E3 ligase Ligand 10

Product Name: E3 ligase Ligand 10
CAS No.: 1073560-68-5
Chemical Name: E3 ligase Ligand 10
Synonyms: E3 ligase Ligand 10;L-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-L-prolyl-β-phenyl-;(S)-2-((S)-1-((S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)propanamido)-2-cyclohexylacetyl)pyrrolidine-2-carboxamido)-3,3-diphenylpropanoic acid;(2S)-2-{[(2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)propanamido]acetyl]pyrrolidin-2-yl]formamido}-3,3-diphenylpropanoic acid
CBNumber: CB28054704
Molecular Formula: C47H52N4O7
Formula Weight: 784.94
MOL File: 1073560-68-5.mol

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E3 ligase Ligand 10 Property

Boiling point:: 995.9±65.0 °C(Predicted)
Density: 1.256±0.06 g/cm3(Predicted)
pka: 3.36±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Ambeed

Product number: A1220567
Product name: (S)-2-((S)-1-((S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)propanamido)-2-cyclohexylacetyl)pyrrolidine-2-carboxamido)-3,3-diphenylpropanoicacid
Purity: 97%
Packaging: 25mg
Price: $246
Updated: 2021/12/16

Ambeed

Product number: A1220567
Product name: (S)-2-((S)-1-((S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)propanamido)-2-cyclohexylacetyl)pyrrolidine-2-carboxamido)-3,3-diphenylpropanoicacid
Purity: 97%
Packaging: 50mg
Price: $333
Updated: 2021/12/16

Ambeed

Product number: A1220567
Product name: (S)-2-((S)-1-((S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)propanamido)-2-cyclohexylacetyl)pyrrolidine-2-carboxamido)-3,3-diphenylpropanoicacid
Purity: 97%
Packaging: 100mg
Price: $480
Updated: 2021/12/16

Ambeed

Product number: A1220567
Product name: (S)-2-((S)-1-((S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)propanamido)-2-cyclohexylacetyl)pyrrolidine-2-carboxamido)-3,3-diphenylpropanoicacid
Purity: 97%
Packaging: 250mg
Price: $719
Updated: 2021/12/16

Ambeed

Product number: A1220567
Product name: (S)-2-((S)-1-((S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)propanamido)-2-cyclohexylacetyl)pyrrolidine-2-carboxamido)-3,3-diphenylpropanoicacid
Purity: 97%
Packaging: 1g
Price: $1796
Updated: 2021/12/16

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E3 ligase Ligand 10 Chemical Properties,Usage,Production

Uses

E3 ligase Ligand 10 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 10 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

IC 50

IAP

References

[1] Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575. DOI:10.1021/acs.jmedchem.7b00168

E3 ligase Ligand 10 Preparation Products And Raw materials

Raw materials

Preparation Products

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E3 ligase Ligand 10 Suppliers

China 14 United States 2 Global 16

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
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Country: China
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Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
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Email: 3003855609@qq.com
Country: China
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Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1615
Advantage: 58

TargetMol Chemicals Inc.

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Email: marketing@targetmol.com
Country: United States
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Nextpeptide Inc

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Bide Pharmatech Ltd.

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Email: product02@bidepharm.com
Country: China
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TargetMol Chemicals Inc.

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Country: China
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ShenZhen Trendseen Biological Technology Co.,Ltd.

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Country: China
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Shanghai Easy CDMO Co.,Ltd

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shanghaiaoderuikanglimitedcompany

Tel: 18902198068 18912886236
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Country: China
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1073560-68-5, E3 ligase Ligand 10Related Search:

E3 ligase Ligand 18 L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)- E3 ligase Ligand 14 rac-((2R,3S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine

E3 ligase Ligand 10

(S)-2-((S)-1-((S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)propanamido)-2-cyclohexylacetyl)pyrrolidine-2-carboxamido)-3,3-diphenylpropanoic acid

L-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-L-prolyl-β-phenyl-

(2S)-2-{[(2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)propanamido]acetyl]pyrrolidin-2-yl]formamido}-3,3-diphenylpropanoic acid

1073560-68-5