Sultopride
- Product Name
- Sultopride
- CAS No.
- 53583-79-2
- Chemical Name
- Sultopride
- Synonyms
- LIN 1418;Barnetil;Sultopride;Sultopridum;N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide;Benzamide, N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxy-;N-[(1-Ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-(methyloxy)benzamide;4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamid;Benzamide, N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxy- (9CI)
- CBNumber
- CB2875390
- Molecular Formula
- C17H26N2O4S
- Formula Weight
- 354.468
- MOL File
- 53583-79-2.mol
Sultopride Property
- Melting point:
- 181-182 °C
- Boiling point:
- 530.0±50.0 °C(Predicted)
- Density
- 1.1814 (rough estimate)
- refractive index
- 1.6930 (estimate)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 13.99±0.46(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- API0001590
- Product name
- BARNETIL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.01
- Updated
- 2021/12/16
- Product number
- CSN21847
- Product name
- Sultopride
- Packaging
- 50mg
- Price
- $595
- Updated
- 2021/12/16
- Product number
- CSN21847
- Product name
- Sultopride
- Packaging
- 5mg
- Price
- $102
- Updated
- 2021/12/16
- Product number
- CSN21847
- Product name
- Sultopride
- Packaging
- 10mg
- Price
- $179
- Updated
- 2021/12/16
- Product number
- CSN21847
- Product name
- Sultopride
- Packaging
- 25mg
- Price
- $357
- Updated
- 2021/12/16
Sultopride Chemical Properties,Usage,Production
Originator
Barnetil,Delagrange,France,1976
Definition
ChEBI: Sultopride is a member of salicylamides.
Manufacturing Process
A solution of 17.22 g of N-ethyl-α-aminomethylpyrrolidine in 360 ml of
pyridine is placed in a 1 l balloon flask. A solution of 3.51 g of phosphorus
trichloride in 40 ml of pyridine is added at ambient temperature. After the
mixture has been stirred for 1 hour, 10 g of 2-methoxy-5-ethylsulfonylbenzoic
acid is introduced. The mixture is heated under reflux for 4 ? hours. After
cooling, the solvent is evaporated under vacuum and the residue is dissolved
in 200 ml of 20% sodium hydroxide. The solution is extracted with 200 ml of
chloroform.
The organic solution is dried and filtered and the solvent is evaporated under
vacuum; the residue is dissolved in 150 ml of ethanol and the solution is
acidified with hydrochloric acid. The hydrochloride is dried without heating and
recrystallized from 100 ml of absolute ethanol. 7.2 g of N-(1-ethyl-2-
pyrrolidyl-methyl-2-methoxy-5-ethylsulfonylbenzamide hydrochloride is
produced. Melting point: 190°C to 193°C.
brand name
Banotil;Barnotil;Topral.
Therapeutic Function
Neuroleptic
Sultopride Preparation Products And Raw materials
Raw materials
Preparation Products
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