ChemicalBook > CAS DataBase List > 3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE

3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE

Product Name
3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE
CAS No.
329205-68-7
Chemical Name
3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE
Synonyms
MTEP;MTEP, mGluR5 antagonist;MTEP hydrochloride >=98% (HPLC);2-methyl-4-(pyridin-3-ylethynyl)thiazole;3-(2-Methyl-thiazol-4-ylethynyl)-pyridine;3-[2-(2-Methyl-4-thiazolyl)ethynyl]pyridine;Pyridine, 3-[(2-methyl-4-thiazolyl)ethynyl]-;Pyridine, 3-[2-(2-methyl-4-thiazolyl)ethynyl]-;3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE;2-methyl-4-(2-pyridin-3-ylethynyl)-1,3-thiazole
CBNumber
CB2842239
Molecular Formula
C11H8N2S
Formula Weight
200.26
MOL File
Mol file
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3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE Property

Boiling point:
360.7±17.0 °C(Predicted)
Density 
1.26±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
methanol: 1mg/mL
DMSO: 5mg/mL
pka
3.41±0.12(Predicted)
form 
White to yellow solid.
color 
white to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
445874
Product name
mGluR5 Antagonist, MTEP - CAS 329205-68-7 - Calbiochem
Packaging
5mg
Price
$166
Updated
2024/03/01
Usbiological
Product number
045049
Product name
MTEP
Packaging
5mg
Price
$307
Updated
2021/12/16
AK Scientific
Product number
3014CR
Product name
2-Methyl-4-(pyridin-3-ylethynyl)thiazole
Packaging
50mg
Price
$451
Updated
2021/12/16
Matrix Scientific
Product number
175653
Product name
3-[2-(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine
Packaging
1g
Price
$540
Updated
2021/12/16
Matrix Scientific
Product number
175653
Product name
3-[2-(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine
Packaging
5g
Price
$1260
Updated
2021/12/16
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3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE Chemical Properties,Usage,Production

Uses

MTEP Hydrochloride is a potent mGlu5 receptor antagonist, acting as a negative allosteric modulator.

Biological Activity

Cell permeable: yes', 'Primary Target
mGluR5', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 5 nM in Ca2+-flux assay', 'Target Ki: 16 nM for mGluR5 (metabotropic glutamate receptor subtype-5)

3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE Suppliers

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329205-68-7, 3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINERelated Search:

MPEP FENOBAM

  • 3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE
  • MTEP
  • 3-(2-Methyl-thiazol-4-ylethynyl)-pyridine
  • 2-methyl-4-(pyridin-3-ylethynyl)thiazole
  • 3-[2-(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine
  • 2-methyl-4-(2-pyridin-3-ylethynyl)-1,3-thiazole
  • Pyridine, 3-[(2-methyl-4-thiazolyl)ethynyl]-
  • MTEP hydrochloride >=98% (HPLC)
  • Pyridine, 3-[2-(2-methyl-4-thiazolyl)ethynyl]-
  • MTEP, mGluR5 antagonist
  • 3-[2-(2-Methyl-4-thiazolyl)ethynyl]pyridine
  • 329205-68-7