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METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID

Product Name
METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID
CAS No.
167300-06-3
Chemical Name
METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID
Synonyms
3-(Methoxycarbonyl);METHY-2-METHYL-5-CARBOXYLICBENZOIC ACID;3-(Methoxycarbonyl)-4-Methylbenzoic acid;4-METHYL-3-(METHOXYCARBONYL)BENZOIC ACID;METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID;1,3-Benzenedicarboxylic acid, 4-methyl-, 3-methyl ester
CBNumber
CB2781790
Molecular Formula
C10H10O4
Formula Weight
194.18
MOL File
167300-06-3.mol
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METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID Property

Boiling point:
349.9±30.0 °C(Predicted)
Density 
1.243±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
4.00±0.10(Predicted)
Appearance
White to off-white Solid
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Safety

HS Code 
2917399590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M331698
Product name
3-(Methoxycarbonyl)-4-methylbenzoicAcid
Packaging
1g
Price
$310
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0299451
Product name
METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID
Purity
95.00%
Packaging
5MG
Price
$496.75
Updated
2021/12/16
AK Scientific
Product number
8530AA
Product name
3-(Methoxycarbonyl)-4-methylbenzoicacid
Packaging
250mg
Price
$139
Updated
2021/12/16
AK Scientific
Product number
8530AA
Product name
3-(Methoxycarbonyl)-4-methylbenzoicacid
Packaging
5g
Price
$784
Updated
2021/12/16
Chemenu
Product number
CM156464
Product name
3-(methoxycarbonyl)-4-methylbenzoicacid
Purity
95+%
Packaging
10g
Price
$785
Updated
2021/12/16
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METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID Chemical Properties,Usage,Production

Synthesis

675148-96-6

167300-06-3

Methyl 5-formyl-2-methylbenzoate (268 mg, 1.5 mmol) was used as starting material and dissolved in N,N-dimethylformamide (DMF, 5 mL). Subsequently, Oxone (1.110 g, 1.8 mmol) was added to the solution and the reaction mixture was stirred at room temperature for 18 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate (EtOAc, 10 mL) followed by 0.5 M aqueous hydrochloric acid (20 mL). The organic phase was separated, dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure to afford the target product 3-(methoxycarbonyl)-4-methylbenzoic acid as an off-white powder (247 mg, 1% yield). The structure of the product was confirmed by 1H NMR (500 MHz, DMSO-d6): δ 8.38 (d, J = 1.8 Hz, 1H), 8.01 (dd, J = 7.9, 1.9 Hz, 1H), 7.48 (d, J = 8.0 Hz, 1H), 3.86 (s, 3H), 2.59 (s, 3H).

References

[1] Patent: WO2018/89433, 2018, A1. Location in patent: Paragraph 00317

METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID Suppliers

Alchem Pharmtech,Inc.
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View Lastest Price from METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID manufacturers

Career Henan Chemical Co
Product
METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID 167300-06-3
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg
Release date
2020-01-13

167300-06-3, METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACIDRelated Search:


  • METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID
  • 4-METHYL-3-(METHOXYCARBONYL)BENZOIC ACID
  • METHY-2-METHYL-5-CARBOXYLICBENZOIC ACID
  • 3-(Methoxycarbonyl)-4-Methylbenzoic acid
  • 3-(Methoxycarbonyl)
  • 1,3-Benzenedicarboxylic acid, 4-methyl-, 3-methyl ester
  • 167300-06-3