DIHYDROERGOTAMINE MESYLATE
- Product Name
- DIHYDROERGOTAMINE MESYLATE
- CAS No.
- 11032-41-0
- Chemical Name
- DIHYDROERGOTAMINE MESYLATE
- Synonyms
- DCCK;DHETX;dihydroergotoxin;dihydro-ergotoxin;Dihydroergotoxine;9,10-Dihydroergotoxine;DIHYDROERGOTAMINE MESYLATE;Ergotoxine, dihydro- (8CI, 9CI);DIHYDROERGOTAMINE METHANESULFONATE;DIHYDROERGOTAMINE METHANESULFONATE SALT
- CBNumber
- CB6221629
- Molecular Formula
- C34H41N5O8S
- Formula Weight
- 679.78
- MOL File
- 11032-41-0.mol
DIHYDROERGOTAMINE MESYLATE Property
- solubility
- methanol: 21 mg/mL
- form
- powder
- color
- white
DIHYDROERGOTAMINE MESYLATE Chemical Properties,Usage,Production
Originator
Redergin,Lek
Uses
Cognition adjuvant.
Manufacturing Process
Dihydrotoxine is a mixture of three hydrogenated alkaloides of ergot spur. (Claviceps purpurea). 10 g ergotoxine (the mixture of ergocornine, ergocristine, ergocryptine 1:1:1) in 200 ml dioxane and 20 g Pd/BaSO4 were stirred at a H2 pressure 10 atmospheres at 80°C for 5 hours. The catalyst was filtered off, a filtrate was distilled to dryness in vacuum. The residue was in chloroform dissolved and shook with aluminum oxide. The Al2O3 was filtered off, the filtrate was crystallized after adding of hot benzene and cooling. Yield 6-8 g dihydroergotoxine. It crystallized with 1 mol of benzene. MP: 185°C.
brand name
Alkergot (Sandoz); Circanol(3M Pharmaceuticals); Deapril (Bristol-Myers Squibb);Gerimal (Watson); Hydergine (Novartis).
Therapeutic Function
Vasodilator