(R)-2-(2-Chlorophenyl)pyrrolidine
- Product Name
- (R)-2-(2-Chlorophenyl)pyrrolidine
- CAS No.
- 823188-58-5
- Chemical Name
- (R)-2-(2-Chlorophenyl)pyrrolidine
- Synonyms
- (R)-2-(2-Chlorophenyl)pyrrolidine;(2R)-2-(2-chlorophenyl)pyrrolidine;Pyrrolidine,2-(2-chlorophenyl)-, (2R)-
- CBNumber
- CB2875729
- Molecular Formula
- C10H12ClN
- Formula Weight
- 181.66
- MOL File
- 823188-58-5.mol
(R)-2-(2-Chlorophenyl)pyrrolidine Property
- Boiling point:
- 254.1±33.0 °C(Predicted)
- Density
- 1.129±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 9.45±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FC151298
- Product name
- (R)-2-(2-Chlorophenyl)pyrrolidine
- Packaging
- 250mg
- Price
- $267.5
- Updated
- 2021/12/16
- Product number
- FC151298
- Product name
- (R)-2-(2-Chlorophenyl)pyrrolidine
- Packaging
- 500mg
- Price
- $465
- Updated
- 2021/12/16
- Product number
- CCH0038887
- Product name
- (R)-2-(2-CHLOROPHENYL)PYRROLIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.21
- Updated
- 2021/12/16
- Product number
- FC151298
- Product name
- (R)-2-(2-Chlorophenyl)pyrrolidine
- Packaging
- 50mg
- Price
- $77
- Updated
- 2021/12/16
- Product number
- AS8672
- Product name
- (R)-2-(2-Chlorophenyl)pyrrolidine
- Purity
- 95+% ee
- Packaging
- 1g
- Price
- $729
- Updated
- 2021/12/16
(R)-2-(2-Chlorophenyl)pyrrolidine Chemical Properties,Usage,Production
Chemical Properties
Flashing point: 107.5 °C . Vapour pressure: 0.0176mmHg at 25°C. (R)-2-(2-Chlorophenyl)pyrrolidine is a chiral molecule whose optical isomer is (S)-2-(2-Chlorophenyl)pyrrolidine.
Physical properties
A colorless crystal
Uses
(R)-2-(2-Chlorophenyl)pyrrolidine can be used as an intermediate for organic synthesis.
Synthesis
To a dry Schlenk flask under nitrogen is added 0.540 g of (R, R)- (+)-ETHYLENE-1, 2- bis (N5-4, 5,6, 7-TETRAHYDRO-L-INDENYL) titanium difluoride and 120 mL of dry THF. To this solution are added under nitrogen in the following order: 2- (2-chlorophenyl)-pyrroline (15 g), phenylsilane (15 g), pyrrolidine (0.48 mL), and MeOH (0.24 mL). The solution is stirred at RT for 48 h, then the mixture is diluted with 350 mL of diethylether and carefully added with vigorous stirring to 1200 mL of 1 M HCI. The aqueous layer is separated and extracted with three portions of diethyl ether (300 mL each). The aqueous layer is made basic with 3M NAOH and extracted with 5 portions of diethyl ether (200 mL each). The combined ether layers are dried over magnesium sulfate and concentrated in vacuo. The residue is purified by vacuum transfer to give (R)-2-(2-Chlorophenyl)pyrrolidine (15 g, 93%) as a colorless oil.
(R)-2-(2-Chlorophenyl)pyrrolidine Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-2-(2-Chlorophenyl)pyrrolidine Suppliers
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- sales@carbosynth.com
- Country
- United Kingdom
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