ANTI-HUMAN PARATHYROID HORMONE RECEPTOR
- Product Name
- ANTI-HUMAN PARATHYROID HORMONE RECEPTOR
- Chemical Name
- ANTI-HUMAN PARATHYROID HORMONE RECEPTOR
- Synonyms
- CRLR;CGRPR;CALCRL;ANTI-PTHR1;CGRP type 1 receptor;ANTI-PTH/PTHRP RECEPTOR;ANTI-PTH/PTHP RECEPTOR MOUSE MAB;ANTI-PARATHYROID HORMONE RECEPTOR 1;Anti-PTHR1 antibody produced in rabbit;ANTI-HUMAN PARATHYROID HORMONE RECEPTOR
- CBNumber
- CB2784100
- Formula Weight
- 0
- MOL File
- Mol file
ANTI-HUMAN PARATHYROID HORMONE RECEPTOR Property
- storage temp.
- −20°C
- form
- buffered aqueous solution
- biological source
- rabbit
Safety
- WGK Germany
- 3
- Storage Class
- 10 - Combustible liquids
N-Bromosuccinimide Price
- Product number
- SAB4502493
- Product name
- Anti-PTHR1 antibody produced in rabbit
- Purity
- affinity isolated antibody
- Packaging
- 100 μg
- Price
- $522
- Updated
- 2025/07/31
ANTI-HUMAN PARATHYROID HORMONE RECEPTOR Chemical Properties,Usage,Production
Uses
Anti-PTHR1 antibody detects endogenous levels of total PTHR1 protein.
PTHR1 (parathyroid hormone 1 receptor) gene is mapped to human chromosome 3p21.31. The gene encodes for a precursor (secretin-like class II G protein-coupled receptor) that matures to a receptor containing 593 amino acids. This receptor contains an extracellular loop with a PTH binding site and an intracellular signaling domain. It also includes seven transmembrane and helical segments. The gene is predominantly expressed in osteoblasts and renal tubular cells.
Biological Activity
Heterozygous mutation of PTHR1 (parathyroid hormone 1 receptor) gene is known to cause primary failure of tooth eruption in human, with partial eruption of posterior teeth and reduced alveolar growth process. PTHR1 is associated with bone remodeling (bone formation and resorption, anabolic and catabolic responses respectively) and calcium homeostasis. Blomstrand chondrodysplasia results due to complete loss of PTHR1 function, and is considered lethal.
ANTI-HUMAN PARATHYROID HORMONE RECEPTOR Preparation Products And Raw materials
Raw materials
Preparation Products
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