Methyl 7-aminoheptanoate hydrochloride

Product Name: Methyl 7-aminoheptanoate hydrochloride
CAS No.: 17994-94-4
Chemical Name: Methyl 7-aminoheptanoate hydrochloride
Synonyms: CHEMPACIFIC 38337;Methyl 7-aminoheptanoate;7-AMINOHEPTANOICMETHYLESTER;Methyl 7-aminoheptanoate HCl;(7-methoxy-7-oxoheptyl)azanium;7-Amino-heptanoic acid methyl ester;METHYL 7-AMINOHEPTANOATE HYDROCHLORIDE;Methyl 7-aminoheptanoate hydrochloride?New;methyl ester -7-amino- Heptanoic acid hydrochloride (1:1);Heptanoic acid,7-amino-, methyl ester, hydrochloride (1:1)
CBNumber: CB2855026
Molecular Formula: C8H17NO2
Formula Weight: 159.23
MOL File: 17994-94-4.mol

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Methyl 7-aminoheptanoate hydrochloride Property

Melting point:: 119-121℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
Appearance: White to off-white Solid

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Safety

HS Code: 2921199990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

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N-Bromosuccinimide Price

TRC

Product number: A609920
Product name: 7-AminoheptanoicAcidMethylEsterHydrochloride
Packaging: 1g
Price: $140
Updated: 2021/12/16

TRC

Product number: A609920
Product name: 7-AminoheptanoicAcidMethylEsterHydrochloride
Packaging: 10g
Price: $1100
Updated: 2021/12/16

AK Scientific

Product number: W3908
Product name: Methyl7-aminoheptanoatehydrochloride
Packaging: 1g
Price: $74
Updated: 2021/12/16

Matrix Scientific

Product number: 119480
Product name: Methyl 7-aminoheptanoate hydrochloride
Purity: 95+%
Packaging: 5g
Price: $88
Updated: 2021/12/16

AK Scientific

Product number: W3908
Product name: Methyl7-aminoheptanoatehydrochloride
Packaging: 5g
Price: $104
Updated: 2021/12/16

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Methyl 7-aminoheptanoate hydrochloride Chemical Properties,Usage,Production

Uses

Methyl 7-aminoheptanoate is used in the synthesis of the antidepressant drug Amineptine (A634280).

Synthesis

67-56-1

929-17-9

17994-94-4

Thionyl chloride (1.81 mL, 24.8 mmol) was slowly added dropwise to a cooled suspension of 7-aminoheptanoic acid (1.8 g, 12.4 mmol) in methanol (30 mL) under stirring conditions, and the reaction temperature was controlled to be maintained between -5°C and -10°C. The reaction was carried out by stirring. After the thionyl chloride drop was completed, the reaction mixture was gradually warmed up to room temperature with continuous stirring overnight. Upon completion of the reaction, the solvent was removed by vacuum concentration to give a white solid product. The solid was ground twice with ether to give a final 2.38 g of 7-aminoheptanoic acid methyl ester hydrochloride (1:1) (5) as a white solid (theoretical yield 4.8 g, 100% yield).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 9, p. 2809 - 2812
[2] Patent: WO2011/91213, 2011, A2. Location in patent: Page/Page column 76-78
[3] Patent: WO2013/13113, 2013, A2. Location in patent: Page/Page column 72-73
[4] Journal of Medicinal Chemistry, 2006, vol. 49, # 20, p. 6094 - 6103
[5] Journal of Medicinal Chemistry, 2018, vol. 61, # 6, p. 2589 - 2603

Methyl 7-aminoheptanoate hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 7-aminoheptanoate hydrochloride Suppliers

Canada 1 China 124 India 3 Ukraine 1 United Kingdom 1 United States 11 Global 141

Shanghai Boyle Chemical Co., Ltd.

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Energy Chemical

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SpringPharma Tech Co.,Ltd

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View Lastest Price from Methyl 7-aminoheptanoate hydrochloride manufacturers

Huida Pharmaceutical Technology (Shanghai) Co., Ltd.

Product: Methyl 7-aminoheptanoate 17994-94-4
Price: US $0.00-0.00/kg
Min. Order: 0.1kg
Purity: 98%
Supply Ability: 100kg
Release date: 2023-03-08

Zhuozhou Wenxi import and Export Co., Ltd

Product: Methyl 7-aminoheptanoate 17994-94-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Pharmahands (Taizhou) Co., Ltd.

Product: Methyl 7-aminoheptanoate hydrochloride 17994-94-4
Price: US $530.00/Kg/Bag
Min. Order: 1g
Purity: 99%
Supply Ability: 100kg/month
Release date: 2020-09-15

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Methyl 7-aminoheptanoate

7-AMINOHEPTANOICMETHYLESTER

Methyl 7-aminoheptanoate hydrochloride 7-Amino-heptanoic acid methyl ester hydrochloride

Methyl 7-aminoheptanoate HCl

7-Amino-heptanoic acid methyl ester

CHEMPACIFIC 38337

(7-methoxy-7-oxoheptyl)azanium

Heptanoic acid,7-amino-, methyl ester, hydrochloride (1:1)

methyl ester -7-amino- Heptanoic acid hydrochloride (1:1)

7-Amino-Heptanoic Acid Methyl Ester Hydrochloride(WX600067)

Methyl 7-aminoheptanoate hydrochloride?New

METHYL 7-AMINOHEPTANOATE HYDROCHLORIDE

17994-94-4