDEOXY-3'-FLUORO-

3'-FLUORO-2',3'-DIDEOXYURIDINE

2',3'-DIDEOXY-3'-FLUOROURIDINE

5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidine)-3-fluoro-2-hydroxymethyltetrahydrofuran

Fddurd

1-(2,3-DIDEOXY-3-FLUORO-BETA-D-RIBOFURANOSYL)URACIL

2’,3’-Dideoxy-3’-fluorouridine, FddU

2',3'-DIDEOXY-3'-FLUOROURIDINE USP/EP/BP

1-((2R,4S,5R)-4-Fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

2’,3’-Dideoxy-3’-fluorouridine, FddU, anti-HIV

2',3'-DIDEOXY-3'-FLUOROURIDINE

41107-56-6

C9H11FN2O4

Building Blocks

Heterocyclic Building Blocks

Pyrimidines

Nucleosides

Oligonucleotide Synthesis

Specialty Synthesis

Heterocyclic Compounds