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Fluphenazine decanoate

Product Name
Fluphenazine decanoate
CAS No.
5002-47-1
Chemical Name
Fluphenazine decanoate
Synonyms
lyogen;ecanoate;dapotumd;sq10,733;modecate;moditendepot;zinyl)ethylester;prolixindecanoate;fluphenazinedepot;flufenazinedecanoate
CBNumber
CB0260394
Molecular Formula
C32H44F3N3O2S
Formula Weight
591.77
MOL File
5002-47-1.mol
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Fluphenazine decanoate Property

Melting point:
30-32°
Boiling point:
658.1±55.0 °C(Predicted)
Density 
1.149±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Practically insoluble in water, very soluble in ethanol and in methylene chloride, freely soluble in methanol.
pka
7.32±0.10(Predicted)
CAS DataBase Reference
5002-47-1
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Safety

RIDADR 
3249
RTECS 
HE0525000
HazardClass 
6.1(a)
PackingGroup 
II
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F0260000
Product name
Fluphenazine decanoate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
f0260000
Price
$153
Updated
2024/03/01
TRC
Product number
F598300
Product name
FluphenazineDecanoate(~90%)
Packaging
500mg
Price
$965
Updated
2021/12/16
ChemScene
Product number
CS-0013962
Product name
Fluphenazine decanoate
Purity
99.48%
Packaging
100mg
Price
$220
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0009087
Product name
FLUPHENAZINE DECANOATE
Purity
95.00%
Packaging
25MG
Price
$225.75
Updated
2021/12/16
AK Scientific
Product number
J96004
Product name
Fluphenazine decanoate
Packaging
250mg
Price
$320
Updated
2021/12/16
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Fluphenazine decanoate Chemical Properties,Usage,Production

Chemical Properties

Yellow Oil

Uses

Fluphenazine Decanoate is used in psychotropic drug treatments like those relating to schizophrenia. Antipsychotic.

Definition

ChEBI: Fluphenazine decanoate is the prodrug of fluphenazine, an antipsychotic drug used for the symptomatic management of psychosis in patients with schizophrenia. It has a role as a phenothiazine antipsychotic drug, a prodrug and a dopaminergic antagonist. It is a member of phenothiazines, a decanoate ester, an organofluorine compound and a N-alkylpiperazine. It is functionally related to a fluphenazine.

Clinical Use

Antipsychotic
Schizophrenia and other psychoses

Drug interactions

Potentially hazardous interactions with other drugs
Anaesthetics: enhanced hypotensive effect.
Analgesics: increased risk of convulsions with tramadol; enhanced hypotensive and sedative effects with opioids.
Anti-arrhythmics: increased risk of ventricular arrhythmias with anti-arrhythmics that prolong the QT interval; increased risk of ventricular arrhythmias with amiodarone and dronedarone - avoid; increased risk of ventricular arrhythmias with disopyramide.
Antibacterials: increased risk of ventricular arrhythmias with delamanid and moxifloxacin - avoid
Antidepressants: increased risk of ventricular arrhythmias with tricyclics, citalopram, escitalopram; possible increased risk of convulsions with vortioxetine
Antiepileptics: antagonises anticonvulsant effect.
Antimalarials: increased risk of ventricular arrhythmias with artenimol with piperaquine and artemether/lumefantrine - avoid.
Antipsychotics: increased risk of ventricular arrhythmias with droperidol, pimozide and risperidone - avoid; avoid use of depot formulations with clozapine (cannot be withdrawn quickly if neutropenia occurs).
Antivirals: increased risk of ventricular arrhythmias with saquinavir - avoid; concentration possibly increased with ritonavir.
Anxiolytics and hypnotics: increased sedative effects
Atomoxetine: increased risk of ventricular arrhythmias.
Beta-blockers: enhanced hypotensive effect; increased risk of ventricular arrhythmias with sotalol
Cytotoxics: increased risk of ventricular arrhythmias with arsenic trioxide
Diuretics: enhanced hypotensive effect.
Lithium: increased risk of extrapyramidal side effects and possibly neurotoxicity.
Pentamidine: increased risk of ventricular arrhythmias - avoid.
Avoid with drugs that prolong the QT interval.

Metabolism

The cytochrome P450 isoenzyme CYP2D6 is involved in fluphenazine metabolism.

Fluphenazine decanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Fluphenazine decanoate Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
Advantage
58
TargetMol Chemicals Inc.
Tel
021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7934
Advantage
58
GIHI CHEMICALS CO.,LTD
Tel
0086-571-86217390
Fax
0086-571-86217391
Email
Sales@gihichem.com
Country
China
ProdList
861
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17982
Advantage
56
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16687
Advantage
50
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9503
Advantage
50
Watson Biotechnology Co.,Ltd
Tel
027-027-59207879 18140587686
Fax
QQ:1972026995
Email
kf@3600chem.com
Country
China
ProdList
4699
Advantage
55
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View Lastest Price from Fluphenazine decanoate manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
Fluphenazine decanoate 5002-47-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-29

5002-47-1, Fluphenazine decanoate Related Search:


  • FluphenazineCecanoate
  • FLUPHENAZINEDECANATE
  • Decanoic acid, 2-[4-[3-[2-(trifluoromethyl) -10H-phenothiazin-10-yl]propyl]-1-piperazinyl]ethyl ester
  • Decanoic acid 2-[4-[3-(2-trifluoromethyl-10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethyl ester
  • Decanoic acid fluphenazine
  • 2-(4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-1-piperazinyl)ethyld
  • dapotumd
  • decanoicacid,2-(4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-1-pipera
  • ecanoate
  • flufenazinedecanoate
  • prolixindecanoate
  • sq10,733
  • zinyl)ethylester
  • 2-(4-(3-(2-(trifluoroMethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethyl decanoate
  • modecate
  • moditendepot
  • fluorophenazinedecanoate
  • fluphenazinedepot
  • lyogen
  • FLUPHENAZINE DECANOATE
  • fluphenazine o-decanoate
  • 2-[4-[3-(2-(TRIFLUOROMETHYL)PHENOTHIAZIN-10-YL)PROPYL]PIPERAZIN-1-YL]ETHYL DECANOATE
  • butanoic acid 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethyl ester
  • Fluphenazine decanoate CRS
  • Fluphenazine octanoate CRS
  • Fluphenazine Decanoate (~90%)
  • 5002-47-1
  • C32H44F3N3O2S
  • 59177
  • Organics
  • API