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ergotamine

Product Name
ergotamine
CAS No.
113-15-5
Chemical Name
ergotamine
Synonyms
NSC 95090;ergotamin;ergotamine;Ergotamine (8CI);ergotamine USP/EP/BP;XCGSFFUVFURLIX-VFGNJEKYSA-N;12'-Hydroxy-2'-methyl-5'α-benzylergotaman-3',6',18-trione;12’-hydroxy-2’-methyl-5’alpha-(phenylmethyl)ergotaman-3’,6’,18-trione;6’,18-trione,12’-hydroxy-2’-methyl-5’-(phenylmethyl)-ergotaman-3(5’-alph;18-trione,12’-hydroxy-2’-methyl-5’-(phenylmethyl)-6(5’alpha)-ergotaman-3
CBNumber
CB2865180
Molecular Formula
C33H35N5O5
Formula Weight
581.66
MOL File
113-15-5.mol
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ergotamine Property

Melting point:
241-249℃
alpha 
D20 -160° (chloroform)
Boiling point:
651.33°C (rough estimate)
Density 
1.0998 (rough estimate)
refractive index 
1.7500 (estimate)
pka
pKa 6.40±0.09(H2O t=24.0) (Uncertain)
CAS DataBase Reference
113-15-5
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Safety

RIDADR 
1544
HazardClass 
6.1(b)
PackingGroup 
III
Hazardous Substances Data
113-15-5(Hazardous Substances Data)
Toxicity
LD50 in mice, rats, rabbits (mg/kg): 62, 80, 3 i.v.; in cats: 11 s.c. (Rothlin)
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Hazard and Precautionary Statements (GHS)

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ergotamine Chemical Properties,Usage,Production

Uses

Analgesic (specific in migraine).

Definition

ChEBI: A peptide ergot alkaloid that is dihydroergotamine in which a double bond replaces the single bond between positions 9 and 10.

brand name

Ergomar (Harvest);Ergostat (Parke-Davis); Wigrettes (Organon).

Purification Methods

Crystallise it from *benzene, then dry it by prolonged heating in high vacuum. It is very hygroscopic. [Beilstein 25 III/IV 964.]

ergotamine Preparation Products And Raw materials

Raw materials

Preparation Products

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ergotamine Suppliers

113-15-5, ergotamine Related Search:


  • 12’-hydroxy-2’-methyl-5’alpha-(phenylmethyl)ergotaman-3’,6’,18-trione
  • 18-trione,12’-hydroxy-2’-methyl-5’-(phenylmethyl)-6(5’alpha)-ergotaman-3
  • 6’,18-trione,12’-hydroxy-2’-methyl-5’-(phenylmethyl)-ergotaman-3(5’-alph
  • ergotamin
  • ergotamine
  • Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'α)-
  • Ergotamine (8CI)
  • NSC 95090
  • 12'-Hydroxy-2'-methyl-5'α-benzylergotaman-3',6',18-trione
  • (5'alpha)-12'-Hydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione
  • XCGSFFUVFURLIX-VFGNJEKYSA-N
  • Ergotaman-3',6',18-trione,12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'a)-
  • ergotamine USP/EP/BP
  • 113-15-5
  • Organics