4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-

Product Name: 4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-
CAS No.: 873080-25-2
Chemical Name: 4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-
Synonyms: ZAP 180013;ZAP-180013 ，E0437;ZAP-180013, 10 mM in DMSO;5-Chloro-N-(4-chlorobenzyl)-2-(ethylsulfonyl)-N-(furan-2-ylmethyl)pyrimidine-4-carboxamide;4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-;Inhibitor,autoimmune,ZAP-70,tyrosine,T-cell,ZAP 180013,ZAP180013,Tyrosinase,ZAP-180013,antigen,inhibit
CBNumber: CB28108342
Molecular Formula: C19H17Cl2N3O4S
Formula Weight: 454.33
MOL File: 873080-25-2.mol

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4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)- Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris

Product number: 6821
Product name: ZAP180013
Purity: ≥98%(HPLC)
Packaging: 10
Price: $105
Updated: 2021/12/16

Tocris

Product number: 6821
Product name: ZAP180013
Purity: ≥98%(HPLC)
Packaging: 50
Price: $445
Updated: 2021/12/16

ChemScene

Product number: CS-0120291
Product name: ZAP-180013
Purity: 98.56%
Packaging: 5mg
Price: $180
Updated: 2021/12/16

ChemScene

Product number: CS-0120291
Product name: ZAP-180013
Purity: 98.56%
Packaging: 10mg
Price: $300
Updated: 2021/12/16

Ambeed

Product number: A1359461
Product name: 5-Chloro-N-(4-chlorobenzyl)-2-(ethylsulfonyl)-N-(furan-2-ylmethyl)pyrimidine-4-carboxamide
Purity: 98%
Packaging: 1mg
Price: $102
Updated: 2021/12/16

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4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)- Chemical Properties,Usage,Production

Uses

ZAP-180013 is a zeta-chain-associated protein kinase 70 (ZAP-70) inhibitor with an IC50 of 1.8 μM. ZAP-180013 inhibits the interaction of ZAP-70 SH2 domain with immunoreceptor tyrosine-based activation motif (ITAMs)[1].

storage

Store at -20°C

References

[1] Patrick R Visperas, et al. Identification of Inhibitors of the Association of ZAP-70 With the T Cell Receptor by High-Throughput Screen. SLAS Discov. 2017 Mar;22(3):324-331. DOI:10.1177/1087057116681407

4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)- Suppliers

China 28 United States 4 Global 32

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873080-25-2, 4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-Related Search:

ZAP70-IN-10t Benzoic acid, 4-[[[8-(aminocarbonyl)-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-c]pyrimidin-5-yl]amino]methyl]-

4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-

ZAP 180013

Inhibitor,autoimmune,ZAP-70,tyrosine,T-cell,ZAP 180013,ZAP180013,Tyrosinase,ZAP-180013,antigen,inhibit

5-Chloro-N-(4-chlorobenzyl)-2-(ethylsulfonyl)-N-(furan-2-ylmethyl)pyrimidine-4-carboxamide

ZAP-180013, 10 mM in DMSO

ZAP-180013 ，E0437

873080-25-2